An apple a day keeps the glucose away? Drs Oberg and Fraser discuss role of Phloretin, SGLT2/1i and GLUT in peritoneal membrane

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The #PDExchange Podcast

Peritoneal Dialysis International

16 episodes

6 days ago

Nephrologists and Peritoneal Dialysis enthusiasts Dr. Jeff Perl (Editor in Chief - PD International) and Dr. Nikhil Shah (Social Media Editor - PD International) co-host this podcast to discuss important research in #PeritonealDialysis from Peritoneal Dialysis International and other journals.

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An apple a day keeps the glucose away? Drs Oberg and Fraser discuss role of Phloretin, SGLT2/1i and GLUT in peritoneal membrane

The #PDExchange Podcast

31 minutes 56 seconds

2 years ago

An apple a day keeps the glucose away? Drs Oberg and Fraser discuss role of Phloretin, SGLT2/1i and GLUT in peritoneal membrane

Drs Oberg and Fraser along with Drs Perl and Shah discuss the exciting experiments regarding Phloretin (a GLUT blocker derived from apples!) and Phlorizin (a SGLT2 and SGLT1 blocker) and its potential use in Peritoneal Dialysis.

PDI paper link - Dual SGLT1/SGLT2 inhibitor phlorizin reduces glucose transport in experimental peritoneal dialysis - Giedre Martus, Karin Bergling, Carl M Öberg, 2022 (sagepub.com)

JASN paper link - Phloretin Improves Ultrafiltration and Reduces Glucose Absor... : Journal of the American Society of Nephrology (lww.com)

Questions of suggestions please reach out to Drs Nikhil Shah (https://twitter.com/dr_nikhilshah) and Jeff Perl (https://twitter.com/PD_Perls) via Twitter or write to nshah1@ualberta.ca