Each episode of the Physiological Reviews podcast features commentary and discussion of newly published articles in the journal, which provides state-of-the-art, comprehensive, and high-impact coverage of timely issues in the physiological and biomedical sciences. Physiological Reviews articles appeal to physiologists, neuroscientists, cell biologists, biophysicists, and clinicians with special interest in pathophysiology. The journal is very useful in teaching and research because it provides non-biased and clearly written updates on important developments.
All content for Physiological Reviews Podcast is the property of American Physiological Society and is served directly from their servers
with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.
Each episode of the Physiological Reviews podcast features commentary and discussion of newly published articles in the journal, which provides state-of-the-art, comprehensive, and high-impact coverage of timely issues in the physiological and biomedical sciences. Physiological Reviews articles appeal to physiologists, neuroscientists, cell biologists, biophysicists, and clinicians with special interest in pathophysiology. The journal is very useful in teaching and research because it provides non-biased and clearly written updates on important developments.
Genome-wide Association Studies of Cardiovascular Disease
Physiological Reviews Podcast
23 minutes 51 seconds
2 years ago
Genome-wide Association Studies of Cardiovascular Disease
Genetics studies, including genome-wide association studies (GWAS), play an increasingly important role in physiology and pathophysiology studies of cardiovascular disease. Listen as Deputy Editor Dr. Carol Ann Remme interviews authors Prof. Jeanette Erdmann (University of Lübeck, Germany) and Prof. Connie Bezzina (Amsterdam University Medical Center, Netherlands) about their latest Review in Physiological Reviews by Walsh et al. GWAS are aimed at identifying genetic variants for specific traits, and it is essential to study genetic variants in order to understand an individual’s susceptibility to develop specific diseases. Understanding the genetic basis of a disease can lead to identification of therapeutic targets for clinical intervention. Listen as these experts discuss how GWAS can be applied to study both rare disorders, for example Brugada Syndrome, as well as common disorders such as myocardial infarction. The possibilities are numerous for GWAS, including the identification of novel pathophysiological insights into cardiovascular disease mechanisms, as well as (future) development of clinically applicable polygenic risk scores. Listen now to learn more.
Roddy Walsh, Sean J. Jurgens, Jeanette Erdmann, and Connie R. Bezzina Genome-wide association studies of cardiovascular disease Physiological Reviews, published April 18, 2023. DOI: 10.1152/physrev.00024.2022
Physiological Reviews Podcast
Each episode of the Physiological Reviews podcast features commentary and discussion of newly published articles in the journal, which provides state-of-the-art, comprehensive, and high-impact coverage of timely issues in the physiological and biomedical sciences. Physiological Reviews articles appeal to physiologists, neuroscientists, cell biologists, biophysicists, and clinicians with special interest in pathophysiology. The journal is very useful in teaching and research because it provides non-biased and clearly written updates on important developments.
