Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Eric Christianson, PharmD; Pharmacology Expert and Clinical Pharmacist
397 episodes
4 days ago
Pharmacology is one of the most challenge topics you will encounter as a healthcare professional, but it can be the most rewarding with a good understanding. Whether you are preparing to be a nurse, physician, physician assistant, pharmacist, dentist, nurse practitioner, pharmacy technician, pharmacologist, or other healthcare professional, this podcast will help you better understand pharmacology. In addition to giving you the basics like mechanism of action, side effects, drug interactions, etc., you will also be exposed to how medications actually impact patients in real life. In the Real Life Pharmacology podcast, Eric Christianson, PharmD shares his real world experiences about how a medication's mechanism of action, pharmacokinetics, adverse effects, and drug interactions can actually impact patients in both a positive and a potentially negative way. Eric Christianson PharmD is the author of the popular clinical pharmacy blog Meded101.com. People who are passionate about nursing, medicine, or pharmacy will find this podcast beneficial in helping them prepare for passing exams. This podcast is for educational purposes only and is not medical advice or intended to be a substitute for medical advice. Please seek advice from your pharmacist or primary care provider if you have questions about medications that you are taking.
All content for Real Life Pharmacology - Pharmacology Education for Health Care Professionals is the property of Eric Christianson, PharmD; Pharmacology Expert and Clinical Pharmacist and is served directly from their servers
with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.
Pharmacology is one of the most challenge topics you will encounter as a healthcare professional, but it can be the most rewarding with a good understanding. Whether you are preparing to be a nurse, physician, physician assistant, pharmacist, dentist, nurse practitioner, pharmacy technician, pharmacologist, or other healthcare professional, this podcast will help you better understand pharmacology. In addition to giving you the basics like mechanism of action, side effects, drug interactions, etc., you will also be exposed to how medications actually impact patients in real life. In the Real Life Pharmacology podcast, Eric Christianson, PharmD shares his real world experiences about how a medication's mechanism of action, pharmacokinetics, adverse effects, and drug interactions can actually impact patients in both a positive and a potentially negative way. Eric Christianson PharmD is the author of the popular clinical pharmacy blog Meded101.com. People who are passionate about nursing, medicine, or pharmacy will find this podcast beneficial in helping them prepare for passing exams. This podcast is for educational purposes only and is not medical advice or intended to be a substitute for medical advice. Please seek advice from your pharmacist or primary care provider if you have questions about medications that you are taking.
Real Life Pharmacology - Pharmacology Education for Health Care Professionals
13 minutes 18 seconds
1 week ago
Piperacillin/Tazobactam Pharmacology
Zosyn (piperacillin/tazobactam) is a broad-spectrum β-lactam/β-lactamase inhibitor combination used widely in hospitals. Piperacillin covers gram-positive, gram-negative, and anaerobic bacteria, while tazobactam helps protect against β-lactamase breakdown. It is commonly used for pneumonia, intra-abdominal infections, skin and soft tissue infections, and febrile neutropenia. An important pharmacology pearl for exams is understanding that Pseudomonas, but it doesn't cover MRSA.
The drug is renally eliminated, so dosing adjustments are needed in kidney impairment. Many institutions use extended or prolonged infusions to maximize time above the MIC, which can improve efficacy. Standard dosing is 3.375 g to 4.5 g every 6–8 hours, with modifications for dialysis patients.
Adverse effects include hypersensitivity, gastrointestinal upset, electrolyte imbalances like hypokalemia, and blood count changes with prolonged therapy. A key clinical concern is nephrotoxicity risk, especially when used with vancomycin. Monitoring renal function and electrolytes are important.
Methotrexate and probenecid are two medications that can interact with Zosyn. Concentrations of Zosyn can be increased when these medications are used in combination.
Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Pharmacology is one of the most challenge topics you will encounter as a healthcare professional, but it can be the most rewarding with a good understanding. Whether you are preparing to be a nurse, physician, physician assistant, pharmacist, dentist, nurse practitioner, pharmacy technician, pharmacologist, or other healthcare professional, this podcast will help you better understand pharmacology. In addition to giving you the basics like mechanism of action, side effects, drug interactions, etc., you will also be exposed to how medications actually impact patients in real life. In the Real Life Pharmacology podcast, Eric Christianson, PharmD shares his real world experiences about how a medication's mechanism of action, pharmacokinetics, adverse effects, and drug interactions can actually impact patients in both a positive and a potentially negative way. Eric Christianson PharmD is the author of the popular clinical pharmacy blog Meded101.com. People who are passionate about nursing, medicine, or pharmacy will find this podcast beneficial in helping them prepare for passing exams. This podcast is for educational purposes only and is not medical advice or intended to be a substitute for medical advice. Please seek advice from your pharmacist or primary care provider if you have questions about medications that you are taking.
