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Let's Talk About Women
Franziska Weinmar
27 episodes
2 weeks ago

“Let’s Talk About Women” is a podcast initiative of the International Research Training Group (IRTG) 2804 (Tübingen x Uppsala), which investigates women's mental health across the reproductive lifespan.

Here we share insights from interdisciplinary research on women's mental health by talking to experts in fields of neuroscience, psychology, biology, and medicine. Beyond that, we will shed light on ongoing doctoral projects among our PhD candidates to get a glimpse into state-of-the-art and hot-topic research.

This podcast is not only for fellow researchers inside and outside the area of women's mental health, but also for people interested in science and curious about this topic!


Do you have any feedback, suggestions, or questions? Get in touch with us: irtg2804.podcast@gmail.com

Are you intrigued by this topic and want to be kept updated? Follow us on twitter: @irtg2804 or instagram: @irtg2804


Hosted on Acast. See acast.com/privacy for more information.

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Science
Education
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All content for Let's Talk About Women is the property of Franziska Weinmar and is served directly from their servers with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.

“Let’s Talk About Women” is a podcast initiative of the International Research Training Group (IRTG) 2804 (Tübingen x Uppsala), which investigates women's mental health across the reproductive lifespan.

Here we share insights from interdisciplinary research on women's mental health by talking to experts in fields of neuroscience, psychology, biology, and medicine. Beyond that, we will shed light on ongoing doctoral projects among our PhD candidates to get a glimpse into state-of-the-art and hot-topic research.

This podcast is not only for fellow researchers inside and outside the area of women's mental health, but also for people interested in science and curious about this topic!


Do you have any feedback, suggestions, or questions? Get in touch with us: irtg2804.podcast@gmail.com

Are you intrigued by this topic and want to be kept updated? Follow us on twitter: @irtg2804 or instagram: @irtg2804


Hosted on Acast. See acast.com/privacy for more information.

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Science
Education
Episodes (20/27)
Let's Talk About Women
Let's Talk With Young Researchers: Romina Garcia de leon

Let's Talk WITH Young Researchers: our podcast sideline in which we give the word to young researchers in the field of women's mental health!


In this episode, meet Romina Garcia de leon, PhD researcher at the Institute of Medical Sciences at the University of Toronto and part of the Laboratory of Behavioural Neuroendocrinology at the Centre for Addiction and Mental Health in Toronto, where she works under the supervision of the one-and-only Dr. Liisa Galea.


We discuss Romina's preclinical research on the heterogeneity of peripartum depression and the role hormones and immune signaling play - including in treatment. Romina also speaks openly about the challenges of pursuing a PhD, but also about what she loves about it. At the end of the podcast, Romina answers our renowned "3 burning questions":

  • Who is your science crush? 
  • What did you not know/expect before starting a PhD? 
  • What do you enjoy most about your work as a PhD researcher? 


Do you want to get in touch with Romina? Reach out to: Romina.Garcia@camh.ca

... or find her here:

  • https://www.galealab.com/rominagarcia
  • https://womenshealthresearchcluster.com/profile/romina-garcia-de-leon/
  • https://www.linkedin.com/in/romina-garcia-de-leon-7b2976149/


Sound recording: Franziska Weinmar

Editing: Franziska Weinmar


Do you have any feedback, suggestions, or questions? Get in touch with us: irtg2804.podcast@gmail.com

Are you intrigued by this topic and want to be kept updated? Follow us on twitter: @irtg2804 or instagram: @irtg2804


Hosted on Acast. See acast.com/privacy for more information.

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2 weeks ago
45 minutes 34 seconds

Let's Talk About Women
Let's Talk About Metabolism

How are metabolism, cognition, mood, and overall health connected - and do these interactions differ between women and men across the lifespan?


In this episode, Franziska talks to Prof. Manfred Hallschmid from the University of Tübingen, where he researches the links between brain function, metabolic processes, and sleep.

Manfred explains how our brain and body communicate when it comes to food intake and mental well-being - and how these processes shift during major hormonal transition phases such as puberty, pregnancy, and menopause. What role do sex hormones play in these changes?

In the outlook, Manfred shares the key questions he believes the field needs to tackle next and what’s the one thing he wishes more people understood about metabolism and well-being.


The topic of metabolism has never been this fascinating - join us as Manfred connects the dots of food intake, hormones, and mental health across the lifespan.


If you would like to get in touch with Manfred, you can find him here: https://www.medizin.uni-tuebingen.de/de/das-klinikum/mitarbeiter/profil/1965

... or reach him at: manfred.hallschmid@uni-tuebingen.de


Timestamps:

00:25: Introduction of our guest Manfred Hallschmid and his field of research

01:17: What is metabolism?

02:25: Which systems in the body and the brain are involved in food intake?

06:25: Top-down and bottom-up pathways linking metabolism with cognitive function, mental health, and mood

14:44: Key sex differences in metabolism and their onset

21:03: Influence of sex hormones on metabolism

27:10: How do the hormonal fluctuations across the female life span impact metabolism?

42:42: Summary

45:00: Future directions in research

48:05: Take home message

49:55: Closing remarks


Outline & questions: Nina Goll & Franziska Weinmar

Sound recording: Nina Goll with the equipment of the IRTG2804

Editing: Franziska Weinmar


Do you have any feedback, suggestions, or questions? Get in touch with us: irtg2804.podcast@gmail.com

Are you intrigued by this topic and want to be kept updated? Follow us on twitter: @irtg2804 or instagram: @irtg2804


Hosted on Acast. See acast.com/privacy for more information.

