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Optimization Academy with Dr. Greg Jones
Dr. Greg Jones
75 episodes
5 days ago
Welcome to the Optimization Academy Podcast! Here I will be interviewing some of my favorite innovators in the health care industry and beyond. We will be sharing tips and information on how to become the most powerful version of yourself using naturopathic and integrative medicine, fitness, nutrition, and more. Together we will give you the tools to be informed and empowered! Dr. Greg Jones is Naturopathic Physician, Navy Vet, Reformed Engineer, and Grumpy Dog Dad. His mission in medicine is to shift the conversation away from "sick" care to true healthiness and wellness.
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Health & Fitness
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All content for Optimization Academy with Dr. Greg Jones is the property of Dr. Greg Jones and is served directly from their servers with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.
Welcome to the Optimization Academy Podcast! Here I will be interviewing some of my favorite innovators in the health care industry and beyond. We will be sharing tips and information on how to become the most powerful version of yourself using naturopathic and integrative medicine, fitness, nutrition, and more. Together we will give you the tools to be informed and empowered! Dr. Greg Jones is Naturopathic Physician, Navy Vet, Reformed Engineer, and Grumpy Dog Dad. His mission in medicine is to shift the conversation away from "sick" care to true healthiness and wellness.
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Health & Fitness
Episodes (20/75)
Optimization Academy with Dr. Greg Jones
74. Stem Cells for Longevity, Healing, Treating Chronic Disease, Current and Future

In this episode, Dr. Jones sits down with Eric Stoffers, CEO and founder of BioXcellerator, a global leader in stem cell therapy and regenerative medicine. Stoffers is an international pioneer in health, immunity, and longevity, with a vision to make advanced therapies more accessible for patients with autoimmune, orthopedic, neurological, and degenerative conditions.

From his work at BioXcellerator to his leadership as Chairman of Solutions for a Healthier World, a nonprofit focused on improving lives through medicine, science, and education, Stoffers brings innovation and compassion to the future of healthcare.

Listeners will hear insights on the science behind stem cells, detailing the differences between various sources like adipose tissue, bone marrow, and umbilical cords. They explore the unique properties of mesenchymal stem cells (MSCs), contrasting them with exosomes and addressing common industry myths, including the use of embryonic cells.

You'll hear about the conditions showing the most promising results, from orthopedic and autoimmune issues to neurological injuries like TBIs and spinal cord damage. Eric also discusses the regulatory landscape that differentiates treatment in the U.S. from options abroad, the patient experience at his clinic in Medellin, Colombia, and why he believes regenerative medicine is the present, not the future.

📌 Eric Stoffers

Eric Stoffers is an international pioneer and innovator in stem cell therapy and research. As CEO and founder of BioXcellerator, he has advanced protocols to treat autoimmune and degenerative diseases, orthopedic injuries, spinal and neurological conditions, and more. He also serves as Chairman of Solutions for a Healthier World, a nonprofit dedicated to alleviating suffering and improving quality of life through medicine, education, and support for victims of tragic events.

🔗 Learn more about Eric Stoffers

Website: bioxcellerator.com

LinkedIn: www.linkedin.com/in/eric-stoffers-1853b885/


Connect with Dr. Greg Jones

Instagram: @doctorjones_doctorjones 

Enovative Wellness Center: https://enovativewellness.com/ 

🔬 Timestamps

  • Introduction to Stem Cell Therapy (00:00 - 01:09)

  • Dr. Jones's Skepticism and First Impressions of BioXcellerator (01:09 - 02:27)

  • Eric Stouffer's Journey from Restaurants to Regenerative Medicine (02:27 - 05:13)

  • How a Real Estate Deal Led to the Founding of BioXcellerator (05:13 - 07:04)

  • Why Colombia and Medellin Were Chosen for BioXcellerator (07:04 - 09:27)

  • Foundational Question: What Is a Stem Cell? (09:27 - 11:42)

  • What Is a Mesenchymal Stem Cell (MSC)? (11:42 - 13:02)

  • Autologous vs. Allogeneic Cells: Addressing Donor Rejection Concerns (13:02 - 14:46)

  • MSCs vs. Embryonic and Pluripotent Stem Cells (14:46 - 17:17)

  • The Difference Between Stem Cell Products in the U.S. vs. BioXcellerator (17:17 - 22:08)

  • Explaining the Difference Between Stem Cells and Exosomes (22:08 - 27:32)

  • Conditions with the Best Outcomes: Orthopedic, Autoimmune, and Neurological (27:32 - 31:36)

  • Treating Veterans for TBIs and Concussions (31:36 - 33:23)

  • Misunderstood and Overstated Claims in the Stem Cell Industry (33:23 - 35:49)

  • FDA Regulations: Why Can't We Do This in the States? (35:49 - 38:09)

  • The Myth That Stem Cell Therapy Is Unproven (38:09 - 39:15)

  • Pros and Cons of Different Stem Cell Sources (Autologous vs. Allogeneic) (39:15 - 42:44)

  • How BioXcellerator Measures and Tracks Patient Success Remotely (42:44 - 46:18)

  • The Patient Process: From Initial Consultation to Treatment in Medellin (46:18 - 50:35)

  • Why Are Large Stem Cell Doses Administered Over Multiple Days? (50:35 - 52:56)

  • The Pros and Cons of Medellin (and the Traffic!) (52:56 - 54:25)

  • The Future Role of Stem Cells in Regenerative and Longevity Medicine (54:25 - 57:50)

  • Advice for Listeners Hesitant About Stem Cell Therapy (57:50 - 01:00:30)

  • Advice Eric Would Give Himself 10 Years Ago (01:00:30 - 01:02:43)

  • Where to Learn More About BioXcellerator and Closing Remarks (01:02:43 - 01:05:21)

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5 days ago
1 hour 5 minutes 20 seconds

Optimization Academy with Dr. Greg Jones
73. VO₂ Max: Redefining Fitness and Longevity

In this episode, Dr. Greg Jones reconnects with Dr. Leonard Pastrana, pharmacist, educator, and co-founder of New Bio Age. Their conversation centers on VO₂ max, what it is, why it matters for healthspan, and how it’s becoming one of the most critical markers in longevity medicine.

They explain what VO₂ max measures, why traditional wearables often fall short, and how metabolic breath analysis provides real clinical data. You’ll hear about the impact of COVID-19 on cardiorespiratory fitness, why training zones (like zone 2 and interval training) matter, and how resistance training also supports VO₂ max.

Dr. Pastrana also talks about the role of peptides, recovery strategies, and supplements such as alpha-ketoglutarate and Leucinergy in supporting mitochondrial function and exercise performance. The episode concludes with a look at the future of metabolic testing, New Bio Age’s Clinical Longevity Certification, and the upcoming CALM 2026 event.


📌 Dr. Leonard Pastrana

Dr. Leonard Pastrana is a pharmacist, co-founder of nuBioAge, and a leader in cellular optimization and longevity medicine. As a Doctor of Pharmacy and faculty member at the American Academy of Anti-Aging Medicine (A4M), he is one of six certified clinical peptide therapy instructors worldwide and the only pharmacist in this role. Leonard empowers medical providers with cutting-edge tools and knowledge through initiatives like Nucleus, consults for pharmacies and supplement companies, and pioneers precision diagnostics, peptide therapies, and integrative health solutions. A sought-after speaker, his work focuses on mentorship, collaboration, and advancing standards in longevity medicine.


