How do social and cultural changes occur, and how can policy be influenced to encourage these changes, particularly in terms of aiding people who are marginalized and stigmatized in our society? The award-winning research team from the University of Limerick's Centre for Social Issues Research is collaborating with government and advocacy groups to help those who are directly affected by disability, those who care for those who are disabled, child carers, and those who are affected by domestic violence The centre has a long history of working together to address the issues that underprivileged members of our community face. During the Covid-19 pandemic, the Centre for Social Issues Research recommended governments in Ireland and the United Kingdom on how to effectively help COVID-19 front-line workers, carers, and those with underlying health concerns, as well as how to encourage people to follow public health recommendations. Prof Orla Muldoon, Prof Mike Quayle, Dr Sarah Jay, Dr Stephen Gallagher and Dr Siobhan Howard join our host Prof Helena Lenihan to discuss their award-winning collaborations.