The Rounds Table

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The Rounds Table

Dr. John Fralick and Dr. Michael Fralick

387 episodes

4 days ago

Send us a text Welcome back Rounds Table Listeners! We are back today with a Classic Rapid Fire episode. This week, Drs. Mike and John Fralick discuss two recent papers: the effects of perioperative hypotension-avoidance versus hypertension-avoidance strategies on delirium and 1-year cognitive decline after noncardiac surgery, and the effect of as-needed albuterol–budesonide on risk of severe asthma exacerbation among patients with moderate-to-severe asthma. Two papers, here we go! Effects of...

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Health & Fitness,

All content for The Rounds Table is the property of Dr. John Fralick and Dr. Michael Fralick and is served directly from their servers with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.

Send us a text Welcome back Rounds Table Listeners! We are back today with a Classic Rapid Fire episode. This week, Drs. Mike and John Fralick discuss two recent papers: the effects of perioperative hypotension-avoidance versus hypertension-avoidance strategies on delirium and 1-year cognitive decline after noncardiac surgery, and the effect of as-needed albuterol–budesonide on risk of severe asthma exacerbation among patients with moderate-to-severe asthma. Two papers, here we go! Effects of...

Show more...

Health & Fitness,

Episodes (20/387)

The Rounds Table

Episode 130 - Hypotension-Avoidance vs Hypertension-Avoidance and Albuterol–Budesonide in Mild Asthma

Send us a text Welcome back Rounds Table Listeners! We are back today with a Classic Rapid Fire episode. This week, Drs. Mike and John Fralick discuss two recent papers: the effects of perioperative hypotension-avoidance versus hypertension-avoidance strategies on delirium and 1-year cognitive decline after noncardiac surgery, and the effect of as-needed albuterol–budesonide on risk of severe asthma exacerbation among patients with moderate-to-severe asthma. Two papers, here we go! Effects of...

4 days ago

23 minutes

The Rounds Table

Episode 129 - Antihypertensive Medication Timing

Send us a text Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. John Fralick. This week, he discusses a recently published trial examining the effect of bedtime vs morning administration of antihypertensive medications on major cardiovascular events and death. Here we go! Antihypertensive Medication Timing and Cardiovascular Events and Death: The BedMed Randomized Clinical Trial (0:00 – 5:18).The Good Stuff: Resources for trainees (5:19 - 6:20):Medicine Pods...

1 week ago

6 minutes

The Rounds Table

TBT - The Top 5 Papers of 2024

Send us a text Welcome back Rounds Table Listeners! In this throwback episode, Drs. Mike and John Fralick chat about five important research studies published in 2024: Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction (FINEARTS-HF) (0:00 – 4:09)Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity (SURMOUNT-OSA) (4:10 – 9:28)Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes (FLOW) (9:29 – 14:23)Tirzepatide for Metabol...

2 weeks ago

25 minutes

The Rounds Table

Episode 128 - Finerenone with SGLT2 inhibitors for CKD and Type 2 Diabetes

Send us a text Welcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the simultaneous initiation of SGLT2 inhibitors and finerenone (a nonsteroidal mineralocorticoid receptor antagonist) in persons with chronic kidney disease and type 2 diabetes. Here we go! Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes (0:00 – 9:28).Calling keen trainees! (9:29 - 10:28) Trainees, med ...

3 weeks ago

10 minutes

The Rounds Table

Episode 127 - Leukocytoclastic Vasculitis with Karim Ladak

Send us a text Welcome back Rounds Table Listeners! We are back this week with a special podcast episode. Dr. Mike Fralick sits down with Dr. Karim Ladak—rheumatologist and internist, Clinical Assistant Professor at McMaster University, and host of the Rheumatology for the Royal College podcast—to talk about leukocytoclastic vasculitis. Here we go! Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

1 month ago

22 minutes

The Rounds Table

Episode 126 - Sotatercept for Pulmonary Arterial Hypertension

Send us a text Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. John Fralick. This week, he discusses a recently published trial exploring the effects of add-on sotatercept in patients with advanced pulmonary arterial hypertension and a high risk of death. Here we go! Sotatercept in Patients with Pulmonary Arterial Hypertension at High Risk for Death (0:00 – 5:38).The Good Stuff: 2025 Scripps National Spelling Bee winning word: éclaircissement (5:39 - 6:34)Q...