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3 months ago
51 minutes 1 second

Let's Talk About Women
Let's Talk About the (Stalled) Gender Revolution

Welcome Prof. Dr. Pia Schober, who brings us a sociological perspective on our field of research!

Pia is a professor at the University of Tübingen, where she leads the Chair of Microsociology in the Department of Sociology and is also part of our IRTG 2804. As an expert on gender-specific and social inequalities focusing on the impact of childcare and education policies, Pia talks about historic and current trends of the gender revolution in this podcast. Why does the gender revolution seem to be stalling? Is there a "paradox in women's well-being" - and how could we explain it?


Listen to explore a different perspective and gather food for thought to start a discussion in your circles too! 


If you would like to get in touch with Pia, you can find her here: https://uni-tuebingen.de/fakultaeten/wirtschafts-und-sozialwissenschaftliche-fakultaet/faecher/fachbereich-sozialwissenschaften/soziologie/institut/personen/prof-pia-s-schober/

... or reach her at: pia.schober@uni-tuebingen.de


Timestamps:

00:25: Introduction of our Guest Pia Schober and her field of research

01:47: How is gender defined in sociology?

02:50: What kind of social inequalities are related to gender and how has this changed over time?

08:14: Factors, phases and current trends of the gender revolution

17:00: Benefits of the gender revolution

23:44: The longitudinal female well-being paradox

36:33: Summary

39:00: How can we move towards a less polarized discussion around gender, while acknowledging the effect that gender has on mental health & well-being?

47:01: What methods does Pia Schober use in her research?

49:21: Closing remarks


Outline & questions: Hanna Wierenga & Franziska Weinmar

Sound recording: Franziska Weinmar with the equipment of the IRTG2804

Editing: Franziska Weinmar


Do you have any feedback, suggestions, or questions? Get in touch with us: irtg2804.podcast@gmail.com

Are you intrigued by this topic and want to be kept updated? Follow us on twitter: @irtg2804 or instagram: @irtg2804


Hosted on Acast. See acast.com/privacy for more information.

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4 months ago
50 minutes 46 seconds

Let's Talk About Women
Let's Talk With Young Researchers: Zoé Bürger

Let's Talk WITH Young Researchers: our podcast sideline in which we give the word to young researchers in the field of women's mental health!


In this episode, meet Zoé Bürger, PhD researcher in the Women's Mental Health and Brain Function lab in Tübingen, where she has been working with Prof. Birgit Derntl.


We talk about Zoé's research on hormonal contraception, specifically the hormonal IUD, and stress. Besides, Zoé shares her PhD journey over the past years, how she faced challenges, and found her "village". In the end of the podcast, Zoé answers our famous quick "3 Burning Questions":

  • Who is your science crush? 
  • What did you not know/expect before starting a PhD? 
  • What do you enjoy most about your work as a PhD researcher? 


Do you want to get in touch with Zoé? Reach out to: Zoe.Buerger@med.uni-tuebingen.de

... or find her on Linkedin: https://www.linkedin.com/in/zoebuerger/


Sound recording: Franziska Weinmar

Editing: Franziska Weinmar


Do you have any feedback, suggestions, or questions? Get in touch with us: irtg2804.podcast@gmail.com

Are you intrigued by this topic and want to be kept updated? Follow us on twitter: @irtg2804 or instagram: @irtg2804


Hosted on Acast. See acast.com/privacy for more information.

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6 months ago
53 minutes 54 seconds

Let's Talk About Women
Let's Talk About Endometriosis

March is Endometriosis Awareness Month - so Let's Talk About Endometriosis!


In this conversation, Elle Murata, PhD researcher in the Cognitive Neuroendocrinology Lab at the University of California, is sharing insights into neuroscience research on endometriosis.

What is endometriosis? Why is it important to consider endometriosis in neuroscience research? How are Elle and her research group exploring the topic? Elle is here to answer all these questions! 

In addition, she talks about the challenges of this research, her experiences as a young researcher and what she envisions for the future field.


Visit the Cognitive Neuroendocrinology Jacob's Lab website here: https://jacobs.psych.ucsb.edu/

If you would like to get in touch with Elle, you can find her here: https://jacobs.psych.ucsb.edu/people/elle-murata

... or reach her at: elle.murata@psych.ucsb.edu


Timestamps:

00:26 Introduction of our guest Elle Murata and her field of research

01:48 What is endometriosis?

08:17 Why is it important to investigate endometriosis from a neuroscientific point of view?

14:15 Elle's neuroscience research project on endometriosis

24:39 Aims & hypotheses of the project

26:29 Possible implications

32:35 Challenges of this research topic

35:58 Summary

38:55 Closing remarks & future directions in research

39:50 Elle's experience as a young researcher


Outline & questions: Franziska Weinmar

Sound recording: Franziska Weinmar with the equipment of the IRTG2804

Editing: Franziska Weinmar


Do you have any feedback, suggestions, or questions? Get in touch with us: irtg2804.podcast@gmail.com

Are you intrigued by this topic and want to be kept updated? Follow us on twitter: @irtg2804 or instagram: @irtg2804



Hosted on Acast. See acast.com/privacy for more information.

