The RMD Open podcast offers the latest insights in musculoskeletal disorders, rheumatism and connective tissue diseases. Each episode features in-depth interviews with authors and leading experts, discussing the latest research and treatments in the field.
RMD Open - rmdopen.bmj.com - is an esteemed international journal from the BMJ Group publishing original research on the full spectrum of musculoskeletal disorders, rheumatism and connective tissue diseases, including osteoporosis, spine and rehabilitation.
Stay ahead in your field by tuning into our expert discussions and accessing cutting-edge content.
* The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.
All content for RMD Open Podcast is the property of BMJ Group and is served directly from their servers
with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.
The RMD Open podcast offers the latest insights in musculoskeletal disorders, rheumatism and connective tissue diseases. Each episode features in-depth interviews with authors and leading experts, discussing the latest research and treatments in the field.
RMD Open - rmdopen.bmj.com - is an esteemed international journal from the BMJ Group publishing original research on the full spectrum of musculoskeletal disorders, rheumatism and connective tissue diseases, including osteoporosis, spine and rehabilitation.
Stay ahead in your field by tuning into our expert discussions and accessing cutting-edge content.
* The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.
Interleukin-17: a role in inflammatory arthritis and implication for clinical practice
RMD Open Podcast
13 minutes 34 seconds
8 years ago
Interleukin-17: a role in inflammatory arthritis and implication for clinical practice
Interleukin-17 (IL-17A) is a cytokine critical for the acute defence against extracellular bacterial and fungal infections. Excess production during chronic inflammation has been associated with many inflammatory and autoimmune disorders.
In this podcast, the Editor-in-Chief of RMD Open Bernard Combe and Pierre Miossec (Department of Immunology and Rheumatology, University of Lyon, France) discuss a review paper about an update on IL-17A.
The review concludes that the use of IL-17 inhibition in psoriatic arthritis (PsA) is easy to understand because of the role of IL-17 in bone destruction. However, the use of the same inhibitors for the treatment of ankylosing spondylitis (AS) implies another understanding. In fact, IL-17 specifically in combination with TNF, induces bone matrix formation by isolated osteoblasts. This is the case at the site of ligaments insertion, where osteoclasts are absent. Local bone formation leads to syndesmophytes.
Professor Miossec also explains how these findings might impact clinical practice.
For more details about this article, visit the RMD Open website: http://rmdopen.bmj.com/content/3/1/e000284.
RMD Open Podcast
The RMD Open podcast offers the latest insights in musculoskeletal disorders, rheumatism and connective tissue diseases. Each episode features in-depth interviews with authors and leading experts, discussing the latest research and treatments in the field.
RMD Open - rmdopen.bmj.com - is an esteemed international journal from the BMJ Group publishing original research on the full spectrum of musculoskeletal disorders, rheumatism and connective tissue diseases, including osteoporosis, spine and rehabilitation.
Stay ahead in your field by tuning into our expert discussions and accessing cutting-edge content.
* The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.
