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Two Onc Docs
Sam and Karine
171 episodes
6 days ago
This week’s episode will be focusing on Porphyrias…which is very timely since this week is HALLOWEEN and porphyrias are the diseases many people believe started the vampire legend!
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Medicine
Health & Fitness
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This week’s episode will be focusing on Porphyrias…which is very timely since this week is HALLOWEEN and porphyrias are the diseases many people believe started the vampire legend!
Show more...
Medicine
Health & Fitness
Episodes (20/171)
Two Onc Docs
Porphyria
This week’s episode will be focusing on Porphyrias…which is very timely since this week is HALLOWEEN and porphyrias are the diseases many people believe started the vampire legend!
Show more...
6 days ago
9 minutes

Two Onc Docs
Metastatic Breast Cancer 2025 UPDATE
This week’s episode is part 3 of our breast cancer series, with a 2025 update focusing on metastatic breast cancer systemic therapies, toxicities, and supportive care considerations.
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1 week ago
11 minutes

Two Onc Docs
Localized Breast Cancer 2025 UPDATE
This week’s episode will be focusing on treatment options for localized breast cancer with 2025 updates. We will go over important details on indications for adjuvant radiation, as well as therapies based on the ER/PR/HER-2 receptor status.
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2 weeks ago
17 minutes

Two Onc Docs
Breast Cancer Screening, Prevention & Intro 2025 UPDATE
October marks Breast Cancer Awareness Month. We are providing 2025 update for our 3 part breast cancer episodes, in part 1 today we cover an introduction on breast cancer screening, prevention.
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3 weeks ago
17 minutes

Two Onc Docs
Esophageal and Gastrosophageal Junction (GEJ) Cancer 2025 UPDATE
This week’s episode will be focusing on Esophageal and Gastrosophageal Junction (GEJ) Cancer. We will go over important details on the risk factors, diagnosis, and treatment for both localized and metastatic esophageal cancer.
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1 month ago
14 minutes

Two Onc Docs
Immune Thrombocytopenia Purpura ( ITP) 2025 UPDATE
This week’s episode will be focusing on Immune Thrombocytopenia Purpura ( ITP). We will go all the important details on causes, mechanism, diagnosis and treatment. The last time we covered this topic was in Sept 2022, and this comes up ALL the time in heme consults, and there will definitely be board review questions. It may also be tested on IM boards.
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1 month ago
9 minutes

Two Onc Docs
Bone Sarcomas 2025 UPDATE
This week’s episode will be an update on Bone Sarcomas. We will go over the important details on diagnosis, staging, subtypes and treatment of a few bone sarcomas. Just like Soft Tissue Sarcomas, these are RARE tumors encompassing 1% of all adult cancers and having multiple subtypes. They are more common in children, and most of our bone sarcoma recommendations that are testable are based on pediatric data.
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1 month ago
13 minutes

Two Onc Docs
Soft Tissue Sarcomas 2025 UPDATE
This week’s episode will be focusing on soft tissue sarcomas. We last recorded this topic in 2023, and well we have some new FDA approvals and updates since then. We will go over the important details on the diagnosis, subtypes and treatment of a few soft tissue sarcomas. These are RARE tumors encompassing 1% of all adult cancers and having multiple subtypes that range from noncancerous tumors such as desmoid tumors to aggressive cancers and everything in between.
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1 month ago
21 minutes

Two Onc Docs
Thrombotic Thrombocytopenic Purpura (TTP) and other TMAs 2025 UPDATE
Today’s episode will focus on an update for commonly tested Thrombotic microangiopathies (TMA) such as Thrombotic Thrombocytopenic Purpura (TTP). This will include the high yield facts on mechanism, presentation, diagnostic work-up, and treatment of TTP, and also discuss Hemolytic Uremic Syndrome (HUS), and atypical HUS.
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2 months ago
10 minutes