🔗 Learn more about Dr. Leonard Pastrana

Website: https://nubioage.com/about/
Instagram: www.instagram.com/leonardpastrana/


🔬 Timestamps

  • Introduction and Background (00:00 - 02:12)
  • Transition to Longevity and Functional Medicine (02:12 - 05:03)
  • The Longevity Summit and Long COVID (05:03 - 08:39)
  • Understanding VO₂ Max (08:39 - 12:40)
  • Testing Methods for VO₂ Max (12:40 - 19:59)
  • VO₂ Max as a Standard for Longevity (19:59 - 26:19)
  • Addressing Myths About VO₂ Max Decline (26:19 - 29:04)
  • Improving VO₂ Max Through Personalized Exercise (29:04 - 32:00)
  • The Role of Resistance Training in VO₂ Max (32:00 - 34:39)
  • Peptides and Their Impact on VO₂ Max (34:39 - 42:46)
  • The Future of VO₂ Max in Longevity Medicine (42:46 - 44:52)
  • Upcoming Events and Educational Opportunities (44:52 - 55:23)

As always, thanks for watching!

Don’t miss an episode! Subscribe and leave a review.

*****Click here to subscribe to our YouTube channel: / @drjonesnmdtv  

*****Follow us on Spotify: Optimization Academy with Dr. Greg Jones | Podcast on Spotify

Connect with Dr. Jones on Instagram:  / doctorjones_doctorjones  

*****Connect with Enovative Wellness Center on Facebook:/ gregjonesnmd  

*****Enovative Wellness Center: https://enovativewellness.com/

Disclaimer: The information shared on The Dr. Jones Optimization Podcast and its associated YouTube channel is intended for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Listening to this podcast or viewing its content does not create a doctor–patient relationship, and nothing shared should be interpreted as individualized medical guidance. Always consult with a qualified healthcare provider before making changes to your health regimen or managing a medical condition. The opinions expressed by Dr. Jones and his guests are their own and do not reflect official medical advice or recommendations

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2 weeks ago
55 minutes 24 seconds

Optimization Academy with Dr. Greg Jones
72. A New NAD+ Deep Dive: Energy, Aging, Supplements, and NAD IVs

In this episode, Dr. Jones talks again with Dr. Paul Anderson, naturopathic doctor, researcher, and teacher. He joined the podcast last year to talk about cholesterol and lipid labs. This time the focus is on NAD (Nicotinamide Adenine Dinucleotide) and why it matters for your health.

They explain what NAD does in the body, especially for energy, brain function, and recovery. You’ll hear how NAD levels drop as we age, how alcohol and medications can drain it faster, and the different ways the body makes NAD on its own.

Dr. Anderson also talks about today’s options, from supplements like NMN, NR, and niacinamide to IV therapy. He shares when IVs make sense, when oral forms might be enough, and what to know about side effects and safety, including the common question about NAD and cancer.

This is a straight talk about NAD, what’s real and what’s hype, and how it can support energy, recovery, and long-term wellness.


📌 Dr. Paul Anderson

Dr. Anderson is an esteemed educator and clinician in integrative and naturopathic medicine, focusing on complex infectious, chronic, and oncologic illnesses, with over three decades of clinical experience. He founded Advanced Medical Therapies for cancer and chronic diseases in Seattle, Washington, and still collaborates with various clinics and hospitals. He has held positions at multiple medical schools, including Professor of Pharmacology and Clinical Medicine at Bastyr University. He has authored several books and articles and is actively involved in continuing medical education through online platforms and conferences.


🔗 Learn more about Dr. Paul Anderson

Website: https://dranow.com

Instagram: www.instagram.com/draonline/

Connect with Dr. Greg Jones

Instagram: @doctorjones_doctorjones 

Enovative Wellness Center: https://enovativewellness.com/ 


🔬 Timestamps
00:00 – Welcome back and introduction

02:35 – What NAD is and why it matters

06:00 – Real benefits vs. hype around NAD

10:49 – Why NAD levels drop

12:27 – How aging and stress affect NAD

18:18 – How the body makes its own NAD

22:10 – How NAD gets into cells

28:39 – NAD precursors and how they work

37:39 – Can you test NAD levels?

44:23 – Using tests to guide treatment

47:42 – IV therapy vs. oral supplements

51:29 – Using NAD for health and recovery

55:41 – IV nicotinamide riboside explained

01:01:26 – Side effects and safety concerns

01:11:22 – CD38 and its role in NAD decline

01:14:36 – Do NAD patches actually work?

01:16:26 – Subcutaneous injections vs. IV therapy

01:19:56 – Where NAD therapy is headed


📣 Subscribe + Follow: Don’t miss an episode! Subscribe and leave a review. 📺 YouTube: https://www.youtube.com/@DrJonesNMDTV 🎧 Spotify: https://open.spotify.com/show/2QrMGwCIGo1kjdezfCyYDK?si=WhH4DW3oQw2k9qkfCtHZdQ 
Disclaimer: The information shared on The Dr. Jones Optimization Podcast and its associated YouTube channel is intended for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Listening to this podcast or viewing its content does not create a doctor–patient relationship, and nothing shared should be interpreted as individualized medical guidance. Always consult with a qualified healthcare provider before making changes to your health regimen or managing a medical condition. The opinions expressed by Dr. Jones and his guests are their own and do not reflect official medical advice or recommendations

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1 month ago
1 hour 27 minutes 1 second

Optimization Academy with Dr. Greg Jones
71. Fix Your Sleep, Save Your Life: A Sleep Apnea Deep Dive

In this episode, Dr. Jones is joined by Christina Finnerty, FNP-C—a functional medicine expert specializing in sleep disorders, hormonal health, and regenerative therapies.

Together, they uncover the far-reaching effects of untreated sleep apnea on your brain, heart, metabolism, and even your biological age. Christina shares how obstructive sleep apnea (OSA) accelerates aging, increases the risk of cardiovascular disease, and contributes to cognitive decline and chronic illness.

The conversation also covers practical diagnostics, alternative therapies beyond the CPAP machine, and integrative approaches—including peptides, supplements, and lifestyle interventions—supporting recovery and nervous system regulation.

If you or someone you love struggles with sleep, fatigue, or unexplained symptoms, this episode may provide the missing link.🔗 Learn more about Christina Finnerty, FNP-C Christina Finnerty, FNP-C, provides personalized care for healing, recovery, and wellness, addressing issues like autoimmune disorders, inflammation, pain, brain health, and nervous system concerns. Using advanced testing, including GI mapping, lipid panels, cardiac CT (by referral), and body composition analysis, Christina helps identify the underlying factors of health issues. Christina is passionate about helping patients identify the causes of their health concerns and creating practical, long-term plans to improve wellness, happiness, and longevity.https://ridgelinemedical.org/christin...Christina@ridgelinemedical.orgConnect with Dr. Greg JonesInstagram: @doctorjones_doctorjones Enovative Wellness Center: https://enovativewellness.com/ 🔬 Timestamps

  • Introduction & the story of how the host was diagnosed with sleep apnea. (00:00 - 02:31)
  • Christina's journey into functional medicine and sleep specialization. (02:31 - 05:48)
  • What is sleep apnea and why is it so much more dangerous than just snoring? (05:48 - 09:24)
  • How sleep apnea accelerates cardiovascular and cognitive aging. (09:24 - 13:43)
  • Overlooked signs and symptoms of sleep apnea beyond daytime fatigue. (13:43 - 17:45)
  • How sleep apnea symptoms can differ between men and women. (17:45 - 20:37)
  • The prevalence of undiagnosed sleep apnea. (20:37 - 24:19)
  • Is the cardiovascular and neurological damage from sleep apnea reversible? (24:19 - 25:22)
  • The diagnostic process: Comparing home sleep studies vs. in-lab testing. (25:22 - 28:51)
  • The difference between obstructive sleep apnea and central sleep apnea. (28:51 - 33:40)
  • Treatment options, Part 1: CPAP as the gold standard. (33:40 - 35:54)
  • Treatment options, Part 2: Alternatives like oral appliances, surgery, and implants. (35:54 - 39:40)
  • Treatment options, Part 3: Positional therapy, mouth taping, and adapting to treatment. (39:40 - 45:30)
  • Integrative and functional medicine support (hormones, supplements, peptides). (45:30 - 50:24)
  • Unpacking the complex link between testosterone and sleep apnea. (50:24 - 53:06)
  • Summary of key takeaways and a call to action for patients and providers. (53:06 - 56:23)
  • Closing questions and where to find Christina online. (56:23 - 01:00:15)


📣 Subscribe + Follow: Don’t miss an episode! Subscribe and leave a review. 

