Episode 7 features an interview with Peter Whitehouse MD, PhD and Lon Schneider MD, MS exploring dementia and mild cognitive impairment. We chat about the medicalization of normal aging, the overdiagnosis of mild cognitive impairment, problems with new drugs and tests for Alzheimer’s disease, and how to prevent dementia. 

Pharmanipulation is produced by PharmedOut, a project at Georgetown University Medical Center that advances evidence-based prescribing.

Additional Resources

PharmedOut resources on Alzheimer’s and Mild Cognitive Impairment: https://sites.google.com/georgetown.edu/pharmedout/advocacy/alzheimers-and-mild-cognitive-impairment?authuser=0

Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. Link: https://www.thelancet.com/article/S0140-6736(20)30367-6/fulltext

Making the Case for Accelerated Withdrawal of Aducanumab. Link: https://content.iospress.com/articles/journal-of-alzheimers-disease/jad220262

Dr. Peter Whitehouse’s latest letter to the editor, “Cummings column on Alzheimer treatments skips over a few key things.” Link: https://www.cleveland.com/letters/2023/10/cummings-column-on-alzheimer-treatments-skips-over-a-few-key-things.html

American Dementia: Brain Health in an Unhealthy Society by Danny George PhD and Peter Whitehouse MD, PhD. Link: https://www.press.jhu.edu/books/title/12394/american-dementia

The Myth of Alzheimer’s: What You Aren't Being Told About Today's Most Dreaded Diagnosis by Peter Whitehouse MD, PhD and Danny George MSc. Link: https://us.macmillan.com/books/9780312368173/themythofalzheimers