
In this powerful episode of the College of Glycation podcast, Dr. Paul Reynolds takes listeners deep into the hidden world of glycation and its devastating impact on kidney health. Building on previous episodes, Dr. Reynolds explains how advanced glycation end products (AGEs) silently damage the kidneys—compromising filtration, triggering chronic inflammation, and accelerating the march toward chronic kidney disease and dialysis. With clarity and urgency, he exposes how insulin resistance and elevated blood sugar fuel this process, creating a vicious metabolic cycle that threatens millions worldwide.
Grounded in peer-reviewed science and rich historical context, this episode also explores emerging diagnostic tools like skin autofluorescence and highlights practical strategies to reduce AGE burden through diet, cooking methods, and lifestyle changes. Whether you're navigating diabetes or simply aiming to protect your long-term kidney function, this episode is a must-listen for anyone seeking to understand and interrupt the silent sabotage of glycation.