📺 YouTube: https://www.youtube.com/@DrJonesNMDTV 

🎧 Spotify: https://open.spotify.com/show/2QrMGwCIGo1kjdezfCyYDK?si=WhH4DW3oQw2k9qkfCtHZdQ  

Disclaimer: The information shared on The Dr. Jones Optimization Podcast and its associated YouTube channel is for informational purposes only. Listening to this podcast or viewing its content does not create a doctor–patient relationship, and nothing shared should be interpreted as individualized medical guidance. Always consult with a qualified healthcare provider before making changes to your health regimen or managing a medical condition. The opinions expressed by Dr. Jones and his guests are their own and do not reflect official medical advice or recommendations.

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2 months ago
1 hour 16 seconds

Optimization Academy with Dr. Greg Jones
70. Testosterone for Women: Benefits, Risks, and BS

In this episode, Dr. Jones is joined by Dr. Lauren Fitzgerald—an anesthesiologist-turned-functional medicine leader—to uncover the myths, science, and clinical pearls around testosterone therapy in women.

They explore why testosterone matters far beyond libido, how symptoms of deficiency often get dismissed or misdiagnosed, and what dosing, delivery, and lab markers really tell us. From estrogen dominance to perimenopause, cognitive function to confidence—this episode reveals how hormone optimization can be a game-changer for women at every stage of life.

Whether you’re a provider or a patient, this conversation offers evidence-backed clarity on a topic too often misunderstood.🔗 Learn more about Dr. Lauren Fitzgerald

https://www.larimarmed.com/https://www.instagram.com/drlaurenfitz/Connect with Dr. Greg JonesInstagram: @doctorjones_doctorjones Enovative Wellness Center: https://enovativewellness.com/ 🔬 Timestamps- Introduction to the episode and guest, Dr. Lauren Fitzgerald. (00:00 - 01:50)- Dr. Fitzgerald's story: Transitioning from anesthesiology to functional medicine. (01:50 - 06:06)- How optimizing her own hormones changed Dr. Fitzgerald's life and medical practice. (06:06 - 08:48)- Why is testosterone important for women, and why is it overlooked in traditional medicine? (08:48 - 13:35)- What are the most common signs and symptoms of low testosterone in women? (13:35 - 16:44)- The role of testosterone in brain function, memory, and mood. (16:44 - 17:40)- What are some surprising benefits of testosterone therapy in women? (17:40 - 19:13)- How often are low testosterone symptoms misdiagnosed or dismissed in women? (19:13 - 21:42)- What labs are essential for diagnosing low testosterone? (21:42 - 23:47)- Addressing common patient fears and side effects of testosterone therapy. (23:47 - 30:26)- Does taking testosterone negatively affect a woman's estrogen balance? (30:26 - 33:35)- Dr. Fitz debunks the top myths about testosterone use in women. (33:35 - 36:25)- Comparing delivery methods: Creams vs. injections vs. pellets. (36:25 - 43:22)- What are the optimal testosterone lab ranges for women? (43:22 - 47:47)- How treatment approaches differ for pre-menopausal, perimenopausal, and post-menopausal women. (47:47 - 49:47)- What does Dr. Fitz wish more women and their partners knew about testosterone? (49:47 - 50:20)- Advice for women on how to talk to their doctors about testosterone. (50:20 - 51:44)- What Dr. Fitz would tell her younger self just out of med school. (51:44 - 52:42)- Where listeners can find and learn more from Dr. Fitzgerald. (52:42 - 53:45)📣 Subscribe + Follow: Don’t miss an episode! Subscribe and leave a review. 📺 YouTube: https://www.youtube.com/@DrJonesNMDTV 🎧 Spotify: https://open.spotify.com/show/2QrMGwCIGo1kjdezfCyYDK?si=WhH4DW3oQw2k9qkfCtHZdQ  Disclaimer: The information shared on The Dr. Jones Optimization Podcast and its associated YouTube channel is intended for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Listening to this podcast or viewing its content does not create a doctor–patient relationship, and nothing shared should be interpreted as individualized medical guidance. Always consult with a qualified healthcare provider before making changes to your health regimen or managing a medical condition. The opinions expressed by Dr. Jones and his guests are their own and do not reflect official medical advice or recommendations.

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3 months ago
53 minutes 46 seconds

Optimization Academy with Dr. Greg Jones
69. Reboot Your Nervous System: Procaine IV Therapy for Pain, Stress, and Inflammation

What if an anesthetic known for dental procedures could have a powerful effect on pain, inflammation, and nervous system regulation? Far beyond a numbing agent, Procaine is now being used as a powerful tool to reset the autonomic nervous system and treat chronic pain and stress at a cellular level.Joining me today is Lexi Yoo, a double board-certified Nurse Practitioner, IFM Certified Practitioner, and the founder of Yoo Direct Health. Learn more: @lexiyooNPYDH Training Academy: https://ydhacademy.com/

In this conversation, we explore: • How Procaine IV works beyond anesthesia to influence the nervous, immune, and inflammatory systems • Why it may be one of the best-kept secrets for patients dealing with chronic stress, autoimmune issues, and lingering trauma • What the clinical research tells us after 20+ years of use in Europe and integrative clinics worldwide • And how to implement Procaine safely and effectively in modern clinical practice.

Catch me at: Instagram: @doctorjones_doctorjones Become a patient: https://enovativewellness.com/ 🔬 Timestamps- Intro: Exploring Procaine for Pain, Inflammation & Nervous System Repair (00:00 - 00:58)- Welcoming Lexi Yu & Catching Up (00:58 - 03:20)- Procaine 101: Resetting the Autonomic Nervous System (03:20 - 06:05)- The "Circuit Breaker" Analogy for Nervous System Regulation (06:05 - 07:16)- Mechanism Explained: Procaine's Metabolites and Their Effects (07:16 - 09:59)- Clinical Relevance: Membrane Stabilization and Sympathetic Tone Reduction (09:59 - 11:09)- Patient Presentation: Who Has a Dysregulated Nervous System? (11:09 - 14:23)- Procaine vs. Ketamine and Pairing with EMDR Therapy (14:23 - 17:51)- Who Benefits Most? Ideal Patient Profiles for Procaine Therapy (17:51 - 19:54)- Contraindications and The "Lightning Response" Emotional Release (19:54 - 22:43)- Understanding "Interference Fields" from Past Traumas and Surgeries (22:43 - 24:29)- Dosing & Protocols: Loading and Maintenance Phases (24:29 - 28:45)- What to Expect: Duration of a Procaine IV Session (28:45 - 30:05)- Tracking Outcomes: Subjective Feedback, Oura Ring & Lab Markers (30:05 - 33:16)- Synergistic Therapies: Pairing Procaine with Ozone, Peptides & Prolozone (33:16 - 36:35)- Using Procaine in Regenerative Aesthetics (Hair & Skin) (36:35 - 37:37)- For Practitioners: Where to Learn More About Procaine Therapy (37:37 - 39:33)- Outro: Where to Find Lexi Yu (39:33 - 40:11)- Dr. Jones' Personal Anecdote: Procaine's Effect on His Oura Ring (40:11 - 41:34)📣 Subscribe + Follow: Don’t miss an episode! Subscribe and leave a review. 📺 YouTube: https://www.youtube.com/@DrJonesNMDTV  Disclaimer: The information shared on The Dr. Jones Optimization Podcast and its associated YouTube channel is intended for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Listening to this podcast or viewing its content does not create a doctor–patient relationship, and nothing shared should be interpreted as individualized medical guidance. Always consult with a qualified healthcare provider before making changes to your health regimen or managing a medical condition. The opinions expressed by Dr. Jones and his guests are their own and do not reflect official medical advice or recommendations

