When it comes to the topic of drug discovery and development, scientists are busy furrowing their lab-goggled brows trying to understand what’s real and what’s hype when it comes to the power and potential of AI.
This *Resonance Test* conversation perfectly dramatizes the situation. In this episode, Emma Eng, VP of Global Data & AI, Development at Novo Nordisk, and scientist and strategist Chris Waller provide a candid view of drug development in the AI era.
“We're standing on a revolution,” says Eng, reminding us that “we've done it so many other times” with the birth of the computer and the birth of the internet. It’s prudent, she cautions, not to rush to judgement guided by either zealots or skeptics.
Waller says, of the articles about AI and leadership in *Harvard Business Review,* one could do “a search and replace ‘AI’ with any other technological change that's happened in the last 30 years. It's the same kind of trend and processes and characteristics that you need in your leadership to implement the technology appropriately to get the outcomes that you're looking for.”
Which means, for pharma, much uncertainty and much experimentation.
“I think experimentation is good,” says Eng, who then adds that we need to always keep track of what is it that we're experimenting on. She says that the word “experimentation” can “sound very fluid” but in fact, “It's a very structured process. You set up some very clear objectives and you either prove or don't prove those objectives.”
Waller references the various revolutions (throughput screening, combinational chemistry, data, and analytics revolutions) that pharma has seen and says: “We've all held out hope for each and every one of these revolutions that the drug discovery process is going to be shrunk by 50% and cost half as much. And every time we turn around, it's still 12 to 15 years, $1.5 to $2 billion.”
Will AI make the big difference, finally?
“Maybe we need to be revolutionized as an industry,” she says. “It can be hard to make much of a difference as long as there are few big players.” Just a few big players, she says, is “the nature of pharma.”
Of course, our scientists are measured in their assessments about industry change. After all, as Waller says, the systems involved—the human body, the regulatory environment, the commercial ecosystems—are all “super-complicated.”
Eng notes that an important side-effect around the AI hype is corporate interest in data. “Now it's much easier to put that topic on the table saying, ‘If you want to do AI, you need to take care of your data and you need to treat it like an asset.’”
Listen on as they test topics such as regional and regulatory challenges in AI adoption, change management, and future tech and long-term impact (watch out for quantum, everyone!).
In the end, Eng returns to the idea of revolutions. “You think you want so much change in the beginning which you don't get because it takes time,” says Eng. This makes us underestimate what will happen later. Having such a farseeing mindset is significant, she says, because “these technology shifts will have a large impact on the long term.”
Host: Alison Kotin
Engineer: Kyp Pilalas
Producer: Ken Gordon
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When it comes to the topic of drug discovery and development, scientists are busy furrowing their lab-goggled brows trying to understand what’s real and what’s hype when it comes to the power and potential of AI.
This *Resonance Test* conversation perfectly dramatizes the situation. In this episode, Emma Eng, VP of Global Data & AI, Development at Novo Nordisk, and scientist and strategist Chris Waller provide a candid view of drug development in the AI era.
“We're standing on a revolution,” says Eng, reminding us that “we've done it so many other times” with the birth of the computer and the birth of the internet. It’s prudent, she cautions, not to rush to judgement guided by either zealots or skeptics.
Waller says, of the articles about AI and leadership in *Harvard Business Review,* one could do “a search and replace ‘AI’ with any other technological change that's happened in the last 30 years. It's the same kind of trend and processes and characteristics that you need in your leadership to implement the technology appropriately to get the outcomes that you're looking for.”
Which means, for pharma, much uncertainty and much experimentation.
“I think experimentation is good,” says Eng, who then adds that we need to always keep track of what is it that we're experimenting on. She says that the word “experimentation” can “sound very fluid” but in fact, “It's a very structured process. You set up some very clear objectives and you either prove or don't prove those objectives.”
Waller references the various revolutions (throughput screening, combinational chemistry, data, and analytics revolutions) that pharma has seen and says: “We've all held out hope for each and every one of these revolutions that the drug discovery process is going to be shrunk by 50% and cost half as much. And every time we turn around, it's still 12 to 15 years, $1.5 to $2 billion.”
Will AI make the big difference, finally?
“Maybe we need to be revolutionized as an industry,” she says. “It can be hard to make much of a difference as long as there are few big players.” Just a few big players, she says, is “the nature of pharma.”
Of course, our scientists are measured in their assessments about industry change. After all, as Waller says, the systems involved—the human body, the regulatory environment, the commercial ecosystems—are all “super-complicated.”
Eng notes that an important side-effect around the AI hype is corporate interest in data. “Now it's much easier to put that topic on the table saying, ‘If you want to do AI, you need to take care of your data and you need to treat it like an asset.’”
Listen on as they test topics such as regional and regulatory challenges in AI adoption, change management, and future tech and long-term impact (watch out for quantum, everyone!).
In the end, Eng returns to the idea of revolutions. “You think you want so much change in the beginning which you don't get because it takes time,” says Eng. This makes us underestimate what will happen later. Having such a farseeing mindset is significant, she says, because “these technology shifts will have a large impact on the long term.”
Host: Alison Kotin
Engineer: Kyp Pilalas
Producer: Ken Gordon
The Resonance Test 91: Open Source with Christopher Spalding, Rachel Fadlon, and Chris Howard
The EPAM Continuum Podcast Network
30 minutes 54 seconds
1 year ago
The Resonance Test 91: Open Source with Christopher Spalding, Rachel Fadlon, and Chris Howard
“Open source” is, of course, a technology term. But, as it turns out, when you connect tech-minded people with those who don’t necessarily think of themselves as IT nerds, something magical can happen. In this case, what works in the digital world—transparency, community, collaboration—has a funny way of spilling over into the analog world. Because, well, people are people. We’re wired to connect.
