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Trenches in Transplant Surgery
Sabin Subedi
45 episodes
1 week ago
Step into the forefront of abdominal transplant surgery — where innovation meets ongoing complexity. Machine perfusion and normothermic regional perfusion (NRP) are reshaping organ preservation and donor utilization, with growing evidence that these technologies improve graft assessment and early outcomes. Yet reviews continue to highlight key challenges — ischemia–reperfusion injury, biliary complications in DCD grafts, and the logistical demands of perfusion platforms. Despite these hurdles, transplantation is shifting from an urgent, unpredictable field toward a planned, daytime specialty. The next horizon, underscored by recent expert reviews, is true organ banking — bringing us closer to on-demand, schedulable transplantation.
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Medicine
Health & Fitness
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All content for Trenches in Transplant Surgery is the property of Sabin Subedi and is served directly from their servers with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.
Step into the forefront of abdominal transplant surgery — where innovation meets ongoing complexity. Machine perfusion and normothermic regional perfusion (NRP) are reshaping organ preservation and donor utilization, with growing evidence that these technologies improve graft assessment and early outcomes. Yet reviews continue to highlight key challenges — ischemia–reperfusion injury, biliary complications in DCD grafts, and the logistical demands of perfusion platforms. Despite these hurdles, transplantation is shifting from an urgent, unpredictable field toward a planned, daytime specialty. The next horizon, underscored by recent expert reviews, is true organ banking — bringing us closer to on-demand, schedulable transplantation.
Show more...
Medicine
Health & Fitness
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DCD vs DBD — Inside the Critical Step of Organ Procurement
Trenches in Transplant Surgery
42 minutes 8 seconds
1 month ago
DCD vs DBD — Inside the Critical Step of Organ Procurement

Following a recent New York Times report that questioned the ethics and safety of donation after circulatory death (DCD), this episode clarifies how DCD and donation after brain death (DBD) actually work in U.S. organ procurement. We explain why DCD now accounts for ~43% of deceased donors (≈7,300 in 2024, 13,496 transplants) and how it complements the ~9,700 brain-dead donors who still provide most organs. We explore the surgical, ethical, and logistical safeguards that make procurement safe and trustworthy, the innovations (machine perfusion, NRP) that expand DCD use, and why expert procurement is the critical bridge that preserves organ quality, upholds public trust, and makes every transplant possible.

Trenches in Transplant Surgery
Step into the forefront of abdominal transplant surgery — where innovation meets ongoing complexity. Machine perfusion and normothermic regional perfusion (NRP) are reshaping organ preservation and donor utilization, with growing evidence that these technologies improve graft assessment and early outcomes. Yet reviews continue to highlight key challenges — ischemia–reperfusion injury, biliary complications in DCD grafts, and the logistical demands of perfusion platforms. Despite these hurdles, transplantation is shifting from an urgent, unpredictable field toward a planned, daytime specialty. The next horizon, underscored by recent expert reviews, is true organ banking — bringing us closer to on-demand, schedulable transplantation.