From our first breath, the air we breathe and our genes shape how our lungs function. It’s a complex interplay we began exploring in our season four episode “Take A Deep Breath: Treating Asthma.” Today, we’re branching out to discuss lung biology and the diseases that make it difficult to breathe. In this episode, co-host Maria Wilson speaks with Dorothy Cheung, Executive Group Medical Director, and Daniel Lafkas, Senior Principal Scientist, Translational Discovery Research, Roche, to understand how conditions with unmet need like chronic bronchitis and emphysema disrupt lung function. They discuss the challenges to treating lung diseases and explore promising approaches, from cutting-edge imaging technologies that help researchers uncover early drivers of disease, to treatments aimed at stopping the loss of lung function and restoring it.
Read the full text transcript at www.gene.com/stories/decoding-lung-disease
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From our first breath, the air we breathe and our genes shape how our lungs function. It’s a complex interplay we began exploring in our season four episode “Take A Deep Breath: Treating Asthma.” Today, we’re branching out to discuss lung biology and the diseases that make it difficult to breathe. In this episode, co-host Maria Wilson speaks with Dorothy Cheung, Executive Group Medical Director, and Daniel Lafkas, Senior Principal Scientist, Translational Discovery Research, Roche, to understand how conditions with unmet need like chronic bronchitis and emphysema disrupt lung function. They discuss the challenges to treating lung diseases and explore promising approaches, from cutting-edge imaging technologies that help researchers uncover early drivers of disease, to treatments aimed at stopping the loss of lung function and restoring it.
Read the full text transcript at www.gene.com/stories/decoding-lung-disease
S5E01: Merging Minds and Machines: The Future of Drug Discovery
Two Scientists Walk Into a Bar
36 minutes 50 seconds
1 year ago
S5E01: Merging Minds and Machines: The Future of Drug Discovery
Computational approaches have revolutionized how we interpret data. With the advent of genomic sequencing, scientists can derive significant conclusions from sequence data. For example, through transcriptomics – the study of genes and their expression in different cells – researchers have made groundbreaking discoveries in fields like developmental and disease biology. More recently, computational approaches have expanded with the introduction of generative artificial intelligence (AI) and its ability to generate new insights from massive datasets, diverse in scope, which can be validated in the lab. In this episode, co-host Maria Wilson sits down with John Marioni, Senior Vice President and Head of Computational Sciences, to discuss how computational methods can complement other research techniques to expedite drug discovery, enhance clinical trials, and prevent biases, ensuring the development of medicines that can treat people of diverse backgrounds.
Read the full text transcript at www.gene.com/stories/merging-minds-and-machines-the-future-of-drug-discovery
Two Scientists Walk Into a Bar
From our first breath, the air we breathe and our genes shape how our lungs function. It’s a complex interplay we began exploring in our season four episode “Take A Deep Breath: Treating Asthma.” Today, we’re branching out to discuss lung biology and the diseases that make it difficult to breathe. In this episode, co-host Maria Wilson speaks with Dorothy Cheung, Executive Group Medical Director, and Daniel Lafkas, Senior Principal Scientist, Translational Discovery Research, Roche, to understand how conditions with unmet need like chronic bronchitis and emphysema disrupt lung function. They discuss the challenges to treating lung diseases and explore promising approaches, from cutting-edge imaging technologies that help researchers uncover early drivers of disease, to treatments aimed at stopping the loss of lung function and restoring it.
Read the full text transcript at www.gene.com/stories/decoding-lung-disease