In this episode of the Talking Biotech podcast, Dr. Andrey Zarur, CEO of Greenlight Biosciences, discusses the innovative applications of RNA technology in agriculture. The conversation covers the challenges of food security, the role of RNA in pest control, and the regulatory advantages of RNA-based products. Dr. Zarur highlights the efficacy and safety of RNA insecticides, fungicides, and herbicides, as well as the company's efforts to address bee health. The discussion also touches on public perception and the importance of transparent communication in biotechnology.
00:00
Introduction to RNA and Its Role in Agriculture
02:02
Challenges in Global Food Production
05:07
The Promise of RNA Technology
10:05
Regulatory Landscape for RNA-Based Solutions
13:52
Stability and Application of RNA Products
18:00
Product Development and Efficacy of RNA Pesticides
19:48
Targeting Specific Pests with RNA Technology
26:51
AI in RNA Design and Future Prospects
30:01
Innovative Approaches to Pest Control
32:41
Targeting Specific Pests with RNA Technology
35:22
Challenges in Regulatory Approval and Public Perception
38:02
Engaging with the Public and NGOs
42:46
Addressing the Varroa Mite Crisis in Beekeeping
49:18
Developing RNA Solutions for Weed Management
Summary
In this episode of the Talking Biotech podcast, Dr. Kevin Folta interviews Dr. Robert Tarone, a retired scientist with extensive experience in cancer statistics and experimental design. They discuss the controversial IARC monograph that classified glyphosate as a probable human carcinogen, the flaws in the evaluation process, and the implications of this classification on legal actions against glyphosate manufacturers. Dr. Tarone critiques the evidence used by IARC, emphasizing the lack of credible data linking glyphosate to cancer, and highlights the importance of rigorous scientific methodology in evaluating such claims.
In this episode of the Talking Biotech podcast, Kevin Folta and Dr. David Zaruk discuss the complexities surrounding glyphosate, particularly in light of the IARC Monograph 112 published a decade ago. They explore the implications of the reclassification of glyphosate as a probable carcinogen, the ensuing litigation, influence and corruption, and the ethical concerns regarding scientific integrity. The conversation delves into the role of the media, the influence of litigation finance, and the future of glyphosate in agriculture, emphasizing the need for transparency and evidence-based discussions over jury decisions.
This conversation explores the domestication of pigs, highlighting their importance in human society, the historical evidence of their domestication, and innovative research methods used to study their relationship with humans. Dr. Jiajing Wang from Dartmouth College discusses the significance of dental calculus in elucidaing pig diets and behaviors, as well as the complex interactions between humans and pigs throughout history.
In this episode of the Talking Biotech podcast, Dr. Kevin Folta speaks with Dr. Pascal Geldsetzer about the relationship between the shingles vaccine and dementia. They discuss the prevalence of shingles, the current vaccination rates, and the potential implications of shingles vaccination on cognitive decline. The data come from a clever analysis of public health data that revealed this surprising result. Dr. Geldsetzer shares insights from his research, which suggests that the shingles vaccine may significantly reduce the risk of developing dementia. The conversation also covers the methodology behind the research, findings from various populations, and future directions for further studies in this area.
Summary
In this episode of the Talking Biotech Podcast, Kevin Folta speaks with Maria Rodtersman, a Ph.D. candidate at UC Davis, about her research on developing wheat to reduce gluten content, specifically targeting immunogenic proteins that trigger celiac disease. They discuss the significance of wheat as a staple crop, the differences between celiac disease and gluten sensitivity, and the use of radiation-induced mutations, the old-school brute force genetic methods used to create wheat lines with lower immunogenicity. The conversation also covers the challenges of wheat's hexaploid nature, the testing of modified wheat for bread quality and immunogenicity, and the future directions of this research.
Bluesky @dubcovskylab.bsky.social
The elucidation of DNA's structure led to questions about how it was replicated. Today's Talking Biotech Podcast commemorates the landmark experiments by Dr. Franklin Stahl, who died recently at the age of 95. The experiments have beed described as amont the most elegant in the history of biology, and used a simple test to determine the physical nature of DNA replication. This is a must-know story for the molecular biologist, and a spectacular example of a clever and definitive experiment for anyone that appreciates science.