Two Onc Docs
Gastric Cancer 2025 UPDATE
This week’s episode will be focusing on Gastric Adenocarcinoma. We will go over all the important details on risk factors, diagnostic work-up, staging and treatment for both local regional disease and metastatic disease with updates in 2025 since we last covered this topic in 2023.
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2 months ago
18 minutes

Two Onc Docs
Endometrial (Uterine) Cancer 2025 UPDATE
We are updating another important GYN ONC topic: endometrial (uterine) cancer. We will go over all the important details on the risk factors, presentation, diagnosis, staging & treatment options. We will also cover rare uterine malignancies at the end of the episode.
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2 months ago
12 minutes

Two Onc Docs
Metastatic Kidney Cancer x Uromigos 2025 UPDATES (Part 2)
Today’s episode we will cover 2025 updates for metastatic renal cell carcinoma. We will discuss risk categories, treatment options, and variant histologies. We are so excited to have Dr. Tom Powles and Dr. Brian Rini from the urologic oncology podcast Uromigos sharing their expertise on today's episode as well!
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3 months ago
30 minutes

Two Onc Docs
Localized Kidney Cancer x Uromigos 2025 UPDATES (Part 1)
Today’s episode we will cover 2025 updates for localized renal cell carcinoma (RCC) with Dr. Tom Powles and Dr. Brian Rini from the urologic oncology podcast Uromigos! We will discuss risk factors, the presentation, staging, and treatment options.
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3 months ago
20 minutes

Two Onc Docs
Cervical Cancer 2025 UPDATE
This week’s episode will be focusing on Cervical Cancer with some updates since we last released this topic in 2022. We will go over important details on prevention, risk factors, diagnosis & treatment.
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3 months ago
11 minutes

Two Onc Docs
Oncologic Emergencies 2025 Update
This week’s episode is an update on a must-know topics both for new fellows & residents. We will go over clinically important oncologic emergencies including brain metastases, hypercalcemia of malignancy, cord compression and SVC syndrome.
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3 months ago
12 minutes

Two Onc Docs
ASCO 2025 Plenary - MATTERHORN
This week’s episode will be focusing on one of the GI plenary session abstracts presented at the ASCO Annual Meeting 2025, the MATTERHORN trial: phase 3 durvalumab + FLOT which is 5FU leucovorin, oxaliplatin and docetaxel in resectable gastric or GE junction CA.
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3 months ago
12 minutes

Two Onc Docs
Preparing for Fellowship 101
This week’s episode will be focusing on how to prepare for the start of heme/onc fellowship! We will go over some general advice on how to succeed, study tips and resources we used throughout fellowship as well as some tips on how to stay academically productive during training if you are planning for an academic career.
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4 months ago
15 minutes

Two Onc Docs
ASCO 2025 Plenary: SERENA-6
This week’s episode will be focusing on one of the 2025 plenary sessions: SERENA-6, Camizestrant, a novel selective estrogen receptor degrader (SERD) + CDK 4/6i for tx of emergent ESR1 during 1L endocrine-based therapy + ahead of progression in stage 4 HR+/Her-2 negative breast cancer. We discuss the trial design, endpoints, results, safety concerns, and how it fits into current practice.
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4 months ago
12 minutes

Two Onc Docs
Ovarian Cancer 2025 UPDATE
This week’s episode will be focusing on Ovarian Cancer with 2025 updates since we last covered this topic in 2022. We will go over all important details on the risk factors, presentation, diagnosis, staging & treatment options for both localized and metastatic disease.
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4 months ago
12 minutes

Two Onc Docs
ASCO Annual Meeting 2025 GU Updates
This week’s episode will be focusing on exciting data in GU presented at the 2025 ASCO Annual Meeting in prostate (including prognostication of PSA response in mCSPC, AMPLITUDE - PARPi in mCSPC), RCC (including updates in KN-564, CM-214 and PDIGREE), and finally bladder CA (with updates in NIAGARA and EV-302) among others.
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4 months ago
12 minutes

Two Onc Docs
This week’s episode will be focusing on Porphyrias…which is very timely since this week is HALLOWEEN and porphyrias are the diseases many people believe started the vampire legend!