On today's episode, meet Mahesh Karande. Mahesh is President and CEO of Omega Therapeutics, a clinical stage biotechnology company in Cambridge, Mass. Mahesh is deeply experienced in running biopharma businesses across discovery, preclinical and clinical development, and commercialization.  Earlier, Mr. Karande spent several years at Novartis in senior leadership roles: VP and Head of US Oncology for solid tumors, President of Novartis Africa and President of Novartis Egypt. Mr. Karande has an M.B.A. from the Wharton School, University of Pennsylvania, an M.S. in engineering from Georgia Institute of Technology, and undergrad degree in engineering from the University of Bombay. Leading a company with an overarching ethos to be ambitious, yet humble.