In this Gameweek 4 preview, we highlight the biggest matchups across European football following the international break. Can Bayern Leverkusen bounce back after their recent defeat? Manchester United face an early kickoff against Southampton, aiming to build momentum. Chelsea take on Bournemouth, while Arsenal and Tottenham prepare for a thrilling North London Derby. Over in Spain, Barcelona face Girona in a local derby, and Real Madrid look to recover from a disappointing draw. Get ready for all the key action and predictions for this exciting week of football!