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3 months ago
41 minutes 34 seconds

Optimization Academy with Dr. Greg Jones
68. Stronger, Leaner, Sharper: Meet SLU-PP-332

What if you could mimic the effects of exercise—without actually hitting the gym? In this episode, Dr. Jones sits down with Anthony Castore, one of the most respected performance and cellular medicine coaches in the country, to explore SLU-PP-332, a compound with powerful mitochondrial and metabolic benefits.Anthony is the founder of DRIVE Longevity Solutions and a Fellow of the SSRP Institute. With over 30 years of high-performance coaching and deep knowledge of cellular biology, he brings unmatched insight into how compounds like SLU-PP-332 can be used to optimize athletic performance, body composition, and even organ repair.We dive into ERR receptors, the PGC1α–AMPK–ERR axis, mitochondrial biogenesis, metabolic flexibility, parasympathetic fat burning, neuroprotective effects, and how to titrate dosing for both patients and elite athletes. Whether you're a clinician, biohacker, or fitness enthusiast, this episode is packed with science and strategy you can use.📌 About Anthony CastoreAnthony Castore is the founder of DRIVE Longevity Solutions and a rare non-physician Fellow of the SSRP Institute. Known for his high-integrity science and no-fluff approach, he blends cutting-edge cellular medicine with decades of elite coaching experience. Anthony works with professional athletes, top-tier executives, and forward-thinking clinicians to design precision protocols for performance and long-term health. Learn more: @anthonycastoreThis episode is brought to you by Tides Health: Code DRJONES for 15% off your first order at https://yourtides.com/ Catch me at: Instagram: @doctorjones_doctorjones Become a patient: https://enovativewellness.com/ 🔬 Timestamps- Intro and Meet Anthony Castore (00:00 - 10:30)- Explaining ERR receptors and non-ligand activation (10:30 - 17:08)- SLU-PP-332 as a mitochondrial agent (17:08 - 19:37)- The PGC1α–AMPK–ERRα axis explained (19:37 - 24:47)- Exercise mimetic vs. exercise replacement (24:47 - 25:12)- Synergy with fasting, cold plunges, and HIIT (25:12 - 30:49)- Real-world results: performance, VO₂, recovery, and body comp (30:49 - 34:23)- Skeletal muscle retention and metabolic flexibility (34:23 - 35:42)- Lipolysis in parasympathetic state: a fat-loss breakthrough (35:42 - 36:32)- Timing SLU-PP-332: morning and post-workout protocols (36:32 - 38:31)- Organ system improvements: liver, kidney, A1C (38:31 - 42:45)- Personalized dosing protocols and titration strategy (42:45 - 43:15)- Measuring metabolic flexibility: RER, Lumen, glucose (43:15 - 47:16)- Dosing sweet spots for men vs. women (47:16 - 48:14)- Mitochondrial support stack: CoQ10, carnitine, NAD, NAC, SS-31 (48:14 - 50:22)- Redox balance: how to detect when you’ve gone too far (50:22 - 53:40)- Side effects and estrogen dominance risks (53:40 - 56:28)- Smart protocols vs. reckless stacking (56:28 - 56:50)- Learning more about SLU-PP-332: mechanisms over marketing (56:50 - 59:01)- Anthony’s final advice: curiosity over intensity (59:01 - 01:00:34)- Outro and where to find Anthony (01:00:34 - 01:03:29) 📣 Subscribe + Follow: Don’t miss an episode! Subscribe and leave a review. 📺 YouTube: https://www.youtube.com/@DrJonesNMDTV 🎧 Spotify: https://open.spotify.com/show/2QrMGwCIGo1kjdezfCyYDK?si=WhH4DW3oQw2k9qkfCtHZdQ Disclaimer: The information shared on The Dr. Jones Optimization Podcast and its associated YouTube channel is intended for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Listening to this podcast or viewing its content does not create a doctor–patient relationship, and nothing shared should be interpreted as individualized medical guidance. Always consult with a qualified healthcare provider before making changes to your health regimen or managing a medical condition. The opinions expressed by Dr. Jones and his guests are their own and do not reflect official medical advice or recommendations.

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4 months ago
1 hour 3 minutes 29 seconds

Optimization Academy with Dr. Greg Jones
67. Genetics and Longevity with Dr. Laura Lile

In this episode, I am joined by Dr. Laura Lile — one of the few U.S. physicians dual-credentialed as both a Registered Pharmacist and a Medical Doctor — to explore how genomics is revolutionizing the future of preventative and precision medicine. Dr. Lile shares her journey from pharmacy innovator to longevity-focused clinician and breaks down how our genetic blueprint, when interpreted through tools like IntellxxDNA, can help guide personalized health strategies that optimize brain health, prevent chronic disease, and extend quality of life.

From pioneering drive-thru pharmacies and concierge telehealth to decoding epigenetic influences and SNP variants, this episode is packed with insight, innovation, and clinical application.

🧬 Topics Covered: • Dr. Lile’s path from pharmacy to medicine and the innovation mindset behind it • The difference between genetics and epigenetics • How lifestyle and environment shape gene expression • Using genomics to prevent chronic illness and optimize longevity • Powerful case studies • How IntellxxDNA supports real-world, clinical decision-making • Future of AI in genomic medicine and personalized health plans👤 About Dr. Laura Lile:Dr. Lile is a nationally recognized expert in functional medicine and one of the rare dual-credentialed professionals certified as both a Pharmacist and an MD. She founded Lile Wellness Partners, where she leads a proactive, genomics-informed approach to longevity, brain optimization, and chronic disease prevention. Her expertise is grounded in decades of pharmacy practice, innovation in telehealth and concierge care, and pioneering genomic testing for personalized treatment plans.This episode is brought to you by:Tides Health: Code DRJONES for 15% off your first order at https://yourtides.com/📍 Resources & Links: • Learn more about Dr. Laura Lile: https://lilewellness.com • IntellxxDNA for clinicians and patients: https://lilewellness.com/genomics • Connect with Dr. Lile directly: drlaura@lilewellness.comCatch me at:Instagram: @doctorjones_doctorjonesBecome a patient: https://enovativewellness.com/⏱️ Timestamps:- Intro + Celebrating Mother’s Day (00:00 - 02:52)- Pharmacy to MD: What led Dr. Lile back to medical school (02:52 - 07:45)- Innovating the drive-thru pharmacy at age 25 (07:45 - 09:45)- Concierge telemedicine before it was mainstream (09:45 - 17:16)- Genomics vs. Epigenetics explained (17:16 - 19:13)- Poker, software updates & genetic expression (19:13 - 26:15)- Addressing gene risk without fear: Empowerment through action (26:15 - 31:53)- Barriers clinicians face in learning genomics (31:53 - 35:08)- IntellxxDNA vs. 23andMe: What makes it clinically powerful (35:08 - 41:59)- Real-world case studies: Cancer, Parkinson’s, heart disease (41:59 - 49:19)- Do patients need supplements for life? (49:19 - 51:58)- The role of AI and what excites Dr. Lile about the future (51:58 - 57:46)- Advice Dr. Lile would give her younger self (57:46 - 59:25)📣 Subscribe + Follow:Don’t miss an episode! Subscribe and leave a review.📺 YouTube: https://www.youtube.com/@DrJonesNMDTV🎧 Spotify: https://open.spotify.com/show/2QrMGwCIGo1kjdezfCyYDK?si=WhH4DW3oQw2k9qkfCtHZdQ📸 Instagram: https://www.instagram.com/doctorjones_doctorjones/Disclaimer: The information shared on The Dr. Jones Optimization Podcast and its associated YouTube channel is intended for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Listening to this podcast or viewing its content does not create a doctor–patient relationship, and nothing shared should be interpreted as individualized medical guidance. Always consult with a qualified healthcare provider before making changes to your health regimen or managing a medical condition. The opinions expressed by Dr. Jones and his guests are their own and do not reflect official medical advice or recommendations

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5 months ago
1 hour 1 minute 43 seconds

Optimization Academy with Dr. Greg Jones
66. The Next Frontier of Testosterone Replacement Therapy

In this episode, I’m joined by Shalin Shah, CEO of Marius Pharmaceuticals, to talk about the past, present, and future of testosterone replacement therapy (TRT). From the systemic decline in testosterone levels among younger men to the breakthrough FDA-approved oral testosterone Kyzatrex, this conversation explores what’s next for hormone optimization—and why it matters more than ever.Take a look and listen as we dive deep into the myths around oral testosterone, why SHBG levels matter, how testosterone therapy affects inflammation, cardiovascular risk, cognition, libido, and longevity, and why optimizing free testosterone—not just total T—is the true goal. Plus, we discuss clinical pearls for transitioning from injections or pellets to oral therapy, monitoring labs effectively, and future directions for female testosterone replacement.

