Trials Beyond Borders: Clinical Trials in Latin America—Aligning Global Research with Local Realities In this episode, Dr. Carla Saenz, Regional Advisor for Bioethics at the Pan American Health Organization (PAHO), joins Willyanne DeCormier Plosky, Program Director at the MRCT Center, for a compelling conversation on the clinical trial landscape in Latin America. Together, they explore: How population demographics, different hospital systems, and insurance models influence trial participation and representation Ethical and regulatory pathways to increase inclusion in research The role of international guidance, including the CIOMS guidelines, in shaping ethical trial conduct Opportunities to design global trials that reflect and respect local contexts—without compromising scientific rigor This discussion underscores the importance of equitable access and locally relevant research in an increasingly global clinical trial ecosystem. For more about the MRCT Center’s work on Global Representation in Clinical Trials, click here or go to https://mrctcenter.org/representation-in-research/global_dei/.