This week's topics include AI and diabetes prevention, best exercise for knee OA, the Mediterranean diet and IBS, and stepping characteristics for CVD health.

This week's topics include benefits of nicotine reduction in cigarettes, new onset afib after heart surgery, brain structure in infants after maternal PFAS exposure, and food insecurity and blood pressure.

This week's topics include impact of social media on adolescent cognition, gene therapy for ADA deficiency, a new treatment for SLE, and AI in health care.  

This week's topics include a look at obesity medicines in adults, aldosterone and CVD risk, environmental impact of inhalers, and where U.S. antibiotics are originating.

This week's topics include an RSV antibody for healthy infants, cancer risk and CT in early life, treating pulmonary hypertension early, and medicines for bronchiectasis. 

This week's topics include alcohol and dementia, treating type 1 diabetes, outcomes when private equity takes over hospitals, and aspirin in CRC.

This week's topics include risk of second cancers after a first breast cancer, stalking and CVD, number of mental health disorders and dementia, and lipoprotein(a) and widespread vascular disease.

This week's topics include LSD and anxiety disorders, cardiac rehab in older people after MI, CT and pregnancy outcomes, and a new agent for treatment of resistant hypertension.

This week's topics include use of beta blockers after MI, revascularization in NSTEMI, discontinuation of blood thinners after ablation for afib, and use of RSV vaccination and hospitalization and other outcomes. Program notes: 0:53 Who needs a beta blocker after MI 1:53 Those with mild reduction of ejection fraction 2:53 Confined to those with 40-50% ejection fraction 3:15 Revascularization in NSTEMI 4:20 Composite outcome 5:20 Closes gap, do FFR 6:20 May not be physiologically significant 6:40 Is lifelong anticoagulation needed after ablation 7:41 Occurred less in those who stopped 8:30 RSV, cardiac events and hospitalizations 9:30 Lower hospitalization in those who got the vaccine 10:30 Acute respiratory illness hospitalization 11:30 Less benefit with existing CVD or immunocompromise 12:15 Several RSV vaccines 13:16 End

This week's topics include trauma predictive brain networks, AI and colonoscopy, ADHD treatment and behavior choices, and medication affordability around the world. Program notes: 0:44 Drug prices around the world 1:41 German prices as standard 2:40 Wide variation in price and affordability 3:40 Generic pricing 4:20 ADHD meds and behavior choices 5:20 Largely treated with methylphenidate 6:20 Significantly impacted suicidality and other behaviors 6:49 AI assistance and colonoscopy skills 7:49 When you stop AI assistance 8:50 Does this apply to other procedures that use AI 9:20 Trauma predictive brain networks 10:20 Use of hydrocortisone to damp down 11:20 Previous trauma impact 12:25 Developmental timing 13:30 End

This week's topics include who's delivering cancer care, new treatment for staph, diet and type 2 diabetes and potatoes and type 2 diabetes. Program notes: 0:44 Spuds are what we call potatoes 1:47 Followed for over 5million person years 2:45 No mechanism for why french fries are problematic 3:25 DASH4D diet for glycemic control 4:25 4 diets compared  5:25 Extends benefits outside hypertension 6:20 A new antibiotic for staph infections 7:20 IV therapy until cultures are negative 8:20 Cost of new therapy, cost effectiveness 8:40 Geographic variation in subspeciality cancer care 9:40 Highest income managed by specialists 10:40 Guidelines expanded 11:36 Telemedicine may help 12:10 End

This week's topics include men and women's use of health care and death after dementia dx, alteplase after stroke, obesity and IVF outcomes, and ultraprocessed foods, minimally processed foods, weight loss and cardiometabolic risk factors.

This week's topics include sex differences in response to antithrombotics, variants of Covid in people with persistent infection, making contraception free, and CRC screening in young adults.

This week's topics include severe flu complications for kids, a polygenic risk score for obesity, lifestyle intervention for cognition, and a case report on the intersection of HPV, immune dysfunction and squamous cell carcinoma.