In this episode of the Talking Biotech Podcast, Dr. Kevin Folta discusses the challenges of misinformation in food science with Dr. Cami Ryan and registered dietitian Connie Diekman. They explore the role of social media and traditional media in spreading misinformation, the difficulties scientists face in communicating effectively, and the importance of peer review and other information-honing strategies to reinforce legitimate claims and de-fuse false information. The conversation emphasizes the need for better communication strategies, building trust with the public, and the necessity of teaching critical thinking and media literacy to consumers.
In this episode of the Talking Biotech Podcast (464) host Dr. Kevin Folta engages with journalist and author Michael Grunwald about his book 'We Are Eating the Earth.' They discuss the complex relationship between food production, climate change, and biotechnology, emphasizing the need for multifaceted solutions rather than single silver bullet approaches. Grunwald shares insights from his journey into understanding food production's impact on the environment, agroecology and regenerative farming, the challenges of public perception regarding biotechnology, and the importance of innovative practices in agriculture. The conversation also touches on the issues of food waste, biofuels, and the necessity for government investment in agricultural research and technology.
You can buy Mike's book here: https://www.simonandschuster.com/books/We-Are-Eating-the-Earth/Michael-Grunwald/
In this episode of the Talking Biotech podcast, Dr. Roger Cone discusses the complexities of obesity and eating disorders, emphasizing the role of brain circuits in regulating feeding behaviors. He explains the significance of GLP-1 agonists and melanocortin receptors in developing therapeutic approaches for conditions like obesity, anorexia, and cachexia. The conversation highlights the potential of combining these therapies to enhance treatment efficacy and the implications for public health. But most importantly, the approaches offer potential new therapies to address anorexia and cachexia that may prove to be as effective as GLP1 agonists have been for addressing obesity.
This episode of the Talking Biotech podcast features Dr. Anita Shukla discussing the critical issue of antibiotic resistance and the innovative engineering solutions being explored to combat it. The conversation covers the evolutionary nature of antimicrobial resistance (AMR), the importance of antibiotics in healthcare, and the collaborative efforts of the Engineering Research Visioning Alliance (ERVA) to identify research priorities and strategies. Dr. Shukla emphasizes the need for novel therapeutic approaches, improved drug delivery systems, and the integration of advanced detection methods to address the growing challenge of AMR.
In this episode of the Talking Biotech podcast, Dr. Kevin Folta interviews Dr. Sarah Taber, who shares her journey from agricultural consulting to running for Ag Secretary in North Carolina. It is mostly a story of dedication to changing the norms and changing the rules to benefit more farmers, trying to break deeply entrenched interests to create real change. The conversation explores the challenges facing North Carolina agriculture, the need for innovative ideas to shift from traditional crops to more profitable produce, and the political landscape that influences agricultural policies. Sarah discusses her motivations for running, the strategies she employed during her campaign, and the lessons learned from the experience. The episode concludes with insights on the future of agriculture in North Carolina and advice for aspiring politicians.
In this episode of the Talking Biotech podcast, Dr. Kevin Folta discusses the current state of avian influenza, particularly the H5N1 strain, its history, zoonotic potential, and the implications for both poultry and human health. Into 2025 it was being detected in wild birds,domestic flocks, cattle and humans. Where did it go? He highlights the importance of surveillance, the impact of the virus on domestic poultry production, and the ethical concerns surrounding euthanization methods. Folta also explores potential solutions, including vaccination and transgenic strategies that go unused although they are known to be effective. Finally, what is the status of emergency response? The strategic stockpiles are gone, new mRNA strategies have been defunded. With no desire to protect animals and government policy failing to take precautions to protect humans, an avian influenza pandemic may be devastating. The current situation is discussed.
