
In this episode, Bill Mann and Mark Connors sit down with Michael Nadeau, founder of The DeFi Report, to explore the future of digital assets, DeFi, and on-chain research. From macro backdrops to tokenization and the reflexivity of crypto markets, Michael shares how his journey from MIT and LinkedIn posts evolved into one of the most influential Substacks in digital assets.
The conversation spans:
Market updates and factor rotations in global assets
On-chain data vs. Wall Street narratives
The rise of stablecoins and Tether’s surprising role with U.S. treasuries
Why crypto’s reflexivity can be both powerful and dangerous
Web3’s shift from read/write to read/write/own
Institutional adoption, tokenization of real-world assets, and privacy in DeFi
The asymmetric bet on public blockchains
How frameworks from Kahneman’s Thinking, Fast and Slow help investors break fixed mindsets
Timestamps
00:45 – Market Setup & Fed Policy
Bill opens with inflation, interest rates, and global asset performance.
02:00 – Culture, Movies & Noise
Animal House quotes → how cultural distractions differ from on-chain truth.
07:30 – Jackson Hole: TradFi vs. Digital Assets
Digital asset symposium gains traction alongside the Fed’s annual gathering.
12:42 – The Origin of The DeFi Report
Michael’s journey from MIT → LinkedIn posts → Substack → Bankless partnership.
14:09 – The Asymmetric Bet
Why Bitcoin and public blockchains represented a career-changing investment thesis.
21:31 – Politics, Regulation & Gensler
Lessons from SEC leadership, courts, and the role of regulation in crypto adoption.
28:09 – Web3: Read. Write. Own.
How new data structures change ownership, content, and payments online.
34:28 – On-Chain Data & Reflexivity
Real-time transparency, resilience during FTX, and why crypto markets reprice instantly.
41:25 – DeFi Is Still Early
$900T of global assets vs. $7.5B tokenized today; institutions, KYC pools, and privacy.
49:39 – Stablecoins & The New Petrodollar
Tether’s U.S. Treasuries role, dollar network effects, and the geopolitics of stablecoins.
#DeFi #Crypto #OnChain #DefiReport #Stablecoins #Web3 #CryptoMarkets #NewBarbariansPodcast