Whether you’re a clinician, a patient, or someone interested in living with more energy, drive, and clarity—this episode is a must-listen.🧠 About Shalin Shah:Shalin Shah is the Chief Executive Officer of Marius Pharmaceuticals, a company pioneering innovative therapies to address testosterone deficiency and cardiometabolic disease. With a background in economics, biotech leadership, and healthcare strategy, Shalin has become a leading advocate for rethinking how testosterone is tested, prescribed, and perceived. He’s also the founder of RethinkTestosterone.com, an educational platform for clinicians and patients aiming to shift the paradigm from symptom-based care to proactive, personalized hormone optimization.This episode is brought to you by Tides Health, formulating physician-grade peptide-based supplements designed for performance, recovery, and longevity.🛒 Shop now at yourtides.com — Use code DRJONES for 15% off your first order📍 Resources & Links:• Learn more about Kyzatrex: https://www.kyzatrex.com/• Rethink Testosterone: https://www.rethinktestosterone.com/• 📲 Follow Shalin Shah on Instagram: @TheMetabolicCEO⏱️ TIMESTAMPS:00:00 – Welcome & the testosterone crisis in men01:00 – Meet Shalin Shah: Why testosterone is his mission04:30 – What’s causing the testosterone collapse in younger men?08:15 – Low T symptoms and why “normal” labs can be misleading13:00 – Comparing TRT delivery options: injections, topicals, pellets, and oral16:30 – Why SHBG matters more than you think22:00 – Kyzatrex: Oral testosterone that bypasses the liver26:00 – The importance of dietary fat for oral testosterone absorption33:00 – Estrogen management and why most men don’t need AIs38:00 – TRT and fertility: What the Kyzatrex trials reveal41:00 – How to transition from other TRT forms to oral43:00 – Best practices for lab testing Kyzatrex44:30 – How testosterone affects inflammation, cardiovascular risk & longevity46:00 – Future of TRT for women48:00 – What Shalin would tell his younger self49:00 – Where to learn more about Kyzatrex, Marius, and TRT science📣 Subscribe + Follow:Don’t miss an episode! Subscribe and leave a review.📺 YouTube: https://www.youtube.com/@DrJonesNMDTV🎧 Spotify: https://open.spotify.com/show/2QrMGwCIGo1kjdezfCyYDK?si=WhH4DW3oQw2k9qkfCtHZdQDisclaimer: The information shared on The Dr. Jones Optimization Podcast and its associated YouTube channel is intended for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Listening to this podcast or viewing its content does not create a doctor–patient relationship, and nothing shared should be interpreted as individualized medical guidance. Always consult with a qualified healthcare provider before making changes to your health regimen or managing a medical condition. The opinions expressed by Dr. Jones and his guests are their own and do not reflect official medical advice or recommendations

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5 months ago
51 minutes 8 seconds

Optimization Academy with Dr. Greg Jones
65. The Future of Medicine is Now: Peptide Therapy with Dr. Elena Zinkov

Welcome back to The Dr. Jones Optimization Academy Podcast! In this episode, we're joined by the incredible Dr. Elena Zinkov, a trailblazer in women’s health and a leader in personalized medicine. We dive into how peptide therapy can be used to address three of the most common concerns patients bring to functional and naturopathic physicians: pain, fatigue, and gut health.As founder of Proactive Health ND, Dr. Zinkov is transforming how women experience medicine. In this episode, we break down how she integrates peptides into care, what barriers exist to access and prescribing, and how she tracks outcomes with a therapeutic order that always starts with foundations.Whether you’re a patient curious about how peptides might help you, or a practitioner looking for insights into peptide integration, this episode is packed with clinical gems and real-life experience.✅ Why peptide therapy is not taught in medical school—and why that needs to change✅ How peptides work in the body and why they’re often safer than traditional medications✅ Which peptides Dr. Zinkov uses most often in real-world clinical scenarios✅ The biggest myths and misconceptions patients and practitioners have about peptides✅ How to think about peptides in the therapeutic order—and who should not be using them🔔 Don’t forget to like, comment, and subscribe for more expert insights on longevity, peptides, and women’s health! ⏳ Episode Chapters & Timestamps- Intro (00:00 - 03:12)- Dr. Zinkoff’s Journey into Longevity & Cellular Medicine (03:12 - 04:29)- Personal Health Story: Autoimmunity, Postpartum, and Peptides (04:29 - 09:05)- What Are Peptides and How Do They Work in the Body? (09:05 - 09:10)- Why Peptides Tend to Have Fewer Side Effects (09:10 - 12:19)- Barriers to Accessing Peptides as a Patient (12:19 - 13:15)- Barriers to Prescribing Peptides as a Practitioner (13:15 - 20:42)- The Problem with Research Peptides & Online Sources (20:42 - 25:36)- Who Benefits Most from Peptides? (25:36 - 29:50)- Who Should *Not* Be Using Peptides? (29:50 - 36:14)- The Big Three: Peptides for Pain, Fatigue, and Gut Health (Setup) (36:14 - 36:42)- Peptides for Pain (36:42 - 39:02)- Peptides for Fatigue (39:02 - 39:52)- Peptides for Gut Health (39:52 - 41:28)- Glutathione as a Peptide & Its Role in Pain & Inflammation (41:28 - 43:38)- TB-500 vs Thymosin Beta-4: What's the Difference? (43:38 - 45:30)- The Energy Puzzle: Sleep, Recovery, and Hormone Balance (45:30 - 46:40)- Myths & Misconceptions: Cancer, Steroids, and Misinformation (46:40 - 52:08)- Where to Find Dr. Zinkoff & Her Work (52:08 - 53:33) 🔗 Connect with Dr. Elena Zinkov🌐 Website: proactivehealthnd.com📸 Instagram: @drelenazinkov💬 What was your biggest takeaway from this episode? Drop a comment below!🚀 For more episodes on peptide therapy, women’s health, and longevity, hit that SUBSCRIBE button!Disclaimer: The information shared on The Dr. Jones Optimization Podcast and its associated YouTube channel is intended for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Listening to this podcast or viewing its content does not create a doctor–patient relationship, and nothing shared should be interpreted as individualized medical guidance. Always consult with a qualified healthcare provider before making changes to your health regimen or managing a medical condition. The opinions expressed by Dr. Jones and his guests are their own and do not reflect official medical advice or recommendations

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6 months ago
53 minutes 33 seconds

Optimization Academy with Dr. Greg Jones
64. Deflating High Blood Pressure: A Functional Medicine Approach with Dr. Abid Husain

