E5   |   14 min   |   Latest   |  Publication Source    Podcast based on: Sipos D, Raposa BL, Freihat O, Simon M, Mekis N, Cornacchione P, Kovács Á. Glioblastoma: Clinical Presentation, Multidisciplinary Management, and Long-Term Outcomes. Cancers. 2025; 17(1):146. https://doi.org/10.3390/cancers17010146Type: Review  |  Publication date: Jan 5, 2025 Summary: This document comprehensively examines glioblastoma, the most aggressive form of brain cancer. It details the disease's diagnosis, utilising advanced imaging and molecular markers like IDH mutation and MGMT methylation status for prognosis. Standard treatment, involving surgery, radiation, and chemotherapy (temozolomide), is discussed alongside emerging therapies such as TTFields and immunotherapies. The text also addresses the importance of managing symptoms and providing psychological support for patients and their families to improve quality of life, while acknowledging the ongoing need for research and clinical trials to improve outcomes. Finally, typical survival rates and factors influencing prognosis are presented. Keywords: glioblastoma; prognosis; treatment; survival; outcome Disclaimer: The content of this podcast is a summary and discussion of the original publication and does not represent the views of the authors or journal. The information shared here is intended for educational purposes only and does not constitute clinical advice or recommendations. It also uses AI-assisted summaries of the original work and may or may not contain innacuracies so we encourage listeners to consult the original publication for complete details.