In this episode, I sit down with Dr. Chris Rhodes, metabolic scientist and co-founder of Mimio, to explore the next frontier in fasting and longevity. We unpack the real science behind what happens during a fast , from autophagy to inflammation, and how Mimio, a fasting mimetic, is engineered to replicate these profound benefits without requiring prolonged food restriction.

Dr. Rhodes explains how Mimio was developed by analyzing blood samples from individuals in extended fasts, identifying key signaling molecules, and recreating their cellular effects in supplement form. We discuss the nuanced differences in fasting responses between men and women, the impact of fasting on cognitive and hormonal health, and how Mimio may help extend the metabolic benefits of shorter fasting windows.

Whether you're deep into fasting protocols or new to the concept of metabolic switching, this conversation delivers practical insights and cutting-edge science on how to optimize your biology with or without skipping meals.

• The physiological phases of fasting and why timing matters

• How Mimio replicates the cellular effects of a 36-hour fast

• The role of autophagy, inflammation, and energy metabolism

• Why fasting responses vary by sex and hormonal profile

• Cognitive and mood benefits associated with fasting molecules

• The specific ingredients in Mimio and how they work

• Appetite regulation and satiety improvements observed in studies

• Safety, contraindications, and what to know before using fasting mimetics

• The emerging science of metabolic signaling and future directions

• Fasting has been shown to extend lifespan significantly in animal models

• Mimio is designed to capture the cellular benefits of a 36-hour fast

• Different fasting durations trigger distinct metabolic benefits

• Fasting mimetics can help amplify results from shorter fasts

• Mimio’s ingredients are selected for their anti-inflammatory and regenerative properties

• Users have reported cognitive clarity and improved focus with Mimio

• Female fasting responses may vary due to menstrual cycle phases and hormone fluctuations

• Fasting supports metabolic health and reduces chronic inflammation

• Clinical research shows Mimio improves appetite control and feelings of satiety

• Ongoing studies aim to expand the fasting mimetic category with new compounds

If you’re serious about enhancing your healthspan, curious about fasting, and want your cells to perform optimally as you age, this clinically proven supplement is the ultimate biohack for you. Visit mimiohealth.com/sweatyaf and use code SWEATYAF for 20% off your first order of Mimio’s Biomimetic Cell Care supplement.