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7 months ago
43 minutes 59 seconds

Let's Talk About Women
Let's Talk About Cognition During Hormonal Fluctuations

How do hormonal fluctuations during the menstrual cycle or when using oral contraceptives ("the pill") affect cognitive functions?


In this episode, Franziska speaks with Prof. DDr. MMMag. Belinda Pletzer (Paris-Lodron University of Salzburg), a leading expert in cognitive neuroscience and neuropsychology, especially when it comes to hormone-brain interactions. With a diverse background spanning biology, psychology, philosophy, and mathematics, Belinda's research focuses particularly on the effects of sex hormones and gender-related aspects of neuroscience, such as the effects of hormonal contraceptives on the female brain.


Together we explore if and how cognitive performance and brain activity are affected by the menstrual cycle, premenstural syndrome (PMS), and oral contraceptives. Belinda also shares her hypothesis on hormonal sensitivity across the female lifespan and whether more or actually less sensitivity could be a risk factor for mental health. As always, we conclude with an outlook on how our guest envisions the future development of the research field. 


Join us for a deep dive into this enlightening conversation - and find out if the myth that all women are affected by the menstrual cycle holds true...


Visit the website of Belinda's research group: https://ccns.plus.ac.at/labs/sexandgender/

... and Belinda's profile: https://ccns.plus.ac.at/labs/sexandgender/members/belinda_pletzer/

If you would like to get in touch with Belinda, you can reach her at: Belinda.Pletzer@plus.ac.at


Timestamps:

00:27 Introduction of Belinda Pletzer and her field of research

02:20 The menstrual cycle and its phases

05:18 Oral contraceptives and their influence on the menstrual cycle

08:20 How do we define cognitive functions?

10:24 Investigating cognitive functions - Belinda's research

12:58 Does the menstrual cycle affect cognitive performance?

22:28 Belinda's research on PMS, mood and cognitive performance

33:08 Do oral contraceptives affect cognitive performance?

41:11 Hot Topic: Hormonal sensitivity - Belinda's hypothesis

46:30 Summary

49:54 Closing remarks and future directions in research 


Outline & questions: Franziska Weinmar

Sound recording: Franziska Weinmar with the equipment of the IRTG2804

Editing: Franziska Weinmar


Do you have any feedback, suggestions, or questions? Get in touch with us: irtg2804.podcast@gmail.com

Are you intrigued by this topic and want to be kept updated? Follow us on twitter: @irtg2804 or instagram: @irtg2804



Hosted on Acast. See acast.com/privacy for more information.

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8 months ago
52 minutes 20 seconds

Let's Talk About Women
Let's Talk About Premenstrual Dysphoric Disorder (PMDD)

Premenstrual dysphoric disorder (PMDD) approximately affects 2-5% of women around the world. In this episode we have Dr. Liza Kaltsouni, postdoc at Uppsala University, Department of Women's and Children's Health, as an expert in our podcast. During her PhD, Liza Kaltsouni conducted research on PMDD and collected various data, including brain data in the MRI scanner. This has influenced her holistic perspective on PMDD and the multimodal network approach needed to understand this multimodal disorder. In addition to pursuing such a multimodal approach for future research on PMDD, Liza emphasizes the importance of interdisciplinary work and the inclusion of the people for whom the research is intended. Following the motto “nothing good is easy”, Liza calls on us to listen more. And you can start today - by listening to this enlightening conversation!


Timestamps:

00:27 Introduction of our guest Dr. Liza Kaltsouni & her field of research

01:46 What is premenstrual dysphoric disorder (PMDD) and how is it differed to premenstrual syndrome (PMS) ?

05:57 What do we know about underlying causes of PMDD?

12:13 Hormonal sensitivity hypothesis

18:22 What do we know about PMDD & brain structure + function?

27:57 Multimodal study project & findings of Liza Kaltsouni

37:55 Implications of Liza's research

41:10 Current available treatment for PMDD

44:59 Outlook: Upcoming treatment possibilities for PMDD?

48:50 Summary

52:27 Closing remarks & future directions in research 


Want to get in touch with Liza?

elisavet.kaltsouni@uu.se

https://www.uu.se/en/contact-and-organisation/staff?query=N19-2428


Sound recording: Franziska Weinmar at Recording Studio Blasenhus, Uppsala University 

Editing: Franziska Weinmar


Do you have any feedback, suggestions, or questions? Get in touch with us: irtg2804.podcast@gmail.com

Are you intrigued by this topic and want to be kept updated? Follow us on twitter: @irtg2804 or instagram: @irtg2804



Hosted on Acast. See acast.com/privacy for more information.

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9 months ago
59 minutes 42 seconds

Let's Talk About Women
Let's Talk With Young Researchers: Hanna Wierenga

Let's Talk WITH Young Researchers: our podcast sideline in which we give the word to young researchers in the field of women's mental health!


In this episode, meet Hanna Wierenga, PhD Candidate in the IRTG2804, who is working with Prof. Pia Schober (Tübingen) and Prof. Alkistis Skalkidou (Uppsala) on gender identity and ideologies and mental health, specifically during and after pregnancy.


