Manny is joined by co-host Denali Rose and MSKCC’s Joe Lengfellner, to discuss the shifting focus from a one-size-fits-all approach to redefine site centricity. They talk about how the role of a clinical trial coordinator is changing, the challenges of managing data and protocol amendments across different systems, and the promise of technologies like EHR-to-EDC to streamline workflows. They debate the potential of LLMs to revolutionize patient recruitment and widen access to clinical trials, addressing the critical issue of reaching more diverse patient populations.