In this episode of Zebra Talks, host Dr. Libby Hinsley welcomes Dr. Jessica Eccles, a prominent consultant psychiatrist and researcher, to discuss her personal and professional experiences with hypermobility syndromes. Dr. Eccles shares insights from her extensive research on the links between hypermobility, anxiety, neurodevelopmental conditions, and chronic health issues such as fibromyalgia and ME/CFS. She explains how differences in brain structure and function, along with abnormal autonomic nervous system responses, can affect those with hypermobility. Dr. Eccles also introduces a novel treatment approach, the ADAPT therapy, designed to reduce anxiety in hypermobile individuals. The conversation highlights the importance of proper diagnosis, medical education, and innovative therapeutic strategies for managing these complex conditions. 00:00 Introduction to Zebra Talks 00:35 Meet Dr. Jessica Echols 01:34 Dr. Echols' Personal Journey with Hypermobility 04:00 Discovering the Link Between Hypermobility and Anxiety 08:50 Exploring Brain Differences in Hypermobile Individuals 11:00 The Role of the Involuntary Nervous System 17:02 Novel Treatments and Future Research 21:05 Connections Between Hypermobility and Neurodivergence 35:45 Challenges and Future Directions in Medical Education 39:53 Conclusion and Final Thoughts