Drs. Greg Simon and Lorella Palazzo discuss their recent Living Textbook Chapter, "End-of-Trial Decision-Making." Read the chapter: https://rethinkingclinicaltrials.org/chapters/dissemination/end-of-trial-decision-making/introduction-end-of-trial-decision-making/

Drs. Pearl O'Rourke and David Wendler discuss their recent publication, "Disentangling Informing Participants From Obtaining Their Consent."

Drs. Lesley Curtis and Keith Marsolo discuss the new learning module "Healthcare Data Interoperability and Standardization for Research."

Drs. Rich Platt, Hayden Bosworth, and Greg Simon consider how to make pragmatic trials more pragmatic.

Dr. James Tulsky and Dr. Angelo Volandes discuss "Advance Care Planning: Promoting Effective and Aligned Communication in the Elderly," also known as the ACP PEACE trial.

Dr. Pearl O'Rourke and Dr. Stephanie Morain discuss waiver or alteration of informed consent for minimal risk clinical investigations.

Dr. Michael Pencina and Dr. Brian Anderson discuss Public-Private Partnerships in the Trustworthy Health AI Ecosystem.

Dr. Harlan M. Krumholz and the PaxLC research team discuss Digital, Decentralized and Democratized: Lessons From The Yale PaxLC Trial.

Dr. Julie Fritz discusses "BeatPain Utah: Partnering with Community Health Centers Within a Socio-Technical Framework."

Dr. Joshua Denny discusses the All of Us Research Program: Improving Health Through Diverse Technology, Huge Cohorts, and Precision Medicine.

Drs. Russell Rothman and Erin Holve discuss a decade of research in PCORnet®.

Dr. Michael Gibson discusses The Heartline Trial and a new paradigm in conducting virtual clinical trials.

This podcast continues the discussion with Dr. Emily Largent as she discusses ethical considerations for vulnerable populations participating in pragmatic clinical trials.

Dr. John Concato discusses the 2021 FDA draft guidance on real-world evidence.

Dr. Christopher Lindsell discusses research outcomes and the importance of choosing the correct outcome.

This podcast continues the discussion with Diana Berrent, JD, and Nick Guthe, founder and member of Survivor Corps, and Natalie Lambert, PhD, of the Indiana University School of Medicine, as they describe best practices for medical professionals treating patients experiencing debilitating effects of COVID-19.

Dr. Boineau moderates a discussion with Drs. Chambers, Curtis, O'Brien, Weber, and Zimmerman about increasing diverse participation in pragmatic clinical trials.

This podcast continues the discussion with Dr. Adrian Hernandez and Dr. Megan L. Ranney about using digital technologies in clinical trials and best practices for online participant recruitment.

In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez speaks with Dr. Susan Ellenberg of the University of Pennsylvania about the challenges encountered by the Data and Safety Monitoring Board overseeing a group of COVID-19 vaccine trials under the National Institutes of Health.

In this episode of the NIH Collaboratory Grand Rounds podcast, Dr. Adrian Hernandez speaks with Dr. Kevin Schulman of Stanford about strategies for promoting widespread COVID-19 vaccination in the United States.