In today’s episode of *The Resonance Test,* open source sage Chris Howard chats up two open source experts from EBSCO Information Services: Christopher Spalding, Vice President of Product, and Rachel Fadlon, Vice President of SaaS Marketing and National Conferences & Events. EBSCO is a founding member of Folio, an open source library services platform (LSP), to which EPAM contributes.
The Open Source Initiative (OSI) maintains a precise definition for the term, but in broad strokes, open source refers to software containing source code that can be edited and used by anyone. We all use it every day without realizing it. Indeed, open source powers the internet as we know it.
Howard asked Spalding and Fadlon to reflect on what open source has been like at EBSCO, so other companies and industries can learn from an open source project that has achieved scale.
Folio has allowed developers and librarians to work together in an unprecedented way. Being part of the Folio community, says Fadlon, has dramatically transformed the way EBSCO interacts with customers across the company.
The relationships that develop organically in an open source community, which are less formal and more “person to person,” says Fadlon, have influenced EBSCO to be more community-oriented in all aspects of the business.
“The way that you approach someone in the library as a community member *to* a community member is very different than the way we were approaching our customers before,” she says. “We’ve made a lot more things more transparent and open” since joining Folio.
Spalding says even the language has changed around communications more broadly. “The focus is on, ‘Well, why would that be closed? Let’s make that open. Why wouldn’t we talk about that?’ Let’s put it all on the table because we get feedback instantly, and then we know the direction that we go as a partnership with the larger community.”
Of course, the trio also talked about security and artificial intelligence, the latter playing out differently in different regions.
Open source made headlines recently when Linux, one of the most well-known examples of open source, narrowly avoided a cybersecurity disaster thanks to an eagle-eyed engineer. Open source comes with risks, like anything online. Spalding says security concerns might have pushed libraries away from open source a few years ago, but now, increasingly, libraries are adopting the open source adage: “More eyes, fewer bugs. And definitely, more eyes, better security.”
Howard agrees. “We shouldn’t be afraid of having all of those eyes on us… One of my developers calls it kind of ‘battle testing’ the software, throwing it out to the world and saying, ‘Does this do what you want it to do?’ And if it doesn’t, at least you can tell me … and I can go and fix it or you can even fix it for me if you want to. And I think we’re now finding more and more organizations that actually find that more attractive than scary.”
Open yourself up to a more flexible, transparent future by listening to this engaging conversation.
Host/Producer: Lisa Kocian
Engineer: Kyp Pilalas
Executive Producer: Ken Gordon
The EPAM Continuum Podcast Network
When it comes to the topic of drug discovery and development, scientists are busy furrowing their lab-goggled brows trying to understand what’s real and what’s hype when it comes to the power and potential of AI.
This *Resonance Test* conversation perfectly dramatizes the situation. In this episode, Emma Eng, VP of Global Data & AI, Development at Novo Nordisk, and scientist and strategist Chris Waller provide a candid view of drug development in the AI era.
“We're standing on a revolution,” says Eng, reminding us that “we've done it so many other times” with the birth of the computer and the birth of the internet. It’s prudent, she cautions, not to rush to judgement guided by either zealots or skeptics.
Waller says, of the articles about AI and leadership in *Harvard Business Review,* one could do “a search and replace ‘AI’ with any other technological change that's happened in the last 30 years. It's the same kind of trend and processes and characteristics that you need in your leadership to implement the technology appropriately to get the outcomes that you're looking for.”
Which means, for pharma, much uncertainty and much experimentation.
“I think experimentation is good,” says Eng, who then adds that we need to always keep track of what is it that we're experimenting on. She says that the word “experimentation” can “sound very fluid” but in fact, “It's a very structured process. You set up some very clear objectives and you either prove or don't prove those objectives.”
Waller references the various revolutions (throughput screening, combinational chemistry, data, and analytics revolutions) that pharma has seen and says: “We've all held out hope for each and every one of these revolutions that the drug discovery process is going to be shrunk by 50% and cost half as much. And every time we turn around, it's still 12 to 15 years, $1.5 to $2 billion.”
Will AI make the big difference, finally?
“Maybe we need to be revolutionized as an industry,” she says. “It can be hard to make much of a difference as long as there are few big players.” Just a few big players, she says, is “the nature of pharma.”
Of course, our scientists are measured in their assessments about industry change. After all, as Waller says, the systems involved—the human body, the regulatory environment, the commercial ecosystems—are all “super-complicated.”
Eng notes that an important side-effect around the AI hype is corporate interest in data. “Now it's much easier to put that topic on the table saying, ‘If you want to do AI, you need to take care of your data and you need to treat it like an asset.’”
Listen on as they test topics such as regional and regulatory challenges in AI adoption, change management, and future tech and long-term impact (watch out for quantum, everyone!).
In the end, Eng returns to the idea of revolutions. “You think you want so much change in the beginning which you don't get because it takes time,” says Eng. This makes us underestimate what will happen later. Having such a farseeing mindset is significant, she says, because “these technology shifts will have a large impact on the long term.”
Host: Alison Kotin
Engineer: Kyp Pilalas
Producer: Ken Gordon
