Small chemical groups inserted or removed from around DNA may affect gene expression and so be a way to control genetic blood disorders such as sickle cell anaemia and beta thalassemia. 

Is the US shooting itself in the foot, or shooting itself in the head? As Donald Trump removes funding for medical research, climate research and more, Matthew England reflects on how science will help us cope with a changing world.

A 100-yr flood is now a more regular occurrence in the German town of Passau, bringing widespread destruction, another local impact of a planet getting hotter.

There was a famous debate. And truly weird ideas about how the universe works at a subatomic level. Shelby Traynor traces the history of quantum mechanics.

Discover the story of a pair of brothers who invented an early electric scooter, humidicrib, fax machine, Olympic scoreboard — and much more! — in their South Australian workshop from the 1930s to the 60s. We also learn about a trial that's generated energy from the waves, and unearth two rare photographs of a long-lost bandicoot species.

In an electrifying episode of the Science Show, find out how getting struck by a bolt from the heavens can help at least one species of tall tree not only survive, but thrive.  Then step back in time to solve a tool-making mystery in Samoa and discover hidden treasures in centuries-old books — including a bubonic plague flea.

We hear from scientists who push the boundaries of creation, whether that's building wild and wacky snack flavours (successfully) or cloning extinct tropical frogs (unsuccessfully … so far).  And since President Donald Trump retook office, the state of health and science research in the US has been precarious for many who work in those areas.  But there is a silver lining. Other countries such as Australia are implementing programs to recruit US researchers looking to relocate.

Karl Popper (1902-1994) is regarded as one of the greatest philosophers of science of the twentieth century. Alan Saunders presented this portrait of Karl Popper for The Science Show in January 2001.

The overland telegraph connecting Australia to the world was completed just over 150 years ago. It was built due to the dedication of a public servant, Charles Todd.

Roger Short (1930_2021) discusses influences in his early life, and some of his research achievements including melatonin as a controller of circannual rhythms, and aspects of reproductive biology across the animal world.

Get ready for gravitons, dark photons and transition states. Kathryn Zurek takes us on a tour of the bewildering world of quantum physics.

People have been in the Australian wilderness for generations. But can people be considered part of the natural landscape or will they always have an impact?

She could only read and write from age 10. She reared children and had a first unsupportive husband. But Mary Somerville was able to correct the work of Isaac Newton, help discover Neptune, and write a science book which became a university text.

Amateur fossil hunters make a major discovery. And Marilyn Renfree describes the sophisticated reproduction of marsupials.

David Walker at UCLA says he can halt aging in fruit flies. Can the same concepts be applied to humans? And three tertiary students describe their combination of science and artistic pursuits.

Mansi Kasliwal describes how she detects supernovae – the massive stellar explosions where elements are formed. We learn how dung beetles saved the Australian environment from the big problem, and David Attenborough shares his love for Birds-of-paradise.

Sharks have survived 500 million years while mass extinctions have wiped out other species. Now, sharks are under threat.

Palaeontology helps reveal why some animals are in desperate need of help while others thrive.

A protein in the immune system, DECTIN-1 - primarily responsible for defending the body against fungal infections, has been found to control the severity of autoimmune diseases such as irritable bowel disease (IBS), type 1 diabetes, eczema, and other chronic disorders.

Soils are too often neglected but caring for them brings many benefits for plant nutrition, human health and a boost for the farm economy.