We talk about Hanna's PhD projects and journey so far, how she deals with setbacks and that a PhD is like detective work. In the end of the podcast, Hanna answers our quick "3 Burning Questions":

  • Who is your science crush? 
  • What did you not know/expect before starting a PhD? 
  • What do you enjoy most about your work as a PhD researcher? 


Do you want to get in touch with Hanna Wierenga? Reach out to: hanna.wierenga@uu.se


Sound recording: Franziska Weinmar at Recording Studio Blasenhus, Uppsala University 

Editing: Franziska Weinmar


Do you have any feedback, suggestions, or questions? Get in touch with us: irtg2804.podcast@gmail.com

Are you intrigued by this topic and want to be kept updated? Follow us on twitter: @irtg2804 or instagram: @irtg2804



Hosted on Acast. See acast.com/privacy for more information.

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10 months ago
47 minutes 11 seconds

Let's Talk About Women
Let's Talk About Menopause

Despite being one of the major hormonal transition phases in the female lifespan, menopause is still underrepresented in medicine and research. Fortunately, this is changing - among others due to our guest, Dr. Claudia Barth, senior researcher at Diakonhjemmet Hospital and the Norwegian Centre for Mental Disorders Research in Oslo, who is an expert on female hormonal transitions and their effect on the brain and mental illness. In this episode Franziska sits down with Claudia to demystify menopause, asking about symptoms, mental health, and what we know about changes in the brain during the menopause transition. Also, they dive into why menopause has remained a blind spot in neuroscience so far and why this matters. With a glimpse into Claudia’s ERC grant on “Mapping Perimenopause", this episode offers a hopeful vision for future research on women’s health, where menopause is finally getting the attention it deserves.


Website to the ENIGMA consortium: https://enigma.ini.usc.edu/

Website to the ENIGMA Neuroendocrinology workgroup: https://enigma.ini.usc.edu/ongoing/enigma-neuroendocrinology/

Website to the ENIGMA Early Onset Psychosis workgroup: https://enigma.ini.usc.edu/ongoing/enigma-eop-working-group/

If you would like to get in touch with Claudia, you can reach her at: claudia.barth@medisin.uio.no

... or find her work at: https://www.researchgate.net/profile/Claudia-Barth


Timestamps:

00:27: Introducing Dr. Claudia Barth and her field of research

02:17: How do we define menopause?

05:38: What happens during menopause?

11:40: Menopause and the brain

17:35: Vulnerabilities and associated diseases

21:32: Why do we know so little? Menopause and research

31:55: Menopause and mental health

43:22: Outlook: Claudia's ERC Project on "Mapping Perimenopause"

50:56: Summary

54:06: Closing remarks and future directions in research 


Outline & questions: Franziska Weinmar

Sound recording: Franziska Weinmar with the equipment of the IRTG2804

Editing: Franziska Weinmar


Do you have any feedback, suggestions, or questions? Get in touch with us: irtg2804.podcast@gmail.com

Are you intrigued by this topic and want to be kept updated? Follow us on twitter: @irtg2804 or instagram: @irtg2804



Hosted on Acast. See acast.com/privacy for more information.

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11 months ago
57 minutes 51 seconds

Let's Talk About Women
Let's Talk About Adolescents & Social Media

After our summer break we're back to talk about women! In this episode we dive into the period of adolescence with Dr. Jolien Trekels, who is currently a postdoctoral researcher at the University of North Carolina. Jolien unpacks how the adolescent brain and body develop during this critical period and explains the complex effects of social media on well-being, from the negative to the positive. Through a bio-psycho-social lens, Jolien and Franziska discuss state-of-the-art insights into mental health and gender differences on how today’s youths interact with social media. We end this episode as always with a look ahead and Jolien's thoughts on the future directions in this research field.


Timestamps:

00:27 Introduction of Dr. Jolien Trekels

02:12 About adolescence: How is this period characterized?

03:32 Changes in the brain and the body

08:50 What is (social) media?

11:09 Negative effects of social media on well-being

15:09 The "Swiss cheese model"

17:09 Positive effects and negative effects of social media in adolescence

29:07 Sex/gender differences in social media use patterns and mental health

37:38 Influence of hormones on adolescent girls regarding their social media use

39:45 Summary

42:30 Closing remarks & future directions in research


Outline & questions: Edita Karavidaj & Franziska Weinmar

Sound recording: Franziska Weinmar with the equipment of the IRTG2804

Editing: Franziska Weinmar


Do you have any feedback, suggestions, or questions? Get in touch with us: irtg2804.podcast@gmail.com

Are you intrigued by this topic and want to be kept updated? Follow us on twitter: @irtg2804 or instagram: @irtg2804



Hosted on Acast. See acast.com/privacy for more information.

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1 year ago
48 minutes 46 seconds

Let's Talk About Women
Let's Talk With Young Researchers: Gloria Matte Bon

Let's Talk WITH Young Researchers: our new podcast sideline in which we give the word to young researchers in the field of women's mental health!


We kick-off with our very own Gloria Matte Bon, PhD Candidate in the IRTG2804, who is working with Prof. Tobias Kaufmann, applying computational models to investigate sex differences in brain structure, with particular focus on hormonal transition periods and women’s mental health.


We end this podcast by introducing a new closing category and Gloria is the first one to answer our "3 Burning Questions":

  • Who is your science crush? 
  • What did you not know/expect before starting a PhD? 
  • What do you enjoy most about your work as a PhD researcher? 


