In 1846, Dr. John Collins Warren and William T. G. Morton performed the first public demonstration of surgery under an anesthetic. Today, anesthesiologist and statistician Emery Brown combines his fields of expertise and applies a computational approach to answer questions about neuroscience and to research how anesthetics interact with the central nervous system. Brown is a faculty member at Massachusetts General Hospital, Harvard, and MIT, and in this episode, he highlights that, while anesthesia practices in the operating room have evolved over the 175 years since Warren and Morton’s first anesthesia demonstration, medical understanding of how anesthetics work is still limited. His work pioneers a new approach to administering anesthetics to patients—by reading and using electrical activity in the brain to determine the appropriate dose of anesthetic. Brown’s curiosity is inspiring, as his exploration of diverse interests expands beyond biomedicine to foreign languages—in this episode, he also speaks on his approach to language learning and how he utilizes language learning in a clinical context. Music by Kevin MacLeod licensed under CC BY 4.0.