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The Drug Chat with Dr. Wambui
Dr. Wambui Wamburu
50 episodes
5 days ago
Dr. Wambui provides drug education using simple terms. Drugs will always be in our lives, let’s get empowered through knowledge to be better healthcare providers, caregivers, or patients.
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Medicine
Health & Fitness
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All content for The Drug Chat with Dr. Wambui is the property of Dr. Wambui Wamburu and is served directly from their servers with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.
Dr. Wambui provides drug education using simple terms. Drugs will always be in our lives, let’s get empowered through knowledge to be better healthcare providers, caregivers, or patients.
Show more...
Medicine
Health & Fitness
Episodes (20/50)
The Drug Chat with Dr. Wambui
Antiplatelets - Protease activated receptor 1 antagonists and a Miscellaneous class.

We are at the end of the road of our anti-platelet pathway exploration!!!! We look at 2 different ways of inhibiting the platelets from forming a clot and the different patient populations that these drugs are used. Hooray to the anti-platelets though I'm sure this isn't the end there must be another novel/cutting edge therapy just around the corner that a scientist/discoverer is just about to unveil......

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2 years ago
14 minutes 35 seconds

The Drug Chat with Dr. Wambui
Antiplatelets - Glycoprotein Platelet Inhibitors

In today's episode I give a gigantic high five to our scientists/discoveres! Figuring out yet another way to stop clot formation by working out the puzzle of how platelets work to form a clot. With that worked out they then make drugs that put a stop 🛑 to this and voila.... no clots are formed.

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2 years ago
15 minutes 15 seconds

The Drug Chat with Dr. Wambui
Antiplatelets - Thienopyridines

What a lovely name to pronounce Thienopyridines! Another nugget as to how platelets work to cause clots to form and how this class stops that from happening. Very Sci-Fi how these platelets work.

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2 years ago
16 minutes 21 seconds

The Drug Chat with Dr. Wambui
Antiplatelets - Platelet Aggregation Inhibitors.

In the year 1899 (others say 1897) Asprin was marketed by Bayer Pharmaceuticals. Yep and we still use it today talk of super drug. It's used and indicated in many areas but again tunnel vision in this episode where we are specifically interested in how are clots not formed when asprin is around.

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2 years ago
12 minutes 48 seconds

The Drug Chat with Dr. Wambui
Anticoagulants - Direct Thrombin Inhibitors (DTIs)
It's a wrap with the anticoagulants! The DTIs some interesting fun facts especially the one that has to do with Leeches 😊! They came into the market in the 2000s and have been very helpful on this anti-coagulation journey.
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2 years ago
12 minutes 15 seconds

The Drug Chat with Dr. Wambui
Anticoagulants - Factor 10a Inhibitors
Our amazing discoverers/scientists are always at work and in the years of 2000s they gave us this class. The other oral anticoagulants besides Warfarin. Factor 10a inhibitors part of the coagulation cascade a genius way to stop that clot.
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2 years ago
10 minutes 19 seconds

The Drug Chat with Dr. Wambui
Anticoagulants- Heparins.
We continue with our oldies but goodies. Heparin was first discovered in 1916!!! Ofcourse we have improved on it since then but they all basically work the same way. Still a huge part of our treatment protocols.
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2 years ago
13 minutes 19 seconds

The Drug Chat with Dr. Wambui
Anticoagulants - Warfarin

Warfarin is over 60 YEARS OLD yet it's the most prescribed oral anticoagulant. Listen up, refresh yourself on this oldie but really a good goodie.

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2 years ago
16 minutes 9 seconds

The Drug Chat with Dr. Wambui
Thrombolytics

A stroke is an emergency! We need to break down that clot, enter the thrombo(clot) lytics(disintegrate) class of drugs.

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2 years ago
16 minutes 19 seconds

The Drug Chat with Dr. Wambui
STROKES

In this episode we discuss strokes. The leading cause of disability, dementia and death globally. We answer questions like what causes a stroke and the types of strokes. This is an important conversation especially with the statistics that are out there. 

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2 years ago
14 minutes 2 seconds

The Drug Chat with Dr. Wambui
Alpha blockade, Alpha agonists, Vasodilators

It's the last few classes of the anti-hypertensive drugs. You may not use this routinely but...... they do lower blood pressure. Very interesting how these work. Or bodies are truly a work of art.

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2 years ago
17 minutes 57 seconds

The Drug Chat with Dr. Wambui
Diuretics

I am sure you have heard them called the "water pill" here is your opportunity to learn or remind thyself of exactly how does this reduce volume (make me pee more). Nope this is not a weight loss drug. 

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2 years ago
16 minutes 15 seconds

The Drug Chat with Dr. Wambui
Calcium Channel Blockers

Hey Podcasters! Calcium Channel Blockers (CCBs). Calcium is found in lots of places in your body but in this episode we stay in the heart and how calcium is used on a normal working day in your heart.. then we plug in the CCBs to treat hypertension. Listen up inquisitives.

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2 years ago
15 minutes 23 seconds

The Drug Chat with Dr. Wambui
Angiotensin 2 Receptor Blockers (ARBs)

The second of the RAAS system blockers! Very similar to the ACE Inhibitors with a little twist. "And all the Sartans assembled........."

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2 years ago
11 minutes 35 seconds

The Drug Chat with Dr. Wambui
Angiotensin Converting Enzyme Inhibitors.

Here we are with the ACE Inhibitors!! Yet another versatile class of drugs and oh how smart those scientists were to discover them. Listen up.

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2 years ago
14 minutes

The Drug Chat with Dr. Wambui
Beta Blockers

First of these drugs has been around since the 1960s!! We still use them. Some important info especially on the Side Effects.... Listen up!

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2 years ago
15 minutes 24 seconds

The Drug Chat with Dr. Wambui
Hypertension

Whichever set of data you look at globally or within your country cardiovascular diseases leads in the causes of death. Hypertension or High Blood Pressure is a risk factor for these diseases. In this session we will as usual check out how the body works on a normal day then apply the drugs that we use to treat. Stay tuned.......

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3 years ago
11 minutes 17 seconds

The Drug Chat with Dr. Wambui
Post-attachment Inhibitors

The description of how these drugs work is like a really good Sci-Fi movie! It's the last class of the antiretroviral drugs we look at. The first novel ARV drug in over a decade is in this class. Listen up!!

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3 years ago
14 minutes 29 seconds

The Drug Chat with Dr. Wambui
Integrase Strand Transfer Inhibitors

In this class, the virus is inside the cell however we stop its replication by inhibiting yet another enzyme.

Just this year this class got a new drug, how encouraging is that! We are still adding on to the ARVs who knows cure could be around the corner.

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3 years ago
12 minutes 5 seconds

The Drug Chat with Dr. Wambui
CCR5 Inhibitors

Amazing work figuring out how to stop the virus from getting into the host cells. Kudos to those drug discoverers. Today we look at a group of drugs that are entry inhibitors. Increase your knowledge on this.....

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3 years ago
12 minutes 56 seconds

The Drug Chat with Dr. Wambui
Dr. Wambui provides drug education using simple terms. Drugs will always be in our lives, let’s get empowered through knowledge to be better healthcare providers, caregivers, or patients.