Hypertension is known as the ‘silent killer,’ but what if I told you it’s NOT just about cholesterol or genetics? Today, we’re diving deep into hypertension, heart disease, and how a functional medicine approach can transform cardiovascular health. My guest, Dr. Abid Husain, MD, FACC, ABAARM, FSSRP, is a board-certified cardiologist who integrates cellular medicine, hormone optimization, and cutting-edge therapies to address the real root causes of cardiovascular disease.In this episode, we break down:✅ The true causes of high blood pressure (hint: it’s more than just salt and stress!)✅ The best exercise strategies proven to lower blood pressure✅ How hormones, peptides, and GLP-1 receptor agonists play a major role in cardiovascular health✅ Supplements that help – and some that you might want to avoid✅ Why inflammation and oxidative stress are the real threats to your heart💡 If you're looking to optimize your cardiovascular health with a functional approach, this episode is a must-watch!- Intro (00:00 - 00:48)- Breaking Away from Conventional Cardiology | What Led Dr. Husain to Functional & Cellular Medicine (00:48 - 07:30)- Why Heart Disease Is More Than Just Cholesterol | The Real Causes of Atherosclerosis (07:30 - 14:00)- Hypertension: The Silent Killer | Why High Blood Pressure Is So Dangerous (14:00 - 18:24)- How Functional Medicine Labs & Imaging Can Identify At-Risk Patients (18:24 - 28:33)- Inflammation & Oxidative Stress | The Cellular Triggers of High Blood Pressure (28:33 - 32:50)- Hormones & Cardiovascular Health | The Link Between Testosterone, Estradiol, and Heart Disease (32:50 - 38:55)- Exercise for Blood Pressure | The Best Workouts for Heart Health (Isometric Training, HIIT, Strength) (38:55 - 45:06)- The Sleep-Heart Connection | Why Poor Sleep Wrecks Blood Pressure (45:06 - 47:52)- Alcohol & Blood Pressure | The Shocking Link You Need to Know (47:52 - 49:43)- Top Supplements for Cardiovascular Health | What Works & What to Avoid (49:43 - 57:22)- GLP-1 Receptor Agonists & Heart Health | How Medications Like Semaglutide Lower Blood Pressure (57:22 - 1:01:51)- Peptides for Heart Health | The Most Promising Longevity & Cardiovascular Peptides (1:01:51 - 1:04:40)- Future of Cardiovascular Medicine | AI, Imaging, & Cutting-Edge Research (1:04:40 - 1:08:47)- Final Thoughts & Where to Find Dr. Husain (1:08:47 - 1:10:50)💬 What was your biggest takeaway from this episode? Drop a comment below!🚀 For more episodes on longevity and optimizing your health, hit that SUBSCRIBE button!🌐 Learn More: 🔗 Dr. Husain at Boulder Longevity Institute: https://boulderlongevity.com/about 🔗 Dr. Husain’s art: http://www.movementandcolor.com/ 🔗 Follow Dr. Husain on Instagram: https://www.instagram.com/ahusain666/🔗 Connect with Dr. Jones on Instagram: https://www.instagram.com/doctorjones_doctorjones/

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7 months ago
1 hour 10 minutes 50 seconds

Optimization Academy with Dr. Greg Jones
63. The Powerhouses of Longevity: Mitochondrial Optimization with Dr. Elizabeth Yurth

Mitochondria are the powerhouse of the cell, but their role in longevity and overall health goes far beyond energy production. When mitochondrial function declines, it contributes to aging, inflammation, and chronic disease. In this episode, I am excited to welcome back Dr. Elizabeth Yurth to break down why mitochondria are at the root of longevity, how to optimize mitochondrial function, and the best peptides, supplements, and lifestyle strategies to support cellular health.

Dr. Elizabeth Yurth, MD, is a board-certified specialist in longevity, regenerative medicine, and orthopedics, as well as the co-founder and medical director of the Boulder Longevity Institute. She’s a leading expert in peptide therapy, cellular medicine, and age-related disease prevention.- Intro (00:00 - 00:57)- Dr. Elizabeth Yurth’s recent work in cellular medicine (00:57 - 04:34)- Why mitochondria are essential for energy and longevity (04:34 - 07:05)- Mitochondria and hormone production: The overlooked connection (07:05 - 08:20)- Mitochondrial dysfunction: The root cause of chronic disease (08:20 - 11:24)- How mitochondrial dysfunction leads to inflammation & oxidative stress (11:24 - 17:33)- Top signs & symptoms of mitochondrial dysfunction (17:33 - 24:31)- Environmental factors that damage mitochondria (toxins, stress, diet, etc.) (24:31 - 31:31)- Can we test for mitochondrial health? Biomarkers & lab tests (31:31 - 39:00)- How lifestyle impacts mitochondria: Fasting, exercise, red light therapy (39:00 - 45:15)- Best supplements for mitochondria: NAD, CoQ10, 1-MNA, creatine - and are NAD precursors like NMN & NR actually beneficial? (45:15 - 48:39)- Ketones & creatine: The ultimate mitochondrial enhancers (48:39 - 55:33)- Mitochondrial peptides: SS-31, Humanin, 5-Amino-1MQ & more (55:33 - 01:01:56)- How SS-31 repairs mitochondrial membranes & boosts energy (01:01:56 - 01:09:53)- The future of mitochondrial medicine: Mitochondrial uncouplers & new peptides (01:09:53 - 01:14:48)- Dr. Yurth’s biggest lesson on longevity & cellular medicine (01:14:48 - 01:18:08)- Where to find Dr. Yurth & learn more about mitochondrial health (01:18:08 - 01:18:30)🌐 Learn More:

🔗 Boulder Longevity Institute: https://boulderlongevity.com/

🔗 BLI Academy (for physician education): https://bli.academy

🔗 Follow Dr. Yurth on Instagram: https://www.instagram.com/dryurth/🔗 Connect with Dr. Jones on Instagram: https://www.instagram.com/doctorjones_doctorjones/

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7 months ago
1 hour 19 minutes 42 seconds

Optimization Academy with Dr. Greg Jones
62. The Leaky Gut Breakdown with Dr. Ilana Gurevich

In this episode, Dr. Jones dives deep into gut health with the incredible Dr. Ilana Gurevich, a naturopathic gastroenterologist and expert in functional medicine. With decades of experience treating complex GI cases, Dr. Gurevich shares her personal journey with Crohn’s disease, how it shaped her career, and her unique approach to healing leaky gut, addressing autoimmunity, and optimizing overall gut health. You’ll learn why leaky gut is more than just a buzzword, how the gut impacts everything from autoimmunity to mental health, and actionable strategies for restoring gut integrity. Don’t miss this insightful conversation—it’s packed with real-world advice for both patients and practitioners! - Introduction (00:00 - 01:33)- Dr. Gurevich’s Journey: From personal Crohn’s struggles to becoming a gut health specialist. (01:33 - 06:43)- Naturopathic Gastroenterology vs. Conventional Care: The key differences and benefits. (06:43 - 08:33)- Why Gut Health Matters: Addressing IBS, IBD, and other common conditions. (08:33 - 09:58)- Turd Nerds Podcast: Dr. Gurevich’s passion project for sharing clinical insights. (09:58 - 14:38)- What is Leaky Gut?: The science behind intestinal permeability. (14:38 - 20:16)- Triggers for Leaky Gut: Stress, toxins, medications, and diet. (20:16 - 22:56)- The Role of Processed Foods: How modern diets impact gut health. (22:56 - 27:33)- Stress and the Gut-Brain Connection: Why stress is a major player in GI issues. (27:33 - 29:30)- Signs and Symptoms of Leaky Gut: From bloating to brain fog and beyond. (29:30 - 30:41)- Autoimmune Links: How gut permeability contributes to chronic conditions. (30:41 - 35:37)- Testing for Leaky Gut: Zonulin, LPS, and microbiome assessments. (35:37 - 41:07)- Healing the Gut: Dietary changes, fermented foods, and key nutraceuticals. (41:07 - 44:49)- The “Sinister Six” Foods to Avoid: Gluten, sugar, dairy, and more. (44:49 - 47:51)- Peptides for Gut Health: BPC-157, KPV, and their healing potential. (47:51 - 57:39)- Lifestyle Matters: Why healing doesn’t stop after treatment. (57:39 - 58:49)- Why Maintenance is Key: Practical tips for long-term gut health. (58:49 - 01:01:10)- Closing Thoughts (01:01:10 - 01:08:10) ***** Learn more about Dr. Gurevich: https://www.openwellnesspdx.com/ *****The Turd Nerds podcast: https://podcasts.apple.com/gb/podcast/the-turd-nerds/id1651253399 *****Tides Health: https://yourtides.com/ *****NuBioAge: https://nubioage.com/ *****Connect with Dr. Jones on Instagram: https://www.instagram.com/doctorjones_doctorjones/