1 month ago

6 minutes

The Rounds Table

Episode 125 - Top Papers from the 2025 American Diabetes Association (ADA) Session

Send us a text Welcome back Rounds Table Listeners! We are back today with a special Rapid Fire Podcast. This week, Dr. Mike Fralick and guest host Danielle Cutler discuss the top papers from the 2025 American Diabetes Association (ADA) Scientific Session. Hot off the presses, here we go! Once-Monthly Maridebart Cafraglutide for the Treatment of Obesity — A Phase 2 Trial (0:00 - 6:05)Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist, in Early Type 2 Diabetes (6:06 - 13:22)Stem Cell–...

1 month ago

21 minutes

The Rounds Table

Episode 124 - 2024 KDIGO Clinical Practice Guidelines for Chronic Kidney Disease

Send us a text Welcome back Rounds Table Listeners! Today we have the next episode in our Clinical Practice Guidelines series. Drs. Mike and John Fralick discuss the top takeaways from the 2024 KDIGO Clinical Practice Guidelines for chronic kidney disease. Here we go! 1. KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease (0:00 - 24:24) Access the KDIGO 2024 "Top 10 Takeaways" PDFs here: https://kdigo.org/guidelines/ckd-evaluation-and-manage...

1 month ago

25 minutes

The Rounds Table

Episode 123 - Trial Files Top 5 RCTs

Send us a text Welcome back Rounds Table Listeners! Today we have another special episode— Trial Files turns two years old this June, and we're celebrating with an episode summarizing the Top 5 RCTs in the Trial Files catalogue to date. Dr. Mike Fralick takes us through five trials in 15 minutes. Here we go! 1. Effects of Semaglutide on Chronic Kidney Disease in Patients with Type 2 Diabetes (0:00 - 3:08) 2. Restrictive or Liberal Transfusion Strategy in Myocardial Infarction and Anemia (3:09...

2 months ago

14 minutes

The Rounds Table

Episode 122 - Opioids vs. Non-Opioids for Chronic Pain, IV Albumin for SBP, and PPI for GI Bleed

Send us a text Welcome back Rounds Table Listeners! Today we're introducing a new format—the first episode in our Trial Files series, where we provide an overview of a recent Trial Files issue. This week, Dr. Mike Fralick discusses three trials included in a recent throwback issue: opioids versus non-opioids for chronic pain; IV albumin for renal impairment and mortality; and omeprazole before endoscopy in patients with GI bleed. Three trials, 9 minutes, here we go! 1. Effect of Opioid vs Non...

2 months ago

8 minutes

The Rounds Table

Episode 121 - Tirzepatide vs. Semaglutide for Obesity

Send us a text Welcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recently published head-to-head trial exploring the safety and efficacy of tirzepatide compared to semaglutide for obesity management. Here we go! Tirzepatide as Compared with Semaglutide for the Treatment of Obesity (0:00 – 7:07).The Good Stuff: Trial Files, a free monthly newsletter on practice-changing trials, delivered straight to your inbox. (7:08 - 7:53)Quest...

2 months ago

7 minutes

The Rounds Table

Episode 120 - Top 5 Drug Interactions You Are Missing with David Juurlink

Send us a text Welcome back Rounds Table Listeners! We are back this week with a special podcast episode. Dr. Mike Fralick sits down with Dr. David Juurlink, pharmacologist and internist, Professor of Medicine at the University of Toronto, and head of the Clinical Pharmacology and Toxicology division at Sunnybrook Health Sciences Centre, to chat about the top drug interactions you might be missing. Here we go! Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtW...

2 months ago

25 minutes

The Rounds Table

Episode 119 - Semaglutide for MASH

Send us a text Welcome back, Rounds Table Listeners! This week we have a solo episode with Dr. John Fralick, discussing a recently published trial of the GLP-1 receptor agonist semaglutide for the treatment of metabolic dysfunction–associated steatohepatitis (MASH). Here we go! Phase 3 Trial of Semaglutide in Metabolic Dysfunction–Associated Steatohepatitis (0:00 – 6:33).The Good Stuff: Go Leafs go!Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @Medicine...