This episode of the Talking Biotech podcast delves into the evolutionary significance and domestication history of corn (maize). Dr. Kevin Folta hosts a discussion with Regina Fairbanks and Dr. Jeffrey Ross-Ibarra from UC Davis, exploring the traits that enabled maize's domestication, the role of the TGA gene, and the implications for modern breeding. The conversation highlights the importance of understanding maize's genetic diversity and how modern tools may be used to unravel long standing questions about maize domestication.
In this episode of the Talking Biotech podcast, Kevin Folta and Luis Ventura discuss the recent constitutional ban on genetically engineered corn in Mexico. They explore the implications of this regulation, the disinformation surrounding it, and the challenges faced by Mexican farmers. The conversation also touches on the broader impact of this ban on biotechnology in Latin America and the potential economic consequences for trade between Mexico and the United States.
This conversation explores the complex relationship between corn and Mexico, focusing on its cultural, economic, and agricultural significance. The discussion highlights the moratorium on genetically engineered (GM; GMO) corn, the public perception of biotechnology, and the impact of environmental NGOs on policy decisions. The conversation also delves into the perspectives of farmers regarding the need for access to biotechnology and the implications of recent presidential decrees on corn production in Mexico.
This conversation explores the intersection of natural products and synthetic biology, emphasizing the importance of science communication and outreach. Julia Ball shares her passion for connecting the public with plant science, while Dr. Philip Zerbe discusses the potential of synthetic biology in producing valuable natural products, particularly terpenoids. The discussion highlights the challenges and opportunities in educating the public about biotechnology and the role of synthetic biology in sustainable drug production. In this conversation, Dr. Philipp Zerbe discusses the intersection of synthetic biology and natural products, focusing on the advancements in omics technologies and their role in bioactivity screening and pathway engineering. He highlights the recent breakthroughs in Taxol production, the complexities of intellectual property in synthetic biology, and the varying consumer perceptions of bioengineered products. Additionally, he provides insights into career guidance for students interested in these fields, emphasizing the importance of hands-on experience and networking.
In this episode of the Talking Biotech podcast, Dr. Kevin Folta speaks with Steph van Grieken, CEO of Cradle, about the revolutionary intersection of AI and protein engineering. They discuss the central role of proteins in biological systems, the innovative software Cradle is developing to enhance protein design, and the implications of these advancements for therapeutics and industrial applications. The conversation also touches on the ethical considerations and potential misuse of this technology, as well as the future of AI in biology and its impact on environmental sustainability.
In this episode of the Talking Biotech podcast, Dr. Kevin Folta discusses the introduction of the Purple Tomato by Norfolk Healthy Produce. Dr. Nathan Pumplin, CEO of Norfolk Healthy Produce, shares insights on the development, consumer reception, and regulatory landscape surrounding this innovative product. The conversation highlights the importance of consumer education and the potential for biotechnology to address health and nutritional needs. Dr. Pumplin discusses the technology and genetic engineering involved, the importance of plant breeding, and the health benefits associated with anthocyanins. He emphasizes the company's commitment to creating high-quality products while addressing public perceptions of GMOs and the future of biotechnology in agriculture.
Social media teems with false information about food and farming. Influencers cover Instagram and Facebook with claims that food is poison and farmers are "dousing" crops in dangerous chemicals. It is a disinformation campaign that is founded on the fact that Americans make poor food and lifestyle choices, but instead of blaming our behaviors, they blame food and medicine, pushing bogus high-profit alternatives. But is there something nefarious here? Has this online suspicion of our medical and food systems seeded by interests wishing to turn citizens against farmers and regulators, opting instead for fake alternatives and bogus nostrums? It is a viable hypothesis. The war on seed oils, glyphosate and genetically engineered crops has re-ignited, despite minimal, if any, risk. Senate testimony by podcaster and "integrative nutritionist" Courtney Swan is dissected to demonstrate how wildly incorrect these folks are-- when speaking before a US Senate commitee! This is how disinformation spread and now is being used to influence the highest eschelons of federal government. This all appears to be science and reason losing a damaging disinformation campaign using the internet and its complicit influencers to harm food and national security.