Gloria's hot-off-the-press-paper: Modeling brain sex in the limbic system as phenotype for female-prevalent mental disorders (Matte Bon, Kraft, Comasco, Derntl, & Kaufmann, 2024). https://bsd.biomedcentral.com/articles/10.1186/s13293-024-00615-1


Sound recording: Franziska Weinmar with the equipment of the IRTG2804

Editing: Franziska Weinmar


Do you have any feedback, suggestions, or questions? Get in touch with us: irtg2804.podcast@gmail.com

Are you intrigued by this topic and want to be kept updated? Follow us on twitter: @irtg2804 or instagram: @irtg2804



Hosted on Acast. See acast.com/privacy for more information.

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1 year ago
42 minutes 15 seconds

Let's Talk About Women
Let's Talk About Computational Methods in Women’s Health

Computational methods and machine learning are currently THE hot-topics and they are also applied in neuroscience research, showing us where the field is heading in the future. If you have ever wondered how these methods work, what their advantages - but also limitations - are and how they are implemented in research on women's mental health: We got you!


In this episode Franziska is hosting Tobias Kaufmann, professor of neurotechnology and computational psychiatry at the University of Tübingen, who is also part of the IRTG2804. Tobias explains the basics of computational methods and gives us concrete examples of his own work, providing a first glimpse into the computational world. Also, we hear about his new ERC project: "HealthyMom: Modeling and maintaining maternal mental health".


Timestamps:

00:25 Introduction

01:18 Computational psychiatry: Advantages & limitations

10:15 Tobias' computational methods & examples: Prediction & classification models

21:14 Computational methods in women's (mental) health: Focus on adolescence

30:11 HealthyMom Project: Brain plasticity during pregnancy loss

40:26 Recruitment information for Healthy Mom Study

41:30 Summary

43:40 Next steps in computational psychiatry and women's mental health


Website to Kaufmann Lab: https://www.kaufmannlab.org/

About the HealthyMom Project: https://www.kaufmannlab.org/post/20230202-erc-consolidator-grant/


References:

  • Population-based neuroimaging reveals traces of childbirth in the maternal brain (de Lange, Kaufmann et al., 2019). https://doi.org/10.1073/pnas.1910666116
  • Menarche, pubertal timing and the brain: female-specific patterns of brain maturation beyond age-related development (Gottschwesky, Kraft, & Kaufmann, 2024). https://bsd.biomedcentral.com/articles/10.1186/s13293-024-00604-4
  • Domain adapted brain network fusion captures variance related to pubertal brain development and mental health (Kraft, Alnaes, & Kaufmann, 2023). https://www.nature.com/articles/s41467-023-41839-w
  • Modeling brain sex in the limbic system as phenotype for female-prevalent mental disorders (Matte Bon, Kraft, Comasco, Derntl, & Kaufmann, 2024). https://bsd.biomedcentral.com/articles/10.1186/s13293-024-00615-1


Outline & questions: Franziska Weinmar & Gloria Matte Bon

Sound recording: Franziska Weinmar with the equipment of the IRTG2804

Editing: Franziska Weinmar


Do you have any feedback, suggestions, or questions? Get in touch with us: irtg2804.podcast@gmail.com

Are you intrigued by this topic and want to be kept updated? Follow us on twitter: @irtg2804 or instagram: @irtg2804



Hosted on Acast. See acast.com/privacy for more information.

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1 year ago
48 minutes 4 seconds

Let's Talk About Women
Let's Talk About Brain SHAPERs

Celebrate with us the first anniversary episode of Let's Talk About Women!! - This time as PhD Candidate Franziska is hosting Dr. Nicole Petersen, Assistant Professor at the Department of Psychiatry and Biobehavioral Sciences, UCLA, California. Directing the Translational Neuroimaging Lab, Nicole's research focuses on neuromodulation and neuroendocrinology. Amongst others, she has investigated the effects of the menstrual cycle and oral contraceptives on brain and behavior.


In this episode, Nicole explains what "SHAPERs" are and what we know about their effects on the brain - but also what gaps there are still today. As one of the founding chairs of the ENIGMA Consortium for Neuroendocrinology, Nicole introduces the idea of ENIGMA and the working group and explains how this can contribute to rigorous studies, which will allow us to address exactly these knowledge gaps. 


Timestamps:

02:00 - Introduction of our guest Dr. Nicole Petersen and her field of research

02:30 - Explaining underlying concepts: What are hormones?

04:22 - Do sex hormones have functions beyond reproduction?

05:44 - The acronym SHAPERs & how it emphasizes on the dual role of sex hormones

08:38 - How are sex hormones associated with specific psychological aspects?

10:29 - Example: The influence of sensitivity to sex hormones on emotions

12:26 - Mysteries in neuroscience: How exactly are psychological conditions related to sex hormones?

14:18 - Why are some women more sensitive to hormones & mental health disorders?

17:20 - What does research say about the effects of SHAPERs on the brain?

23:20 - Is it especially important to investigate SHAPERs in women?

26:44 - The ENIGMA Neuroendocrinology consortium: aims & how to join!

