Scientists at a bio-technology firm made headlines when they announced the “de-extinction” of the dire wolf, a species of wolf that went extinct on Earth over 10,000 years ago. Colossal Biosciences examined DNA from ancient dire wolf fossils and used it to create wolf puppies with traits of the extinct species. The gene editing technology sparked curiosity around the world, and although the new wolves were not exact replicas of the originals they had similar traits. The development raises serious questions about what de-extinction really means.

Mass extinctions have shaped the history of life on Earth, and nature has adapted across the millennia, but with almost half of all species already in decline, including some frogs, how seriously is de-extinction technology being taken?

Contributors: Dr. Beth Shapiro, Chief Science Officer, Colossal Biosciences, California, USA Dr. Daniel Pincheira-Donoso, Associate Professor of Evolutionary Biology and Global Change, Queen's University Belfast, UK Torill Kornfeldt, Science Journalist and author, Sweden Dr. Jay Odenbaugh, Professor of Philosophy, James F. Miller Professor of Humanities, Lewis and Clark College, Oregon, USA

Presenter: Charmaine Cozier Producer: Louise Clarke Researcher: Maeve Schaffer Editor: Tara McDermott Technical Producer: Craig Boardman Production Management Assistant: Liam Morrey