#15 Francesca del Bufalo: CAR-T cells for neuroblastoma

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Trainee Pearls

The EBMT Trainee Committee

16 episodes

2 days ago

Welcome to “Trainee Pearls”, a new initiative brought to you by the EBMT Trainee Committee to deliver the most important messages (“the pearls”) of high-profile research works in hematology and bone marrow transplant to our fellow trainees all over the world. The topics will span from classical hematology to more focused bone marrow transplant research. The selected research article will be discussed directly with young authors who have been involved with the published work.

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All content for Trainee Pearls is the property of The EBMT Trainee Committee and is served directly from their servers with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.

Medicine

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#15 Francesca del Bufalo: CAR-T cells for neuroblastoma

Trainee Pearls

23 minutes 54 seconds

2 years ago

#15 Francesca del Bufalo: CAR-T cells for neuroblastoma

Immunotherapy with chimeric antigen receptor (CAR)–expressing T cells that target the disialoganglioside GD2 expressed on tumor cells may be a therapeutic option for patients with high-risk neuroblastoma. In an academic, phase 1–2 clinical trial, the investigators enrolled patients (1 to 25 years of age) with relapsed or refractory, high-risk neuroblastoma in order to test autologous, third-generation GD2-CAR T cells expressing the inducible caspase 9 suicide gene (GD2-CART01). https://www.nejm.org/doi/full/10.1056/NEJMoa2210859 ALSO AS VIDEO ON YOUTUBE

https://youtu.be/o1DVDcrrHFA

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