34:26 - Summary

36:20 – Future directions in research & next steps for investigating women’s mental health

41:09 – Closing remarks


Website to the ENIGMA consortium: https://enigma.ini.usc.edu/

Website to the ENIGMA Neuroendocrinology workgroup: https://enigma.ini.usc.edu/ongoing/enigma-neuroendocrinology/

If you would like to get in touch with Nicole, you can reach her at: npetersen@ucla.edu

... or find her research group here: https://www.translational-neuroimaging.com/home


Sound recording: Franziska Weinmar with the equipment of the IRTG2804

Editing: Franziska Weinmar


Do you have any feedback, suggestions, or questions? Get in touch with us: irtg2804.podcast@gmail.com

Are you intrigued by this topic and want to be kept updated? Follow us on twitter: @irtg2804 or instagram: @irtg2804



Hosted on Acast. See acast.com/privacy for more information.

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1 year ago
42 minutes 25 seconds

Let's Talk About Women
Let's Talk About Hormonal Sensitivity

Welcome to this episode with Vibe Froekjaer, Professor in Neuropsychiatry at the Department of Clinical Medicine, Copenhagen University, Denmark.

Join us as Vibe and Franziska delve into the question of why some women are more vulnerable to mental health problems during hormonal transitions, unraveling state of the art research on the hypothesis of “hormonal sensitivity”. From discussing the latest findings on genetic and neural mechanisms to the potential of psychoeducation, this episode promises an insightful conversation and valuable takeaways. Discover how understanding hormonal sensitivity can empower women to navigate their mental health journeys more effectively and hear Vibe sharing her vision on the final question: “What is the next question to solve regarding hormonal sensitivity across the female lifespan – and how could we do so?”


Timestamps:

00:02:10 - The "3 P's" across the female lifespan: puberty, pregnancy & perimenopause

00:08:02 - Incidence of mental health problems across the female lifespan: windows of vulnerability?

00:09:14 - Why are some women more prone to suffer from hormone-related mental health problems?

00:16:57 - Hormonal-related depressive symptoms and the role of serotonin

00:19:26 - Hormone variability and gene expression

00:26:12 - Large-scale changes in the brain in response to induced hormone variability

00:29:02 - Hormonal manipulation effects on reward responses

00:33:41 - Is hormonal sensitivity a phenomenon that translates across the lifespan?

00:42:03 - What epidemiological data from Denmark tell us about risks for depressive symptoms across transition years

00:44:00 - Can we identify women who are hormone sensitive?

00:47:41 - What could be preventive and treatment approaches for women identified as hormone-sensitive before hormonal transition phases?

00:52:56 - How the concept of hormonal sensitivity can reduce stigma involved in depressive symptoms and empower women

00:56:03 - Summary

00:58:41 - What is the next question to solve regarding hormonal sensitivity across the female lifespan – and how could we do so?

01:03:50 - Closing remarks


Sound recording: Franziska Weinmar with the equipment of the IRTG2804

Editing: Franziska Weinmar


Do you have any feedback, suggestions, or questions? Get in touch with us: irtg2804.podcast@gmail.com

Are you intrigued by this topic and want to be kept updated? Follow us on twitter: @irtg2804 or instagram: @irtg2804



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1 year ago
1 hour 5 minutes 18 seconds

Let's Talk About Women
Let's Talk About Research on Hormonal Contraceptives

In this episode, PhD candidate Franziska Weinmar interviews Dr. Adriene Beltz, visiting Tübingen from the University of Michigan. The topic of today’s episode are hormonal intrauterine devices, short IUD. From contraceptives beyond the “pill” and hormonal contraceptive trends worldwide, they discuss how the IUD works, why it is important to look at potential effects of IUDs separately from oral contraceptives and what research there is on the IUD and mental health as well as the brain. Further, they discuss how a specific method of research, “intense longitudinal data”, can help understand individual variability within people to do better science and go towards individualized medicine. 


Timestamps:

01:30 Hormonal contraceptives beyond the “pill”

05:00 Trends in contraception worldwide / by age

06:45: How does the hormonal IUD work?

08:15: Hormonal levels in IUDs

10:30 Systemic IUD effects?

12:30 Combining OC and IUD in research?

15:00 IUDs in neuroscience research and types of progestins

23:10 IUD & the brain

25:50 Why is it so important to investigate hormonal contraceptives and IUDs specifically?

29:30: Summary

34:00 Outlook with focus on methods

37:30 Intense longitudinal data – what is it and why is it important

40:00 Paths to individualized medicine?

42:00 Diversity in research via intensive longitiudinal data

45:00 Summary and teaser for future episodes on stress & the IUD


Many thanks to Zoé Bürger for contributing to this episode!

Sound recording: Franziska Weinmar with the equipment of the IRTG2804

Editing: Franziska Weinmar


Do you have any feedback, suggestions, or questions? Get in touch with us: irtg2804.podcast@gmail.com

Are you intrigued by this topic and want to be kept updated? Follow us on twitter: @irtg2804 or instagram: @irtg2804



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1 year ago
49 minutes 5 seconds

Let's Talk About Women
Let's Talk About Hormonal Fluctuations Across the Female Lifespan

Welcome to a special episode, coming to you live and on-site from the Lorentz Center in Leiden, the Netherlands!

The Lorentz Center serves as a dynamic workshop hub, hosting international scientific meetings which bring together brilliant minds and foster an open and interactive atmosphere. 


In this episode, PhD Candidate Franziska Weinmar is taking you directly to the Lorentz workshop on "Hormonal fluctuations across the female lifespan". With 40 participants including researchers and clinicians from approximately 6 countries, this five-day intensive gathering in February 2024 promises lively exchanges, discussions, and reflections.

