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This podcast seeks to help family physicians and other clinicians incorporate the best available evidence into their everyday clinical decision making.
#4 Probiotics for the Prevention of Antibiotic-Associated Diarrhea
What's the Proof?
35 minutes
3 years ago
#4 Probiotics for the Prevention of Antibiotic-Associated Diarrhea
In this episode, the What's the Proof team is shocked by the practice-changing evidence surrounding the use of probiotics in preventing antibiotic-associated diarrhea.
Also, in "Residents Ask the Darnedest Things," Dr. Caviness shares what she learned when a medical student asked about co-testing for influenza along with COVID-19 in symptomatic patients.
Most Studied Probiotics:
In adults: Saccharomyces boulardii, Lactobacillus acidophilus, Lactobacillus casei
* Dose: 10 to 50 billion CFUs per day
In children: Lactobacillus rhamnosus, Saccharomyces boulardii
* "High-dose": >5 billion CFUs per day
Episode Outline:
* Intro/background 02:00
* Evidence for use in adults 08:20
* Potential harms 15:29
* Which probiotics are recommended? 16:29
* Evidence for use in children 20:08
* "Residents Ask The Darnedest Things" 28:09
Links from this episode:
* 2017 Cochrane review "Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children" https://pubmed.ncbi.nlm.nih.gov/29257353/
* 2010 RCT on use of probiotics for AAD and CDAD in hospitalized adults https://pubmed.ncbi.nlm.nih.gov/29257353/
* 2019 Cochrane Review "Probiotics for the prevention of pediatric antibiotic-associated diarrhea" https://pubmed.ncbi.nlm.nih.gov/31039287/
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Credits:
* Hosts: Bobby Scott, MD, FAAFP; Sandy Robertson, PharmD; Dawn Caviness, MD, BSN
* Production & Cover Art: Bobby Scott, MD, FAAFP
* Music: Twisterium, MondayHopes, Muzaproduction, and SergeQuadrado from Pixabay
What's the Proof?
This podcast seeks to help family physicians and other clinicians incorporate the best available evidence into their everyday clinical decision making.
