Madeleine Beth McCann (born 12 May 2003) disappeared on the evening of 3 May 2007 from her bed in a holiday apartment in Praia da Luz, a resort in the Algarve region of Portugal, sparking what one newspaper called "the most heavily reported missing-person case in modern history". Her whereabouts remain unknown.

Madeleine was on holiday from the UK with her parents, Kate and Gerry McCann; her two-year-old twin siblings; and a group of family friends and their children. She and the twins had been left asleep at 20:30​ in the ground-floor apartment, while the McCanns and friends dined in a restaurant 55 metres (180 ft) away. The parents checked on the children throughout the evening, until Madeleine's mother discovered she was missing at 22:00​. Over the following weeks, particularly after misinterpreting a British DNA analysis, the Portuguese police came to believe that Madeleine had died in an accident in the apartment and that her parents had covered it up. The McCanns were given arguido (suspect) status in September 2007, which was lifted when Portugal's attorney general archived the case in July 2008 because of a lack of evidence.

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