When it comes to the topic of drug discovery and development, scientists are busy furrowing their lab-goggled brows trying to understand what’s real and what’s hype when it comes to the power and potential of AI.
This *Resonance Test* conversation perfectly dramatizes the situation. In this episode, Emma Eng, VP of Global Data & AI, Development at Novo Nordisk, and scientist and strategist Chris Waller provide a candid view of drug development in the AI era.
“We're standing on a revolution,” says Eng, reminding us that “we've done it so many other times” with the birth of the computer and the birth of the internet. It’s prudent, she cautions, not to rush to judgement guided by either zealots or skeptics.
Waller says, of the articles about AI and leadership in *Harvard Business Review,* one could do “a search and replace ‘AI’ with any other technological change that's happened in the last 30 years. It's the same kind of trend and processes and characteristics that you need in your leadership to implement the technology appropriately to get the outcomes that you're looking for.”
Which means, for pharma, much uncertainty and much experimentation.
“I think experimentation is good,” says Eng, who then adds that we need to always keep track of what is it that we're experimenting on. She says that the word “experimentation” can “sound very fluid” but in fact, “It's a very structured process. You set up some very clear objectives and you either prove or don't prove those objectives.”
Waller references the various revolutions (throughput screening, combinational chemistry, data, and analytics revolutions) that pharma has seen and says: “We've all held out hope for each and every one of these revolutions that the drug discovery process is going to be shrunk by 50% and cost half as much. And every time we turn around, it's still 12 to 15 years, $1.5 to $2 billion.”
Will AI make the big difference, finally?
“Maybe we need to be revolutionized as an industry,” she says. “It can be hard to make much of a difference as long as there are few big players.” Just a few big players, she says, is “the nature of pharma.”
Of course, our scientists are measured in their assessments about industry change. After all, as Waller says, the systems involved—the human body, the regulatory environment, the commercial ecosystems—are all “super-complicated.”
Eng notes that an important side-effect around the AI hype is corporate interest in data. “Now it's much easier to put that topic on the table saying, ‘If you want to do AI, you need to take care of your data and you need to treat it like an asset.’”
Listen on as they test topics such as regional and regulatory challenges in AI adoption, change management, and future tech and long-term impact (watch out for quantum, everyone!).
In the end, Eng returns to the idea of revolutions. “You think you want so much change in the beginning which you don't get because it takes time,” says Eng. This makes us underestimate what will happen later. Having such a farseeing mindset is significant, she says, because “these technology shifts will have a large impact on the long term.”
Host: Alison Kotin
Engineer: Kyp Pilalas
Producer: Ken Gordon
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When it comes to the topic of drug discovery and development, scientists are busy furrowing their lab-goggled brows trying to understand what’s real and what’s hype when it comes to the power and potential of AI.
This *Resonance Test* conversation perfectly dramatizes the situation. In this episode, Emma Eng, VP of Global Data & AI, Development at Novo Nordisk, and scientist and strategist Chris Waller provide a candid view of drug development in the AI era.
“We're standing on a revolution,” says Eng, reminding us that “we've done it so many other times” with the birth of the computer and the birth of the internet. It’s prudent, she cautions, not to rush to judgement guided by either zealots or skeptics.
Waller says, of the articles about AI and leadership in *Harvard Business Review,* one could do “a search and replace ‘AI’ with any other technological change that's happened in the last 30 years. It's the same kind of trend and processes and characteristics that you need in your leadership to implement the technology appropriately to get the outcomes that you're looking for.”
Which means, for pharma, much uncertainty and much experimentation.
“I think experimentation is good,” says Eng, who then adds that we need to always keep track of what is it that we're experimenting on. She says that the word “experimentation” can “sound very fluid” but in fact, “It's a very structured process. You set up some very clear objectives and you either prove or don't prove those objectives.”
Waller references the various revolutions (throughput screening, combinational chemistry, data, and analytics revolutions) that pharma has seen and says: “We've all held out hope for each and every one of these revolutions that the drug discovery process is going to be shrunk by 50% and cost half as much. And every time we turn around, it's still 12 to 15 years, $1.5 to $2 billion.”
Will AI make the big difference, finally?
“Maybe we need to be revolutionized as an industry,” she says. “It can be hard to make much of a difference as long as there are few big players.” Just a few big players, she says, is “the nature of pharma.”
Of course, our scientists are measured in their assessments about industry change. After all, as Waller says, the systems involved—the human body, the regulatory environment, the commercial ecosystems—are all “super-complicated.”
Eng notes that an important side-effect around the AI hype is corporate interest in data. “Now it's much easier to put that topic on the table saying, ‘If you want to do AI, you need to take care of your data and you need to treat it like an asset.’”
Listen on as they test topics such as regional and regulatory challenges in AI adoption, change management, and future tech and long-term impact (watch out for quantum, everyone!).
In the end, Eng returns to the idea of revolutions. “You think you want so much change in the beginning which you don't get because it takes time,” says Eng. This makes us underestimate what will happen later. Having such a farseeing mindset is significant, she says, because “these technology shifts will have a large impact on the long term.”
