Video Episode: The New Chemist\'s Podcast- Understanding Cardiolipin\'s Function in Neurodegenerative Diseases

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The New Chemist's Podcast

Mr. David Joshua Ferguson, AMRSB AMRSC

135 episodes

3 weeks ago

The Podcast Series " The New Chemist"- where we discuss chemistry which simply put is the science of change, as well as careers, community, and research. We look forward to your subscriptions to support the work we are doing and follow us on Spotify and Apple Podcasts ! Note: The views on the podcast represent those of my guest and I. —- We encourage you to subscribe on Spotify and Apple Podcasts, to support our work!

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Video Episode: The New Chemist\'s Podcast- Understanding Cardiolipin\'s Function in Neurodegenerative Diseases - Thesis Abstract in ASL

The New Chemist's Podcast

2 minutes

2 years ago

Video Episode: The New Chemist\'s Podcast- Understanding Cardiolipin\'s Function in Neurodegenerative Diseases - Thesis Abstract in ASL

Episode Text:

Cardiolipin (CL), also known as diphosphatidyglycerol, is localized and synthesized exclusively in the mitochondria. This glycerophospholipid was first characterized by Mary Pangborn and McFarlane in 1941. Presently, CL is considered a potential therapeutic target for several neurodegenerative diseases (NDDs). Recent developments in the field of lipidomics indicate that the ratio of monolysocardiolipin-to-native CL is a valuable biomarker for diagnosing NDDs such as Barth Syndrome (BTHS). In this review, the role of lipidomics in understanding the function of CL in NDDs is reviewed.

Link: https://www.cambridge.org/engage/coe/article-details/645963ca1ca6101a450119f0