Your Depression Might Not Be What Your Doctor Thinks It Is. What If Your Antidepressants Aren't Working Because Nobody's Looking at the Real Problem? You've tried the medications, and you've done the talk therapy, but nothing seems to be working. Or perhaps—you're stuck on drugs with side effects you hate, wondering if you'll ever feel normal again. Most doctors follow a predictable script: you describe depression → they immediately get out the Rx pad and write for Prozac, or one of its many ...