Redefining the Undruggable Through Proximity with Armand Cognetta

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The Bits in Bio Podcast

Robbie Matthews and Vincent Alessi

3 episodes

4 days ago

Hosts Robbie and Vince explore techbio’s hidden machinery—venture hype, lab experiments, and algorithmic dreams—to reveal what works, what spectacularly fails, and the stubborn realities of turning code into biology.

Technology

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Technology

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Redefining the Undruggable Through Proximity with Armand Cognetta

The Bits in Bio Podcast

36 minutes 23 seconds

1 week ago

Redefining the Undruggable Through Proximity with Armand Cognetta

Armand Cognetta, founder and CEO of General Proximity, joins us to explore how proximity medicine is revolutionizing drug discovery by targeting proteins once considered impossible to drug.

We discuss the evolution beyond PROTACs, being a solo bio-founder in Y Combinator, and Armand's journey from imposter syndrome to raising $16M and winning a $3M ARPA-H grant.

From nearly running out of money to building breakthrough platform technology, Armand shares hard-won lessons on fundraising, team building, and maintaining startup speed in an industry known for decade-long timelines.