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8 months ago
1 hour 8 minutes 11 seconds

Optimization Academy with Dr. Greg Jones
61. Methylene Blue 101

Ready to level up your health? In this exciting episode, we’re diving deep into the world of methylene blue—a game-changing compound with massive potential for brain health, energy production, and anti-aging. Joining me is Dr. Hayden Collier, PharmD, Director of Clinical Services at NuBioAge. Known for his expertise in sports science, integrative medicine, and cutting-edge therapies, Dr. Collier takes us on a journey into the science and practical uses of methylene blue. This is more than a podcast—it’s your ultimate guide to unlocking mitochondrial power, reducing oxidative stress, and achieving next-level health and longevity. Whether you're a healthcare pro or a health optimization enthusiast, this one’s for you! - Introduction (00:00 - 01:20) - Dr. Collier’s journey from traditional pharmacy to integrative medicine (01:20 - 05:57) - The history of methylene blue: From textile dye to medical breakthrough (05:57 - 08:16) - Mitochondrial function 101: Why methylene blue is unique (08:16 - 12:46) - Redox reactions and electron transport chains explained (12:46 - 16:30) - The brain benefits: Cognitive enhancement and neuroprotection (16:30 - 17:58) - Methylene blue’s potential for Alzheimer’s and Parkinson’s (17:58 - 23:58) - Anti-aging applications: Fighting oxidative stress and inflammation (23:58 - 26:47) - Clinical uses: Mood disorders, long COVID, and UTI prevention (26:47 - 33:04) - Skin and wound healing: A surprising benefit of methylene blue (33:04 - 40:43) - Combining methylene blue with red light therapy and other synergistic approaches (40:43 - 42:08) - Methylene blue vs. NAD+: Which one is right for you? (42:08 - 48:17) - Dosage tips, side effects, and why pharmaceutical-grade matters (48:17 - 01:00:02) - Closing thoughts: Why methylene blue is a must-have for longevity protocols (01:00:02 - 01:07:25) ***** Learn more about Dr. Collier and NuBioage:   https://www.instagram.com/haydencollier_pharmd/ https://nubioage.com/ *****Connect with Dr. Jones on Instagram: https://www.instagram.com/doctorjones_doctorjones/           *****Connect with Enovative Wellness Center on Facebook: https://www.facebook.com/GregJonesNMD

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10 months ago
1 hour 7 minutes 25 seconds

Optimization Academy with Dr. Greg Jones
60. Low Dose Naltrexone and Ketamine: Healing the Body and Mind with Sahar Swidan, PharmD

In today’s episode, I am joined by the incredible Sahar Swidan, PharmD, a pioneer in integrative and functional medicine. Dr. Swidan is President and CEO of NeuroPharm and Former CEO of Pharmacy Solutions in Ann Arbor, MI and Adjunct Associate Professor of Clinical Research and Leadership at George Washington University School of Medicine and Health Sciences, and Adjunct Clinical Associate Professor of Pharmacy at Wayne State University. She is an internationally renowned speaker in the areas of pain management, headaches, and HRT. She has authored several book chapters, articles, and patient education material in head and general pain management and personalized medicine.    In this talk, we explored the transformative power of combining East and West medicine, the mechanisms behind low-dose naltrexone (LDN), and its applications in autoimmune diseases, inflammatory conditions, and beyond. Plus, we dove into the burgeoning use of ketamine in mental health and pain management.  Today’s Topics: - Intro (00:00 - 01:58) - Dr. Swidan's Journey: From academia to integrative medicine.(01:58 - 03:00) - East Meets West: The magic of combining traditional and functional medicine.(03:00 - 05:58) - Crunchy Munchy vs. Allopathic Medicine: Why balance is key.(05:58 - 12:43) - Low-Dose Naltrexone (LDN): What it is and how it works.(12:43 - 17:27) - Immune Modulation with LDN: Balancing TH1, TH2, and histamine pathways.(17:27 - 24:58) - Inflammation and Autoimmune Conditions: How LDN helps.(24:58 - 29:26) - LDN as a Gerotherapeutic: Slowing down inflammation-driven aging.(29:26 - 35:57) - LDN for Crohn's Disease and IBD: Real results and gut healing.(35:57 - 43:03) - LDN and Hashimoto’s: Reducing antibodies and improving thyroid function.(43:03 - 46:34) - Ketamine in Medicine: Treating depression, PTSD, and chronic pain. (46:34 - 48:22) - Rapid Antidepressant Effects: Why ketamine works so fast.(48:22 - 53:53) - Ketamine for Fibromyalgia: A potential game-changer.(53:53 - 01:06:36) - Ketamine Risks and Safety: What patients and clinicians need to know. (01:06:36 - 01:18:17) ***** Learn more about Dr. Swidan: https://sahar.world/     *****Connect with Dr. Jones on Instagram: https://www.instagram.com/doctorjones_doctorjones/         *****Connect with Enovative Wellness Center on Facebook: https://www.facebook.com/GregJonesNMD

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10 months ago
1 hour 18 minutes 16 seconds

Optimization Academy with Dr. Greg Jones
59. The Intermittent Fasting Breakdown with Dr. Stephen Anton

In this episode we’re diving into the fascinating world of intermittent fasting. We’ve all heard about the potential benefits of fasting, but what does the science really say? To help us unpack this, we’re joined by Dr. Stephen Anton, professor, researcher, and author. Dr. Anton has studied the fields of obesity, metabolism, and aging for the past 20 years and is world renowned for studying the effects of intermittent fasting on health, fitness, and longevity. Dr. Anton is an expert on various fasting methods, how fasting can boost brain health, support muscle building, and even strengthen the immune system. In this episode, we’ll explore fasting protocols, debunk common myths, and learn how you can start integrating fasting into your own health routine. Today’s Topics: • Intro (00:00 - 07:02) • What is intermittent fasting? (07:02 - 12:36) • 16:8 Intermittent Fasting (12:36 - 26:07) • 18:6 Intermittent Fasting (26:07 - 31:14) • 20:4 and 5/2 Intermittent Fasting (31:14 - 42:17) • How intermittent fasting can support muscle gain and recovery, and tips for timing workouts and meals. (42:17 - 50:49) • Intermittent Fasting for Longevity (50:49 - 57:01) • Does coffee break a fast? (57:01 - 01:00:39) • Best practices for breaking a fast (01:00:39 - 01:05:23) • Debunking Fasting Myths (01:05:23 - 01:13:58) ***** Learn more about Dr. Anton:  https://drstephenanton.com/ https://www.instagram.com/drstephenanton/     *****Connect with Dr. Jones on Instagram: https://www.instagram.com/doctorjones_doctorjones/         *****Connect with Enovative Wellness Center on Facebook: https://www.facebook.com/GregJonesNMD

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10 months ago
1 hour 13 minutes 59 seconds

Optimization Academy with Dr. Greg Jones
58. Peptides and More: An Integrative Approach for Healing and Pain Relief