Host: Alison Kotin
Engineer: Kyp Pilalas
Producer: Ken Gordon
The Resonance Test 99: Balazs Fejes and Boris Chave on Syz Bank's Digital Transformation
The EPAM Continuum Podcast Network
26 minutes 13 seconds
1 month ago
The Resonance Test 99: Balazs Fejes and Boris Chave on Syz Bank's Digital Transformation
“In French, we say when it’s raining at a wedding, it will be a beautiful marriage leading to a happy life,” says Syz Bank COO, Boris Chave. Reflecting on an announcement made on stage in 2023 alongside EPAM’s now-CEO Balazs Fejes during an afternoon storm in Geneva, Chave adds: “I think this rainy event was the beginning of a successful project and a happy partnership between Syz and EPAM.”
Swiss banks have a well-known reputation for being protective of customer data, and Syz Bank is no exception. For years, the bank relied on on-prem servers and top-shelf security solutions to protect its customer data. However, the cost of those solutions was rising sharply, which led Chave to wonder if there existed a better solution. “The challenge with our setup was that even though we had these best-in-breed technology solutions, the ongoing investments we needed to make to protect our data just weren’t sustainable. I had to ask myself, should we continue down this path with its huge impact on P&L? Not to mention I wasn’t comfortable with the complexity of our systems.”
Fast forward to June of 2025, and EPAM has just finished helping Syz Bank migrate all its IT infrastructure to cloud-based systems, no small feat. As Fejes points out, “You got new notebooks, new applications, you migrated everything to the cloud. You basically built, de facto, a brand-new bank.” As Chave notes, not only did EPAM help Syz Bank navigate the cloud migration, but we did so with minimal impact on operations. “So many aspects of this project have been a huge success. We delivered on time and on budget without any outages for customers or employees.”
The move to the cloud came at a rather fortuitous time. Fejes says: “When you and I met on that stage in 2023, nobody was really talking about AI yet. But now you’re probably finding yourself in a very privileged situation because some of your competitors might still need to work on what I would call the foundational elements of their infrastructure, whereas you’re in a situation where you can take advantage of the capabilities of the cloud.” Says Chave: “The foundation we have now will give us access to some of the best AI technology without having to make huge investments in infrastructure just to deliver something. We can try out new tools and pivot quickly.”
Beyond enabling new and surprising technologies, the move to the cloud also had another major impact on Syz Bank: a reduction in complexity. What was previously 140 applications working together to protect the bank’s data has been reduced to seven on the cloud system. “So many people are underestimating the impact of complexity in terms of environment stability and cost. Program simplification is probably one of the best ways to achieve cost-efficient operations,” says Fejes.
It might seem counterintuitive that such a complex transformation could result in such simplicity, but that’s exactly how this project played out. Now, with the stage set, let’s raise the curtain on this episode.
Host: Michael Nicholls
Engineer: Kyp Pilalas
Producer: Scott MacAllister
Executive Producer: Ken Gordon
The EPAM Continuum Podcast Network
When it comes to the topic of drug discovery and development, scientists are busy furrowing their lab-goggled brows trying to understand what’s real and what’s hype when it comes to the power and potential of AI.
This *Resonance Test* conversation perfectly dramatizes the situation. In this episode, Emma Eng, VP of Global Data & AI, Development at Novo Nordisk, and scientist and strategist Chris Waller provide a candid view of drug development in the AI era.
“We're standing on a revolution,” says Eng, reminding us that “we've done it so many other times” with the birth of the computer and the birth of the internet. It’s prudent, she cautions, not to rush to judgement guided by either zealots or skeptics.
Waller says, of the articles about AI and leadership in *Harvard Business Review,* one could do “a search and replace ‘AI’ with any other technological change that's happened in the last 30 years. It's the same kind of trend and processes and characteristics that you need in your leadership to implement the technology appropriately to get the outcomes that you're looking for.”
Which means, for pharma, much uncertainty and much experimentation.
“I think experimentation is good,” says Eng, who then adds that we need to always keep track of what is it that we're experimenting on. She says that the word “experimentation” can “sound very fluid” but in fact, “It's a very structured process. You set up some very clear objectives and you either prove or don't prove those objectives.”
Waller references the various revolutions (throughput screening, combinational chemistry, data, and analytics revolutions) that pharma has seen and says: “We've all held out hope for each and every one of these revolutions that the drug discovery process is going to be shrunk by 50% and cost half as much. And every time we turn around, it's still 12 to 15 years, $1.5 to $2 billion.”
Will AI make the big difference, finally?
“Maybe we need to be revolutionized as an industry,” she says. “It can be hard to make much of a difference as long as there are few big players.” Just a few big players, she says, is “the nature of pharma.”
Of course, our scientists are measured in their assessments about industry change. After all, as Waller says, the systems involved—the human body, the regulatory environment, the commercial ecosystems—are all “super-complicated.”
Eng notes that an important side-effect around the AI hype is corporate interest in data. “Now it's much easier to put that topic on the table saying, ‘If you want to do AI, you need to take care of your data and you need to treat it like an asset.’”
Listen on as they test topics such as regional and regulatory challenges in AI adoption, change management, and future tech and long-term impact (watch out for quantum, everyone!).
In the end, Eng returns to the idea of revolutions. “You think you want so much change in the beginning which you don't get because it takes time,” says Eng. This makes us underestimate what will happen later. Having such a farseeing mindset is significant, she says, because “these technology shifts will have a large impact on the long term.”
Host: Alison Kotin
Engineer: Kyp Pilalas
Producer: Ken Gordon
