Valproic Acid for ICU Delirium: A New Tool for Agitation Management?

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Saving Lives Podcast: Critical Care w/eddyjoemd

Eddy Joe Gutierrez, MD

159 episodes

2 days ago

Saving Lives Podcast: Critical Care w/eddyjoemd is a podcast that reviews evidence-based strategies to care for the critically ill patient in the Intensive Care Unit and other topics in Medicine. It is hosted by Eddy Joe Gutierrez, MD, a board-certified critical care physician. In each episode, Dr. Gutierrez discusses the latest research and best practices in Intensive Care Medicine. He also shares his own insights and experiences as an Intensivist/Critical Care physician. The podcast is designed for healthcare professionals who want to stay up-to-date with evidence-based medicine.

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Health & Fitness

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Saving Lives Podcast: Critical Care w/eddyjoemd is a podcast that reviews evidence-based strategies to care for the critically ill patient in the Intensive Care Unit and other topics in Medicine. It is hosted by Eddy Joe Gutierrez, MD, a board-certified critical care physician. In each episode, Dr. Gutierrez discusses the latest research and best practices in Intensive Care Medicine. He also shares his own insights and experiences as an Intensivist/Critical Care physician. The podcast is designed for healthcare professionals who want to stay up-to-date with evidence-based medicine.

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Health & Fitness

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Valproic Acid for ICU Delirium: A New Tool for Agitation Management?

Saving Lives Podcast: Critical Care w/eddyjoemd

6 minutes 9 seconds

4 months ago

Valproic Acid for ICU Delirium: A New Tool for Agitation Management?

In this episode of the Saving Lives Podcast, we reviews a 2024 multicenter study on valproic acid for hyperactive delirium and agitation in ICU patients. The findings show that VPA may help reduce sedation needs, improve ventilator synchrony, and resolve delirium without major adverse effects. Tune in for practical insights into this emerging option for complex critical care cases.

The Vasopressor & Inotrope Handbook

I have written "The Vasopressor & Inotrope Handbook: A Practical Guide for Healthcare Professionals," a must-read for anyone caring for critically ill patients (check out the reviews)! You have several options to get a physical copy.

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Citation: Nuti O, Merchan C, Ahuja T, Arnouk S, Papadopoulos J, Katz A. Valproic Acid for Hyperactive Delirium and Agitation in Critically Ill Patients. J Intensive Care Med. 2025 May;40(5):519-527. doi: 10.1177/08850666241302760. Epub 2024 Dec 8. PMID: 39648603.