Professors Bas Bloem and Werner Poewe discuss the practical management of re-emergent symptoms in Parkinson’s disease, offering expert insights and guidance on how to recognise, assess, and address these challenges in daily clinical practice.
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Professors Bas Bloem and Werner Poewe discuss the practical management of re-emergent symptoms in Parkinson’s disease, offering expert insights and guidance on how to recognise, assess, and address these challenges in daily clinical practice.
S1 EP2: Motor Fluctuations and the levodopa long-duration response
Reflections on Parkinson's Disease
16 minutes
4 years ago
S1 EP2: Motor Fluctuations and the levodopa long-duration response
In this episode, Bas and Werner delve into the term ‘motor fluctuations’ which is linked to the long-term experience patients have with Levodopa. They discuss a study by George Cotzias regarding the ‘intermittency in the action of the drug’, what the term ‘wearing off’ stands for and the differences between a short-duration/long-duration response.
Reflections on Parkinson's Disease
Professors Bas Bloem and Werner Poewe discuss the practical management of re-emergent symptoms in Parkinson’s disease, offering expert insights and guidance on how to recognise, assess, and address these challenges in daily clinical practice.