Newcastle disease is largely under control in the United States, yet vaccination choices still shape flock health and performance. In this episode, host Andy Vance talks with Dr. Brian Jordan of Zoetis about why not all Newcastle vaccines behave the same inside the bird and how a data-first approach can reveal hidden gaps in protection.   Dr. Jordan explains the concept of vaccine take, how routine PCR monitoring shows whether birds actually received and replicated a live vaccine, and why low take rates can set up a rolling reaction that chips away at growth, feed conversion, and overall flock immunity. He compares popular live strains and clarifies where recombinant options fit, then walks through a simple plan for spot-checking hatchery applications, reading CT distributions, and deciding whether the problem is process or product. The conversation closes with questions veterinarians should ask suppliers, how to layer Newcastle programs with other respiratory vaccines, and why quarterly monitoring can keep protocols honest without adding constant lab costs.   CREDITS Host - Andy VanceProducer - Lyndsey JohnsonAudio Editor & Engineer - Michael Lunt   LEGAL The information provided in this episode of Unplucked is for informational and educational purposes only and should not be considered professional advice. While we discuss scientific research, public health, and industry practices, this podcast does not substitute for advice from qualified industry and scientific professionals. The views expressed in this episode are solely those of the host and guests and do not necessarily reflect the official opinions of The Poultry Science Association, their respective affiliates, or employees.