Brian Armstrong is the co-founder and CEO of Coinbase, a leading cryptocurrency company that provides exchange, brokerage, and custody services to 100M+ verified users in over 100 countries. Founded in 2012, Coinbase went public in 2021 on the NASDAQ under the ticker COIN and as of August 2025 has a market cap of $83 billion. Brian is also the co-founder of New Limit, a longevity biotech company on a mission to significantly extend human lifespan that recently raised a $130M Series B led by Kleiner Perkins and angels including John and Patrick Collison, Elad Gil, and Joshua Kushner, among others. We covered: Working with the government When to jump to the hot new thing Choosing what frontiers to prioritize The inner game of being contrarian --- Timestamps: (0:00) Intro (0:26) Becoming the everything chain (4:20) Story behind the GENIUS Act (5:33) Working with regulators (10:45) The future of crypto and the government (17:10) When to jump to the hot new thing (23:03) Choosing what frontiers to prioritize (29:59) Brain-computer interface tech (34:48) Inside the mind of a contrarian (43:52) Creating a sustainable lifestyle --- More on Brian: https://www.coinbase.com/ https://www.newlimit.com/ https://x.com/brian_armstrong More on Jack: https://www.altcap.com/ https://x.com/jaltma --- https://linktr.ee/uncappedpod Email: friends@uncappedpod.com