Dr. Patrick Hwu welcomes Dr. Elizabeth Jaffee of Johns Hopkins, a renowned leader in cancer immunotherapy. Dr. Jaffee shares the personal and scientific journey that led her to tackle one of oncology’s toughest challenges: pancreatic cancer. From her early fascination with virology to pioneering the use of genetically modified tumor vaccines, she has pushed the boundaries of what’s possible in cancer prevention and treatment. Dr. Jaffee also discusses efforts to use immunotherapy earlier — even preventively — and explores how AI and multi-modal data could revolutionize cancer risk prediction and early detection.