Trade: Tegretol Class: Anticonvulsant MOA: Binds preferably to voltage gated Sodium channels in their inactive conformation, which prevents repetitive and sustained firing of an action potential.Indications: Partial and generalized tonic – clonic seizures Contraindications: AV Block, bundle branch block, agranulocytosis, bone marrow supression, monoamine oxidase inhibitor therapySide effects: Dizziness, drowsiness, ataxia, N/V, blurred vision, confusion, headache, transie...

Trade: SublimazeClass: Narcotic Analgesic MOA: Binds to opiate receptors producing analgesia and euphoriaIndication: PainContraindication: Use caution in traumatic brain injury, Respiratory depression Side effects: Respiratory depression, apnea, hypotension, N/V, dizziness, sedation euphoria, Sinus bradycardia, sinus tachycardia, palpitations, HTN, diaphoresis, syncopeDosingAdult 50-100mcg IM/IVPedi 1-2mcg/kg IM/IV

Trade: Valium Class: BenzodiazepineMOA: Binds to the benzodiazepine receptor and enhances the effects of GABAIndications: Anxiety, Skeletal muscle relaxation, anticonvulsant Contraindications: Children younger then 6 months, acute angle glaucoma, CNS depression, alcohol intoxication. Side effects: Respiratory depression, drowsiness, fatigue, headache, pain at the injection site, confusion, nausea, hypotension, cardiac arrest at high doses•Dosing:Adult: Anxiety: 2-10m...

Trade: MorphineClass: Opiate agonist/Narcotic Analgesic MOA: Binds to the opiate receptors. Reduces stimulation of the sympathetic nervous system caused by pain and anxiety. Reduction of sympathetic stimulation reduces heart rate, cardiac work, and myocardial O2 consumptionIndications: moderate to severe pain including chest pain associated with ACS, CHF, and pulmonary edema.Contraindications: Respiratory depression, shock.Side effects: Respiratory depression, hypotension, N/V, dizziness...

Trade: Toradol Class: NSAIDMOA: inhibits the production or prostaglandins in inflamed tissue, which decreases the responsiveness of pain receptors. Indications: Moderately severe acute painContraindications: Patients with a hx of peptic ulcer disease or GI bleed, patients with renal insufficiency, hypovolemic patients, 3rd trimester pregnancy, nursing mothers, allergy to other nsaids, stroke or head trauma, having surgery within the next 7 days. Side effects: headache, d...

First and foremost, THANK YOU to everyone who was listened to this Podcast over the past year. In just under 12 months we have risen to one of the top listened to and searched paramedic pod casts on spotify and apple podcasts. Again, thank you so much!If you love listening to my voice read these drugs, but want an extra visual aid to go along with it, my classmate is currently selling laminated, professionally printed copies of every drug we have covered. They are available one etsy RIG...

Trade – PhenerganClass – Antiemetic MOA - Decreases nausea and vomiting by antagonizing H1 receptors Indications – Nausea/Vomiting Contraindication – Altered level of consciousness, jaundice, bone marrow suppression, Use caution in seizure disorder.Side effects – Paradoxic excitation in children and older adults. Dosing:Adult - 12.5 - 25mg IV, IO, IMPedi - 2years and older 0.25 – 1 mg/kg IV, IO, IM

Trade – ApresolineClass – Vasodilator MOA – Directly dilates peripheral blood vesselsIndication – HTN associated with preeclampsia and eclampsia, HTN crisis Contraindication – Patients taking diazoxide or MAOI’s, coronary artery disease, stroke, angina, dissecting aortic aneurism, mitral valve and rheumatic heart disease. Side effects – Headache, angina, flushing, palpitations, reflex tachycardia, anorexia, N/V, diarrhea, hypotension, syncope, peripheral vasodilation, periphera...

Trade – CortefClass – Corticosteroid MOA – Reduces inflammation by multiple mechanisms. As a steroid it replaces the steroids that are lacking in adrenal insufficiency.Indications – Adrenal insufficiency, allergic reactions, anaphylaxis, asthma, COPDContraindications – Cushing Syndrome, known sensitivity to benzyl alcohol, Use with caution in diabetes, HTN, CHF, known systemic fungal infection, renal disease, idiopathic thrombocytopenia, psychosis, seizure disorder, GI disease, glaucoma....