2 months ago

6 minutes

The Rounds Table

Episode 118 - Lorundrostat for Uncontrolled Hypertension

Send us a text Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the safety and efficacy of lorundrostat (an aldosterone synthase inhibitor) in treatment of uncontrolled and treatment-resistant hypertension. Here we go! Lorundrostat Efficacy and Safety in Patients with Uncontrolled Hypertension (0:00 – 7:02).The Good Stuff: Trial Files, a free monthly newsletter on practice-changing tr...

3 months ago

7 minutes

The Rounds Table

Episode 117 - Brensocatib for Bronchiectasis and Alteplase for Posterior Circulation Ischemic Stroke

Send us a text Welcome back Rounds Table Listeners! We are back today with our Classic Rapid Fire Podcast. This week, Dr. Mike Fralick and special guest Dr. Laiya Carayannopoulos from the Intern at Work Podcast and our Medicine Pods collaboration discuss two recent papers: the use of brensocatib (a DPP-1 inhibitor) to treat bronchiectasis, and the effect of alteplase administered 4.5 to 24 hours after stroke in patients with mild posterior circulation stroke who did not receive thrombectomy. ...

3 months ago

26 minutes

The Rounds Table

Episode 116 - 2025 ACC/AHA Clinical Practice Guidelines for Acute Coronary Syndrome

Send us a text Welcome back Rounds Table Listeners! Today we're introducing a new format—the first episode in our Clinical Practice Guidelines series. This week, Drs. Mike and John Fralick discuss the 2025 ACC/AHA Clinical Practice Guidelines for Acute Coronary Syndrome. Here we go! 2025 ACC/AHA/ACEP/NAEMSP/SCAI Guideline for the Management of Patients With Acute Coronary Syndromes (0:00 - 18:56)Mike's interview with Dr. Jeff Carson: Episode 110 - Restrictive versus Liberal Transfusion in Myo...

3 months ago

20 minutes

The Rounds Table

Episode 115 - Tirzepatide for Obesity Treatment and Diabetes Prevention

Send us a text Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the role of tirzepatide in weight reduction and diabetes prevention in persons with obesity. Here we go! Tirzepatide for Obesity Treatment and Diabetes Prevention (0:00 – 10:24).The Good Stuff: We've launched qMonthly, a monthly blog highlighting headliners and hidden gem trials published each month. Check it out here!&nb...

3 months ago

11 minutes

The Rounds Table

Episode 114 - Liberal Fluid Intake versus Fluid Restriction in Chronic Heart Failure

Send us a text Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. John Fralick. This week, he discusses a recently published trial examining liberal fluid intake vs. fluid restriction in chronic heart failure. Here we go! Liberal fluid intake versus fluid restriction in chronic heart failure: a randomized clinical trial (0:00 – 4:20).And for the Good Stuff: starpowerdrummer on YouTube (4:21 – 5:20).Questions? Comments? Feedback? We’d love to hear from you! @ro...

4 months ago

5 minutes

The Rounds Table

Episode 113 - Vitamin D in Clinically Isolated Syndrome Typical of Multiple Sclerosis

Send us a text Welcome back Rounds Table Listeners! We are back today with a solo episode with Dr. Mike Fralick. This week, he discusses a recently published trial exploring the role of high-dose Vitamin D therapy in reducing disease activity in patients with clinically isolated syndrome (CIS) typical of multiple sclerosis (MS). Here we go! High-Dose Vitamin D in Clinically Isolated Syndrome Typical of Multiple Sclerosis: The D-Lay MS Trial (0:00 – 7:35).Announcements (7:36 – 9:15): Canadian ...

4 months ago

9 minutes

The Rounds Table

Episode 112 - Top Papers from the 2025 American College of Cardiology (ACC) Session

Send us a text Welcome back Rounds Table Listeners! We are back today with a special Rapid Fire Podcast! This week, Drs. Mike and John Fralick discuss top papers from the 2025 American College of Cardiology (ACC) Annual Scientific Session. Hot off the presses, here we go! Extended Reduced-Dose Apixaban for Cancer-Associated Venous Thromboembolism (0:00 - 5:55)Dapagliflozin in Patients Undergoing Transcatheter Aortic-Valve Implantation (DapaTAVI) (5:56 - 9:51)Oral Semaglutide and Cardiov...

4 months ago

20 minutes