Polyweb explores the intersection of technology, startup, and human creativity.
Learn from top entrepreneurs and innovators about building companies that make an impact and living fulfilled lives in our modern, tech-focused society.
Hosted on Acast. See acast.com/privacy for more information.
Polyweb explores the intersection of technology, startup, and human creativity.
Learn from top entrepreneurs and innovators about building companies that make an impact and living fulfilled lives in our modern, tech-focused society.
Hosted on Acast. See acast.com/privacy for more information.

We all know it, even if we try our best not to dwell on it: one day, we will age and eventually die. Or will we?
Sara engages in a conversation with Sebastian Brunemeier to explore the potential reversal of aging and the prospect of avoiding death.
Sebastian Brunemeier is a General Partner at Healthspan Capital, a venture fund focused on longevity biotech and regenerative medicine. He is also CEO of ImmuneAGE Bio, a drug discovery platform for immune system rejuvenation. He was previously co-founder and CIO at Cambrian Biopharma, one of the largest longbio companies, Founder and COO of Samsara Therapeutics, a clinical-stage autophagy drug discovery company in Oxford UK, and Principal at Apollo Health Ventures, the largest aging-focused venture fund with 200M under management. He was a Fulbright Scholar on telomere biology, holds a master's degree in molecular neuroscience and biotech business management from the University of Amsterdam, and was in the PhD program on the biochemistry of aging at Oxford as a Clarendon scholar before dropping out to launch Cambrian. He is an advisor to several companies including VitaDAO, the longevity DAO
00:00 Introduction
01:35 Understanding the connection between aging and mortality
07:26 The pursuit of biological immortality
11:24 Strategies for prolonging life
15:45 Promising areas of research in the field of longevity
24:10 Exploring autophagy during fasting
26:03 Sebastian's personal longevity regimen
28:05 Overrated and underrated aspects of longevity research
32:29 Gender disparities in longevity studies
35:17 Contributing to longevity research efforts
37:28 Web3 and its intersection with biotech
42:00 Should we truly extend human lifespan? Examining the downsides and longevity dividends
48:39 The Vitalism movement
54:00 Societal transformations in a world without aging
01:02:03 The impact of an extended lifespan on birth rates
👉 CHECK OUT HEALTHSPAN CAPITAL: https://www.healthspancapital.vc/
📚 OTHER RESOURCES MENTIONED:
Samsara Therapeutics: https://www.samsaratherapeutics.com/
Bryan Johnson blueprint: https://blueprint.bryanjohnson.co/
Altos Labs: https://altoslabs.com/
Calico Labs: https://www.calicolabs.com/
VitaDAO: https://www.vitadao.com/
Zuzalu: https://zuzalu.city/
The Network State: https://thenetworkstate.com/
Niklas Anzinger’s “Stranded Technologies Podcast”: https://rss.com/podcasts/stranded-technologies-podcast/
The Longevity Dividend: https://amzn.to/3ppkuIf
Vitalism: https://www.vitalism.io/
🔗 CONNECT WITH SEBASTIAN :
👥 Linkedin - https://www.linkedin.com/in/sebastianaguiar/
📧 Email - sebastian@pantheonbio.org
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🐦 Twitter - https://twitter.com/Sara_LandiTor
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💌 Newsletter - https://saratortoli.substack.com/
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