Trade – PlavixClass – Antiplatelet MOA – Blocks platelet aggregation by antagonizing the IIb/IIIa receptors Indications – ACS, chronic coronary and vascular disease, ischemic stroke.Contraindications – Hx of intracranial hemorrhage, GI bleed or trauma.Side effects – Nausea, Abdominal pain, hemorrhage. Dosing : Unstable angina pectoris or non Q wave AMI.Adult – Loading dose 300-600mg POPedi – Not recommended for pedi patients

Trade – Nipride Class – Antihypertensive agentMOA – Causes direct relaxation of both arteries and veins Indication – HTN emergencies Contraindications – Hypotension, increased ICP, cerebrovascular disease, coronary artery disease, hepatic disease, renal disease, pulmonary disease.Side effects – Cyanide or thiocyanate toxicity, N/V, dizziness, headache, restlessness, abdominal pain, methemoglobinemia.Dosing Adult 0.3-10mcg/kg/minPedi 0.5 – 10mcg/kg/min

Trade – CyanokitMOA: Antidote, cyanide poisoning adjunct Binds with cyanide to form nontoxic cyanocobalamin, preventing its toxic effects; excreted renallyIndications: Treatment of known or suspected cyanide poisioning.Contraindications: None is the emergency settingSide Effects: Hypertension, allergic reactions, GI bleeding, nausea, vomiting, dyspepsia, dyspnea, dizziness, headache, injection site reactions.Dosage: Adult: 5 g IV infusion over 15 minutes at a rate of 1...

Trade – IsoptinClass – Calcium Channel blockerMOA – Blocks calcium from moving into the heart muscle cell, which prolongs conduction of the electrical impulses through the AV node.Indications – AF, HTN, paroxysmal SVT, Paroxysmal SVT prohylaxisContraindications – 2nd or 3rd degree AV block, Hypotension, cardiogenic shock, Sick sinus syndrome, WPW.Side effects – Sinus bradycardia, 1st, 2nd, or 3rd degree AV blocks, CHF, reflex tachycardia, transient asystole, hypotension.Dosing Adult ...

Trade – HaldolClass – Antipsychotic agent MOA – Selectively blocks postsynaptic dopamine receptorsIndications – Psychotic disorders, agitation Contraindications – Depressed mental status, Parkinson diseaseSide effects – extrapyramidal symptoms, drowsiness, tardive dyskinesia, hypotension, hypertension, VT, sinus tachycardia, QT prolongation, torsades de pointes. Dosing Adult: Mild agitation : 0.5-2mg PO/IMModerate agitation : 5-10mg PO/IM Severe agitation ...

Trade – CardeneClass – Calcium Channel blocker MOA – Blocks calcium movement into the smooth muscle of the blood vessel walls, causing vasodilation.Indication – Angina, HTNContraindication – Aortic stenosis, hypotension, use caution in heart failure, cardiac conduction abnormalities, Cerebrovascular disease, depressed AV node conduction. Side effects – Edema, headaches, flushing, sinus tachycardia, hypotension Dosages :Adult: 5mg/hr IV/IO Pedi: 0.5 – 5 mcg/kg/min

Trade: TetraViscClass: Anesthetic MOA: Short acting pain suppressantIndication: Topical anesthetic for eye injuriesContraindication: allergySide Effects: numbness, blurred vision in treated eye, mild short burning sensationDose: Adult: 1-2 drops every 5 minutes, repeat as needed Pediatric1-2 drops every 5 minutes, repeat as needed

Trade – Diprivan Class – Anesthetic MOA – Produces rapid and brief state of general anesthesia. Indication – Anesthesia inductionContraindication – HypovolemiaSide effects – Apnea, Cardiac arrhythmias, asystole, hypotension, hypertension.Dosing Initial induction: 1.5-3mg/kg IV/IO followed by a maintenance infusion.Adult maintenance infusion 25-75 mcg/kg/min IV/IO Pedi maintenance infusion 30-300 mcg/kg/min IV/IO

Trade – Dilantin Class – AnticonvulsantMOA – Depresses seizures by affecting the movement of sodium and calcium into neural tissue. Indication – Generalized tonic – clonic seizures.Contraindication – sinus bradycardia, sinoatrial block, second and third degree heart block, adam stokes syndrome, known sensitivity to hydantoins. Side effects – N/V, depression of cardiac conduction, sedation, nystagmus, tremors, ataxia, dysarthria, gingival hypertrophy, hirsutism, facial coarsenin...

Trade – Unfractionated Heparin Class – Anticoagulant MOA – Acts on antithrombin III to reduce the ability of the blood to form clots, thus preventing clot deposition in the coronary arteries. Indication – ACS, acute pulmonary embolism, DVTContraindication – Predisposed to bleeding, aortic aneurism, peptic ulcer. Dosing:AdultCardiac indications – 60 units/kgPulmonary embolism/ DVT – 80 units/kgPediCardiac indications – 75 units/kgPulmonary embolism/DVT 75 units/kg

Trade – ALTEPLASE RECOMBINANT-TPAClass– Thrombolytic Agent MOA – Dissolves thrombi plugs in the coronary arteries and reestablishes blood flow.Indication – ST segment elevation greater then 1mm in 2 or more contiguous leads, New or presumed new left bundle branch block. Contraindications – ST segment depression, Cardiogenic shock, Recent major surgery, cerebrovascular disease, recent (within 10 days) GI bleeding, recent trauma, severe HTN Systolic greater then 180 diastolic greater ...