In this episode, I sit down with Dr. Mary-Frances O’Connor, a clinical psychologist and neuroscientist, to explore the intricate relationship between grief, the brain, and the body. Drawing from her decades of research, Mary-Frances shares insights on how our bodies physically experience grief, why loss reshapes our inner world, and how cultural and personal differences shape the grieving process.Together, we discuss grief as a rite of passage, the impact of loss on identity, the role of guilt in bereavement—especially in cases of suicide—and the ways in which grief can manifest in unexpected physiological responses. We also examine the shifting cultural landscape of death and mourning, the importance of human connection in navigating loss, and how existential questions arise through grief.With both personal reflections and deep scientific insight, this conversation sheds light on the universal yet deeply individual nature of grief, offering a thoughtful exploration of what it means to carry loss within us.I sincerely hope you enjoy!