In this episode of Talking Techniques, Rachel Thijssen, an Assistant Professor at Amsterdam University Medical Centers (UMC; the Netherlands), discusses her research using single-cell analyses to investigate treatment-resistant leukemia cells. Rachel explains her single-cell technique called rapid capture hybridization sequencing (RaCH-seq), how she utilizes nanopore sequencing, and how she hopes that this technique can be used to gain new insights into disease and improve therapies.

Contents:

00:00–01:35: Introduction

01:35–03:25: Single-cell sequencing in leukemia research

03:25–05:15: What is single-cell RaCH-seq?

05:15–06:10: Using nanopore sequencing for RaCH-seq

06:10–07:30: How can other researchers apply RaCH-seq to their work?

07:30–09:50: Looking to the future: spatial biology, collaborations and improved therapies 

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