In this episode of Optimization Academy Podcast, we’re joined by Dr. Morris and Dr. Asare B. Christian, two experts in integrative and regenerative medicine, who are transforming pain management with innovative approaches. From peptide therapies to regenerative injections, we’re exploring the latest tools that help patients find relief and heal at a deeper level. Today’s Topics - Meet Dr. Morris and Dr. Christian and hear how they transitioned from traditional to functional medicine, bringing new hope to patients dealing with pain and chronic conditions. (00:00 - 11:02) - Acute vs. Chronic Pain: The importance of understanding different types of pain and how it impacts treatment strategies, especially regarding inflammation management. (11:02 - 23:15) - When to consider imaging in chronic pain patients and how these results guide personalized treatment plans. (23:16 - 31:57) - Dr. Morris and Dr. Christian share their top lifestyle adjustments for reducing pain and inflammation naturally. (31:58 - 41:57) - Peptides for Pain Relief and Healing: A deep dive into peptides like Thymosin beta-4, Thymosin alpha-1, Pentadecapeptide Arginate (PDA), Pentosan Polysulfate, and CJC-1295/Ipamorelin, and how they support pain relief, recovery, and tissue repair. (41:58 - 1:09:32) Tune in for practical insights, cutting-edge therapies, and a fresh perspective on managing pain and inflammation. Whether you’re a physician, wellness enthusiast, or someone exploring options for chronic pain, this episode has something for you! As always, thanks for tuning in! ***** Learn more about Dr. Christian: https://www.aethermedicine.com/who-we-are/doctor-christian/ ***** Learn more about Dr. Morris: https://www.amgmedicaltucson.com/ *****Click here to subscribe to our YouTube channel: https://www.youtube.com/channel/UCM2Jjqb7MqtZ7VDIuRjguLA/?sub_confirmation=1 *****Connect with Dr. Jones on Instagram: https://www.instagram.com/doctorjones_doctorjones/ *****Connect with Enovative Wellness Center on Facebook: https://www.facebook.com/GregJonesNMD

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11 months ago
1 hour 14 minutes 15 seconds

Optimization Academy with Dr. Greg Jones
57. Beyond Hot Flashes: Estrogen and Longevity

Menopause is defined as the point in a woman’s life when menstrual cycles cease, and it’s no secret that most menopausal symptoms can be relieved by bioidentical estrogen replacement. But estrogen also has essential roles in longevity and reducing the risk of heart disease. To help us break it all down, we’re joined by Dr. Cassie Smith, a board-certified endocrinologist and the founder of Modern Endocrine. Dr. Smith specializes in personalized hormone replacement therapy and helps her patients achieve balance and wellness. Today, she’ll share how optimizing estradiol can not only relieve symptoms but also improve long-term health. Today’s Topics • Intro (00:00 - 09:55) • Understanding the monthly fluctuations of estradiol in the menstrual cycle (09:55 - 20:28) • How hormone levels shift during perimenopause? (20:28 - 26:35) • What are the common symptoms of estrogen deficiency? (26:35 - 33:33) • The broader health benefits of estradiol, including its effects on heart, bone, and brain health. (33:33 - 40:44) • Exploring the pros and cons of various methods of estradiol replacement (patches, pills, creams, etc.). (40:44 - 48:26) • The importance of balancing progesterone with estradiol for safe and effective hormone replacement therapy. (48:26 - 52:58) • Key takeaways on estradiol optimization in menopausal women. (52:58 - 56:27) As always, thanks for tuning in! ***** Learn more about Dr. Smith: https://www.modern-endocrine.com/about *****Click here to subscribe to our YouTube channel: https://www.youtube.com/channel/UCM2Jjqb7MqtZ7VDIuRjguLA/?sub_confirmation=1     *****Connect with Dr. Jones on Instagram: https://www.instagram.com/doctorjones_doctorjones/   *****Connect with Enovative Wellness Center on Facebook: https://www.facebook.com/GregJonesNMD

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1 year ago
56 minutes 27 seconds

Optimization Academy with Dr. Greg Jones
56. Cagrilintide: The Newest Wave in Weight Loss

Obesity is an epidemic and is kerosine to the fire of chronic disease. We all should know to start fighting obesity with diet and exercise, but can injectable peptides be the not-so-secret weapon. Today, we delve deep into a promising candidate—Cagrilintide. This peptide has captured the attention of experts and patients alike, offering new hope through innovative mechanisms that curtail appetite and enhance weight loss. Returning to the show is Dr. Kris Wusterhausen, a seasoned Family Practice Physician and a pioneer in Age Management Medicine. At The Resurge Clinic in Weatherford, Texas, Dr. Wusterhausen is at the forefront of integrating cutting-edge treatments to empower individuals in their health journeys. Today, he'll help us unpack the science behind cagrilintide, its synergies with medications like semaglutide, its standalone potential, and the crucial aspects of its safety and efficacy. Let’s discover if cagrilintide is the missing piece in the ongoing quest to redefine weight management strategies.  Today’s Topics - Intro (00:00 - 03:44) - What is Cagrilintide? (03:44 - 04:50) - How does Cagrilintide work in the body? (04:50 - 11:42) - Can Cagrilintide be used by itself for weight loss? (11:42 - 14:28) - Cagrilintide’s synergistic effects with semaglutide (14:28 - 22:09) - Can cagrilintide be used with tirzepatide? (22:09 - 24:05) - Common and potential side effects of Cagrilintide (24:05 - 27:16) - Discussion on contraindications, similar to semaglutide or unique to Cagrilintide (27:16 - 32:03) - Dr. Wusterhausen's insights on future peptides for weight loss/metabolism (32:03 - 37:14) As always, thanks for tuning in!     ***** Learn more about Dr. Wusterhausen: https://theresurgeclinic.com/about and https://drkris.life/ *****Click here to subscribe to my channel:  https://www.youtube.com/channel/UCM2Jjqb7MqtZ7VDIuRjguLA/?sub_confirmation=1 *****Connect with me on Instagram: https://www.instagram.com/doctorjones_doctorjones/  *****Connect on Facebook: https://www.facebook.com/GregJonesNMD

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1 year ago
37 minutes 13 seconds

Optimization Academy with Dr. Greg Jones
55. Akkermansia: Revolutionizing Gut Health and Metabolism

In this episode, we are diving into the transformative world of gut heath with a focus on the keystone gut bacteria: Akkermansia. Here to help us learn more about Akkermansia is my guest, Christina O’Connor, RD. Christina is a registered dietitian with a rich background in microbiome science. From her early days in pediatrics to her current role at Pendulum Therapeutics, Christina has been a passionate advocate for understanding and harnessing the power of the microbiome to improve health outcomes. Stay tuned as we explore everything from the basics of Akkermansia to advanced applications in dietary practices and healthcare Today’s Topics: • What is Akkermansia? (00:00 - 17:38) • Why are polyphenols necessary for Akkermansia to work optimally? (17:38 - 20:16) • What causes low levels of Akkermansia in the gut and what are the symptoms? (20:16 - 25:25) • Benefits of Akkermansia supplementation and optimizing Akkermansia (25:25 - 28:51) • Is there a difference between pasteurized and live Akkermansia supplements? (28:51 - 35:41) • Pendulum's New Akkermansia Supplements: Metabolic Daily and GLP-1 Probiotic (35:41 - 46:54) As always, thanks for tuning in! *****Learn More about Akkermansia and Pendulum Therapeutics: https://pendulumlife.com/ *****Click here to subscribe to my channel: https://www.youtube.com/channel/UCM2Jjqb7MqtZ7VDIuRjguLA/?sub_confirmation=1     *****Connect with me on Instagram: https://www.instagram.com/doctorjones_doctorjones/     *****Connect on Facebook: https://www.facebook.com/GregJonesNMD

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1 year ago
46 minutes 54 seconds

Optimization Academy with Dr. Greg Jones
Welcome to the Optimization Academy Podcast! Here I will be interviewing some of my favorite innovators in the health care industry and beyond. We will be sharing tips and information on how to become the most powerful version of yourself using naturopathic and integrative medicine, fitness, nutrition, and more. Together we will give you the tools to be informed and empowered! Dr. Greg Jones is Naturopathic Physician, Navy Vet, Reformed Engineer, and Grumpy Dog Dad. His mission in medicine is to shift the conversation away from "sick" care to true healthiness and wellness.