Formerly a photographer and founder of The Center for Photography in Woodstock in 1977, Howard Greenberg has been one of a small group of gallerists, curators and historians responsible for the creation and development of the modern market for photography. Howard Greenberg Gallery—founded in 1981 and originally known as Photofind—was the first to consistently exhibit photojournalism and 'street' photography, now accepted as important components of photographic art.

Howard Greenberg Gallery maintains diverse and extensive holdings of photographic prints including Eugène Atget, Henri Cartier-Bresson, Bruce Davidson, André Kertész, William Klein, Gordon Parks, Edward Steichen, Paul Strand, Josef Sudek, and Edward Weston on its roster of artists. More recent additions include Edward Burtynsky, Jungjin Lee, Joel Meyerowitz, and Vivian Maier. In 2013 Howard Greenberg Gallery announced exclusive representation for the estates of Berenice Abbott and Arnold Newman. In 2018 Howard Greenberg Gallery became the primary representative of the Ray K. Metzker Archive.

In 2019 Greenberg sold 447 photographs from his collection to the Museum of Fine Art in Boston.

This conversation took place over Zoom in January 2023.