Join Franziska as she takes you through a series of 9 conversations, capturing the very fresh impressions and thoughts from different participants. Get ready to hear the pulse of the workshop, where ideas converge and minds collide – all in pursuit to move the field of research and clinical practice forward. And stay tuned for the announced outcomes! 


Speakers, in order of appearance:

00:01:38: Ellen de Bruijn, Professor, Leiden University

00:10:19: Birit Broekman, Medical Specialist, Amsterdam UMC

00:15:33: Anne Marieke Doornweerd, PhD Candidate, Utrecht University

00:27:25: Klara Sifalakis-Spalek, Postdoctoral Researcher, Amsterdam UMC

00:34:36: Alkistis Skalkidou, Professor, Uppsala University

00:40:12: Lotte Gerritsen, Associate Professor, Utrecht University

00:46:4: Hanna Wierenga, PhD Candidate, IRTG 2804, University of Tübingen

00:52:50: Claudia Barth, PhD, Diakonhjemmet Hospital Oslo

01:03:09: Birgit Derntl, Professor, IRTG 2804, University of Tübingen

01:12:10 Closing Remarks


Many thanks to the Lorentz Center for providing the space and opportunity for this workshop!

Sound recording: Franziska Weinmar with the equipment of the IRTG2804

Editing: Franziska Weinmar


Follow the FLAME (Female Lifespan Association for Mental Health and Neuroendocrinology) for future updates: https://www.linkedin.com/company/female-lifespan-research-initiative?trk=public_post-text


Do you have any feedback, suggestions, or questions? Get in touch with us: irtg2804.podcast@gmail.com

Are you intrigued by this topic and want to be kept updated? Follow us on twitter: @irtg2804 or instagram: @irtg2804



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1 year ago
1 hour 14 minutes 43 seconds

Let's Talk About Women
Let's Talk About the Parental Brain

Tune in to this episode for an enlightening conversation on the profound transformations of the brain in transition to mother- and parenthood: PhD candidate Franziska is interviewing Dr. Magdalena Martínez-García, researcher in the “Neuromaternal” group in Madrid. Using longitudinal neuroimaging studies, she and her team investigate structural and functional neuroplasticity across different stages of pregnancy and beyond. Don't miss out and join us when we dive into how (and why) both the maternal and paternal/parental brains are shaped by pregnancy, experience as well as time shared with the offspring.


Timestamps:

00:00 Introduction 

01:44 What happens during pregnancy within the mother's body?

04:00 What is neuroplasticity?

06:05 Neuroplasticity during pregnancy

18:18 Do pregnancy-related changes in the brain reverse?

23:35 Why does the brain of mothers-to-be change?

27:20 Why we should NOT be scared of pregnancy-related neuroplasticity and brain volume shrinkage!

32:02 What are neural plasticity mechanisms during pregnancy in human mothers?

37:01 Research on brains of fathers and parents

42:03 Time spent with the child matters: experience-induced plasticity

43:46 What is the importance of research on the parental brain?

47:20 Summary 

50:25 The next step in research on neuroplasticity of peripartum and parenthood


Many thanks to Julia Siódmiak for contributing to this episode!

Sound recording: Franziska Weinmar with the equipment of the IRTG2804

Editing: Franziska Weinmar


Do you have any feedback, suggestions, or questions? Get in touch with us: irtg2804.podcast@gmail.com

Are you intrigued by this topic and want to be kept updated? Follow us on twitter: @irtg2804 or instagram: @irtg2804



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1 year ago
57 minutes 52 seconds

Let's Talk About Women
Let's Talk About Stress & Stress Regulation

With our first episode in 2024, we are back and ready to talk about stress and stress regulation! In this episode PhD candidate Franziska Weinmar hosts Dr. Lydia Kogler, a clinical psychologist by training, expert on the neuroscience of stress and associate of the IRTG2804. Together they dive into the complex world of stress and stress regulation - especially if and how women and men differ in this regard. To this end, this episode leaves us with more insights, a suggestion on how to improve our resilience to stress, and curiosity for future talks on this topic!


Stress is part of our everyday life. But what does stress mean and how does the body react to stress? In this episode Lydia explains:

01:21: What is stress? (01:21)

05:30: How does the stress response leads to behavioural and endocrine adaptations?

08:28: The role of cortisol

11:49: How do we induce stress in the lab?

14:22: What neurological changes come with stress?

15:34: How chronic stress affects the body...

18:58: ... and mental health

Next, Lydia talks about sex/gender differences:

22:58: Sex differences in the stress response...

26:25: ... its neural basis....

27:17: ... and psychological effects

28:00 Sex differences in stress related disorders

30:18: Reasons behind sex differences

33:50: Consequences of sex differences in stress response

35:15: Why is it important to look into sex differences?

39:24: Mechanisms of stress regulation

44:49: How self-esteem influences the stress response

49:00: Sex differences on a neuronal level...

50:03: ... and a hormonal level

50:18: Implications of coping mechanisms

52:00: Summary

54:57: What is the next question to ask about sex/gender differences in stress response or regulation, especially considering female-specific processes? 


Many thanks to Anna Denninger for contributing to this episode!

