Beta blocker overdose is one of the most dangerous cardiovascular emergencies, leading to bradycardia, hypotension, seizures, and cardiogenic shock. Agents like propranolol, metoprolol, carvedilol, and atenolol can cause life-threatening toxicity, especially with ER formulations or co-ingestions. 📚 MINI COURSES, STUDY GUIDES, PRACTICE QUESTIONS, AD FREE VIDEOS, EDUCATIONAL DISCUSSIONS in our WBM Emergency Critical Care Patreon Community - Join Today!! https://www.patreon.com/c/WhiteBoardMedicine In this podcast, we cover: What beta blockers are and why overdoses are so dangerous 💊 Mechanisms of toxicity: β1/β2 blockade, sodium channel blockade, lipophilicity, and QT prolongation 🔬 Clinical presentation: bradycardia, shock, seizures, bronchospasm, hypoglycemia 🩺 Emergency management: airway/IV access, glucagon, HIET (high-dose insulin therapy), vasopressors, sodium bicarbonate, lipid emulsion, ECMO 🚑 Diagnostic workup and monitoring strategies in the ED/ICU Prognosis, pearls, and practice questions for learners Link To Video Version:https://www.youtube.com/watch?v=Y2zwZl323j0 DISCLAIMER THIS PODCAST DOES NOT PROVIDE MEDICAL ADVICE. The information, including but not limited to, audio, text, graphics, images and other material contained on this website are for informational purposes only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read, watched, or listened to on this video, or any other videos, reports, texts tweets or other sources.