In this episode of the Research Forward podcast, host David Mayo interviews Adrian Zeltner, a leading expert in mini pig care, handling, anesthesia, and surgery, with extensive experience in the pharmaceutical and biomedical research industries. Adrian shares his unique career journey, from his beginnings in Switzerland to his time in New Zealand and eventual move to Denmark, where he became deeply involved in mini pig research.The conversation delves into the various applications of mini pigs in biomedical research, highlighting their anatomical and physiological similarities to humans, which make them valuable models for studying cardiovascular diseases, diabetes, obesity, and dermatological conditions. Adrian explains the benefits of using mini pigs, including their manageable size and the ethical considerations in their care and use.They also discuss the importance of proper handling, dosing, and training techniques to ensure animal welfare and the accuracy of research outcomes. Adrian emphasizes the role of continuous professional development and the need for refined surgical and anesthetic procedures to minimize stress and improve data quality.The episode concludes with Adrian's insights on the future of biomedical research, advocating for the reduction and eventual elimination of animal use through advancements in alternative methods and technologies. This episode provides a comprehensive overview of the critical role mini pigs play in advancing medical science and the ongoing efforts to enhance animal welfare in research.