Sound recording: Franziska Weinmar with the equipment of the IRTG2804

Editing: Franziska Weinmar


Do you have any feedback, suggestions, or questions? Get in touch with us: irtg2804.podcast@gmail.com

Are you intrigued by this topic and want to be kept updated? Follow us on twitter: @irtg2804 or instagram: @irtg2804



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1 year ago
58 minutes 55 seconds

Let's Talk About Women
Let's Talk About the Power of Natural Rhythms

In this episode, we're hosting cognitive neuroscientist Prof. Sara Mednick who is visiting Tübingen all the way from the University of California, Irvine. Being an expert in biorhythms, she explains the importance of natural up- and downstates such as related to sleep, the menstrual cycle and the transition to menopause. What are biorythms and how can we use especially downstates to improve our wellbeing? How can we use the knowledge on hormonal changes to balance our mood and cognition? Sara is here to give us a new perspective on our natural rhythms!


Timestamps:

01:30 What are biorythms?

03:31: What is the power of downstates?

06:42: How can we use biorythms & downstates for our wellbeing & cognition?

08:00: Sleep as restorative downstate

12:40: What is the menstrual cycle?

14:32: How does the menstrual cycle affect other biorythms?

15:50: Sleep as mood buffer during the menstural cylce

21:40: A change in prespective on the menstrual cylce

30:40: Changes in sleep in the transition to menopause

34:22: Subjective vs. objective measures of sleep & cognition

39:45: Wellbeing during (the transition) to menopause

42:53: Summary

44:40: A future vision for women's mental health: awareness, reseach & empowerement.


Sara's popular-scientific books: https://www.saramednick.com/books

  • "The Power of the Downstate: Recharge Your Life Using Your Body's Own Restorative Systems" (2022)
  • "Take a Nap! Change Your Life. The Scientific Plan to Make You Smarter, Healthier, More Productive" (2006)


Thanks to Nina Röhm for supporting & exchanging ideas in preparation of this episode!

Sound recording: Nina Röhm with the equipment of the IRTG2804

Editing: Franziska Weinmar


Do you have any feedback, suggestions, or questions? Get in touch with us: irtg2804.podcast@gmail.com

Are you intrigued by this topic and want to be kept updated? Follow us on twitter: @irtg2804 or instagram: @irtg2804



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1 year ago
49 minutes 47 seconds

Let's Talk About Women
Let's Talk About Psycho-Neuro-Immunology in Pregnancy

In this episode we talk about one of the major transition periods many women will undergo throughout their life: pregnancy. How does the field of psych-neuro-immunology help us to understand pregnancy and related mental health problems?  


From Uppsala in Sweden, PhD Candidate Franziska Weinmar is interviewing Dr. Emma Fransson, a child psychologist and associate professor at Uppsala University and at the Karolinska Institute in Sweden. 

Emma’s research focuses on mental and reproductive health, specifically in identifying biomarkers for pregnancy-related complications. These include mental health problems such as postpartum depression, which is affecting up to one in five women after giving birth.  


Dive with us into the interactions of the immune system, the brain, and psychological wellbeing, as we outline what is happening during pregnancy, what makes some women vulnerable for depression associated to pregnancy, and how we can use this information in the future. 


Timestamps:

01:30 What happens during pregnancy? 

05:10 What is “psycho-neuro-immunology”?

07:35 Pregnancy as a psycho-neuro-immunological transition phase 

09:05 What factors contribute to postpartum depression? 

11:55 Major depression and postpartum depression: Differences and subtypes? 

14:50 Inflammatory markers during pregnancy: Risk for postpartum depression?

18:15 Predictive markers for postpartum depression? 

20:40 Screening and prediction of depressive symptoms across the postpartum period 

25:45 Preventive approaches of postpartum depression: Using psycho-neuro-immunology.

29:18 What do we know about the pregnant brain? 

33:24 How does postpartum depression affect the child?     

36:36 Summary

38:33 What is the next big step for research in psychoneuroimmunology during pregnancy, especially when considering pregnancy-related mental health? 


Thanks to Hanna Wierenga for exchanging ideas in preparation of this episode!

Sound recording: Recording Studio Blasenhus, Uppsala University 

Editing: Franziska Weinmar with support from Andreas Forsberg (Recording Studio Blasenhus, Uppsala University) 


Do you have any feedback, suggestions, or questions? Get in touch with us: irtg2804.podcast@gmail.com

Are you intrigued by this topic and want to be kept updated? Follow us on twitter: @irtg2804 or instagram: @irtg2804



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2 years ago
41 minutes 36 seconds

Let's Talk About Women

“Let’s Talk About Women” is a podcast initiative of the International Research Training Group (IRTG) 2804 (Tübingen x Uppsala), which investigates women's mental health across the reproductive lifespan.

Here we share insights from interdisciplinary research on women's mental health by talking to experts in fields of neuroscience, psychology, biology, and medicine. Beyond that, we will shed light on ongoing doctoral projects among our PhD candidates to get a glimpse into state-of-the-art and hot-topic research.

This podcast is not only for fellow researchers inside and outside the area of women's mental health, but also for people interested in science and curious about this topic!


Do you have any feedback, suggestions, or questions? Get in touch with us: irtg2804.podcast@gmail.com

Are you intrigued by this topic and want to be kept updated? Follow us on twitter: @irtg2804 or instagram: @irtg2804


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