Dr. WaiFung Tsang is a Clinical Psychologist specializing in addiction, neurodevelopmental disorders, trauma, and the therapeutic use of psychedelics within traditional settings. Based at the Maudsley Hospital, King’s College London, he has been actively involved in research exploring the potential of ayahuasca—a traditional Amazonian psychedelic brew—in treating mental health conditions. On this episode of the Trailmark Podcast, Dr. Tsang discusses the fascinating intersection of science and tradition in psychedelic research, delving into topics such as the epigenetic and neurological effects of ayahuasca, the importance of set and setting, and the integration of indigenous wisdom in modern studies. He also explores how preparation and integration shape psychedelic experiences, the role of gut microbiomes, and the broader cultural and spiritual impacts of these substances on individuals and society.