This week's topics include the Human Phenotype project, CBT by telehealth and chronic pain, looking at RNA to characterize cancers, and air pollution and cognitive impairment with age. Program notes: 0:40 Human Phenotype project 1:43 Metabolomics 2:42 25 year follow up 3:43 Two control groups 4:00 CBT via telehealth or online 5:00 2000 people with chronic pain 6:00 Completion rate for videos lower 6:50 RNA analysis in cancer molecular diagnostics 7:50 4.8% failure rate 8:50 CNS or blood cancers primarily 9:25 Middle age exposure to air pollution and later cognition 10:25 Poorer processing speed earlier in life 11:58 End

This week's topics include reanimating hearts for transplant, suicidality among older adults, OUD treatment in primary care, and DCIS outcomes without surgery. Program notes: 0:44 Reanimating hearts for transplant 1:44 Allow heart to sit for two to four minutes 2:34 Outcomes in DCIS without surgery 3:34 Free of breast cancer six months after diagnosis 4:34 Numbers who went on to develop invasive disease low 5:34 May change how we approach DCIS 6:09 Suicidality around the world in older adults 7:09 Guns, pesticides, hanging 8:10 Increase primary care diagnosis of OUD 9:10 Three clinics in four U.S. states 10:10 Six million adults with OUD 11:10 Many physicians unaware of medicines 12:43 End

This week's topics include a comprehensive look at kid's health in the US, remaining life expectancy deficits after Covid, heart risk calculators in different ethnicities, and screening for hep C in the ED. Program notes: 0:40 AHA risk calculator in various ethnicities 1:40 Works well in all of them 2:40 Women and ethnicities 3:00 Hepatitis C screening in EDs 4:01 Many ethnicities represented 5:01 Identified as having the virus 6:01 Once they tested only 24% were referred 7:01 It was free testing 7:40 Failing US children 8:41 78% more likely to die in the US 9:41 Some of these are preventable 10:24 Life expectancy after the pandemic 11:24 Remains almost a year deficit 12:24 Deaths from overdose declining 13:17 End

This week's topics include a novel way to help aphasia post-stroke, a new type of hypertension medicine, ED boarding in older adults, and substandard chemotherapy drugs. Program notes: 0:40 A novel way to help aphasia after a stroke 1:40 C7 nerve ligation 2:42 Somatosensory function versus speech processing 3:36 Substandard anticancer medications 4:40 Tested many using HPLC 5:40 Alarming that one in six is impacted 6:40 Paying out of pocket 7:38 New type of medicine for treatment resistant hypertension 8:38 Need to follow electrolytes 9:00 ED boarding for elderly 10:00 Length of stay increased 11:00 Elderly more likely to suffer complications 12:00 CMS program for all inclusive care for elderly 12:49 End

This week's topics include an oral GLP-1 agonist, activating two satiety pathways, mental health in US adolescents, and stem cell tx for T1D Program notes: 0:40 Stem cells for type 1 diabetes 1:40 None had hypoglycemia afterwards 2:40 Autologous stem cells? 3:20 Oral GLP-1 agonist 4:20 Primary endpoint HbA1c reduction 5:20 Weight loss modest 6:20 Injectable GLP-1 plus an amylin analogue 7:20 Both those with diabetes and those without 8:20 No increased safety events 8:40 Mental health hospitalizations in adolescents 9:40 KID database 10:40 Females accounting for increase 11:40 67% of hospitalizations 12:57 End

This week's topics include using CT to help determine brain death, PET scanning for tau in Alzheimer's, screen time trajectories in US youth and mental health, and cannabis and your heart. Program notes: 0:35 Screen time trajectories in adolescents 1:33 31% had increasing addictive use trajectories 2:31 Females more involved in social media 3:06 Cannabis and CV risk 4:06 Smoking or using other products 5:06 Mechanisms include oxidative stress 6:06 Haven't regulated 6:28 Tau PET imaging in Alzheimer's 7:28 90% of tau positivity concurs with AB 8:30 Will blood test obviate? 9:30 Imaging to detect spread 9:43 CT perfusion for death by neurological criteria 10:43 Validation threshold 98% 11:43 Maybe adding another technique 12:43 End