Forget everything you ever read in a textbook when it comes to antimicrobial resistance (AMR) and sepsis complications – because they rarely play by the rules. They evolve, adapt, and strike before it’s too late. While classic symptoms like fever, tachycardia, and hypotension are well known, the real challenge lies in recognizing the unexpected to reduce your mental list of those unknown, unknowns.
Hosted by Critical Care RN & CNS Author Nicole Kupchik, The Sepsis Spectrum is an exploration of real-world patient cases, expert insights, and clinical deep dives to unravel the most complex presentations facing modern medicine. Through gripping stories and in-depth interviews, Nicole examines diagnostic challenges, cutting-edge treatments, and the growing threat of AMR.
Designed for healthcare professionals at every level, The Sepsis Spectrum is about leaving you with more than compelling stories—it’s a vital resource in podcast form. Whether you’re at the bedside or in the classroom, you’ll finish each episode with practical, life-saving knowledge—and earn free CE Contact Hours for Nurses along the way.
The fight against sepsis and AMR starts with recognition — because the most dangerous threats are the ones you don’t see coming.
A Sepsis Alliance Podcast
Nursing CE Contact Hours Available - Sepsis Alliance is a provider approved by the California Board of Registered Nursing, Provider Number CEP17068. Most U.S. states accept CE provided through the California Board of Registered Nursing, but nurses in other states should check with their local and state accrediting bodies to confirm. Canadian and non-US based nurses should consult their provincial or territorial regulator to confirm acceptance.
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Forget everything you ever read in a textbook when it comes to antimicrobial resistance (AMR) and sepsis complications – because they rarely play by the rules. They evolve, adapt, and strike before it’s too late. While classic symptoms like fever, tachycardia, and hypotension are well known, the real challenge lies in recognizing the unexpected to reduce your mental list of those unknown, unknowns.
Hosted by Critical Care RN & CNS Author Nicole Kupchik, The Sepsis Spectrum is an exploration of real-world patient cases, expert insights, and clinical deep dives to unravel the most complex presentations facing modern medicine. Through gripping stories and in-depth interviews, Nicole examines diagnostic challenges, cutting-edge treatments, and the growing threat of AMR.
Designed for healthcare professionals at every level, The Sepsis Spectrum is about leaving you with more than compelling stories—it’s a vital resource in podcast form. Whether you’re at the bedside or in the classroom, you’ll finish each episode with practical, life-saving knowledge—and earn free CE Contact Hours for Nurses along the way.
The fight against sepsis and AMR starts with recognition — because the most dangerous threats are the ones you don’t see coming.
A Sepsis Alliance Podcast
Nursing CE Contact Hours Available - Sepsis Alliance is a provider approved by the California Board of Registered Nursing, Provider Number CEP17068. Most U.S. states accept CE provided through the California Board of Registered Nursing, but nurses in other states should check with their local and state accrediting bodies to confirm. Canadian and non-US based nurses should consult their provincial or territorial regulator to confirm acceptance.
Can standard sepsis protocols catch what the gut already knows? In this conversation, Nicole sits down with Dr. Laura Kahn to explore how the microbiome could transform our understanding of sepsis, antimicrobial resistance, and upstream prevention. They dive into One Health thinking, gut-brain signaling, dysbiosis as an early disease marker, and why your patient’s toilet might someday replace lab work. A provocative look at the limits of protocolized medicine and the potential power of microbial diagnostics.
Featured Guest:
Laura Kahn, MD, MPH, MPP (LinkedIn @https://www.linkedin.com/in/laura-kahn-79b01510/): Physician and researcher at Princeton University focused on clinical judgment, public policy, and One Health systems.
Key Takeaways:
Understand the One Health model and why it's crucial for addressing modern health threats across humans, animals, and ecosystems.
Explore how antimicrobial resistance (AMR) develops and spreads from livestock practices to poor sanitation and why the microbiome plays a central role.
Learn how human-pet relationships, dietary patterns, and environmental exposures all shape microbial health and, potentially, susceptibility to infection.
See how gut dysbiosis may serve as an early indicator of systemic dysfunction, possibly even preceding conditions like sepsis.
Discover emerging ideas for integrating microbiome monitoring into clinical care, including the future of diagnostic toilets and personalized microbial assessments.
Walk away with actionable insights for strengthening antimicrobial stewardship, counseling patients more holistically, and considering interspecies health in everyday practice.
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Get in Touch: info@sepsis.org
Or Visit Us At: SepsisPodcast.org
Connect with Nicole on Socials: @nicolekupchik
Connect with Sepsis Alliance on Socials: @sepsisalliance
To Learn More About Sepsis, Visit EndSuperbugs.org
Produced by: Human Content and Sepsis Alliance
The Sepsis Spectrum
Forget everything you ever read in a textbook when it comes to antimicrobial resistance (AMR) and sepsis complications – because they rarely play by the rules. They evolve, adapt, and strike before it’s too late. While classic symptoms like fever, tachycardia, and hypotension are well known, the real challenge lies in recognizing the unexpected to reduce your mental list of those unknown, unknowns.
Hosted by Critical Care RN & CNS Author Nicole Kupchik, The Sepsis Spectrum is an exploration of real-world patient cases, expert insights, and clinical deep dives to unravel the most complex presentations facing modern medicine. Through gripping stories and in-depth interviews, Nicole examines diagnostic challenges, cutting-edge treatments, and the growing threat of AMR.
Designed for healthcare professionals at every level, The Sepsis Spectrum is about leaving you with more than compelling stories—it’s a vital resource in podcast form. Whether you’re at the bedside or in the classroom, you’ll finish each episode with practical, life-saving knowledge—and earn free CE Contact Hours for Nurses along the way.
The fight against sepsis and AMR starts with recognition — because the most dangerous threats are the ones you don’t see coming.
A Sepsis Alliance Podcast
Nursing CE Contact Hours Available - Sepsis Alliance is a provider approved by the California Board of Registered Nursing, Provider Number CEP17068. Most U.S. states accept CE provided through the California Board of Registered Nursing, but nurses in other states should check with their local and state accrediting bodies to confirm. Canadian and non-US based nurses should consult their provincial or territorial regulator to confirm acceptance.